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1
Drug release from hydroethanolic gels. Effect of drug's lipophilicity (log P), polymer–drug interactions and solvent lipophilicity
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Artigo
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Drug release from hydroethanolic gels. Effect of drug's lipophilicity (log P), polymer–drug interactions and solvent lipophilicity

Sawant, Prashant D. ; Luu, Dewitt ; Ye, Rose ; Buchta, Richard

International journal of pharmaceutics, 2010-08, Vol.396 (1), p.45-52 [Periódico revisado por pares]

Amsterdam: Elsevier B.V

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2
Calculation of drug lipophilicity the hydrophobic fragmental constant approach
Material Type:
Livro
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Calculation of drug lipophilicity the hydrophobic fragmental constant approach

Roelof F. Rekker Raimund Mannhold 1948-

Weinheim VCH New York c1992

Localização: CQ - Conjunto das Químicas    (615.19 R381c e.2 )(Acessar)

3
Edible solid lipid nanoparticles (SLN) as carrier system for antioxidants of different lipophilicity
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Artigo
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Edible solid lipid nanoparticles (SLN) as carrier system for antioxidants of different lipophilicity

Oehlke, Kathleen ; Behsnilian, Diana ; Mayer-Miebach, Esther ; Weidler, Peter G ; Greiner, Ralf Ceña, Valentin

PloS one, 2017-02, Vol.12 (2), p.e0171662-e0171662 [Periódico revisado por pares]

United States: Public Library of Science

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4
Calculation of molecular lipophilicity: State-of-the-art and comparison of log P methods on more than 96,000 compounds
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Artigo
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Calculation of molecular lipophilicity: State-of-the-art and comparison of log P methods on more than 96,000 compounds

Mannhold, Raimund ; Poda, Gennadiy I. ; Ostermann, Claude ; Tetko, Igor V.

Journal of pharmaceutical sciences, 2009-03, Vol.98 (3), p.861-893 [Periódico revisado por pares]

Hoboken: Wiley Subscription Services, Inc., A Wiley Company

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5
Lipophilicity and hydrophobicity considerations in bio‐enabling oral formulations approaches – a PEARRL review
Material Type:
Artigo
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Lipophilicity and hydrophobicity considerations in bio‐enabling oral formulations approaches – a PEARRL review

Ditzinger, Felix ; Price, Daniel J. ; Ilie, Alexandra‐Roxana ; Köhl, Niklas J. ; Jankovic, Sandra ; Tsakiridou, Georgia ; Aleandri, Simone ; Kalantzi, Lida ; Holm, René ; Nair, Anita ; Saal, Christoph ; Griffin, Brendan ; Kuentz, Martin

Journal of pharmacy and pharmacology, 2019-04, Vol.71 (4), p.464-482 [Periódico revisado por pares]

England: Wiley Subscription Services, Inc

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6
Hyperbranched polysiloxane-based probe with enhanced lipophilicity for visualizing ONOO− fluctuations in endoplasmic reticulum
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Artigo
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Hyperbranched polysiloxane-based probe with enhanced lipophilicity for visualizing ONOO− fluctuations in endoplasmic reticulum

Zhang, Kun ; Zhang, Yafang ; Lan, Ying ; Wang, Fanfan ; Gou, Zhiming ; Yan, Mei ; Zuo, Yujing

Analytica chimica acta, 2023-04, Vol.1249, p.340939-340939, Article 340939 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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7
Accurate Lipophilicity (log P) Measurements Inform on Subtle Stereoelectronic Effects in Fluorine Chemistry
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Artigo
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Accurate Lipophilicity (log P) Measurements Inform on Subtle Stereoelectronic Effects in Fluorine Chemistry

O'Hagan, David ; Young, Robert J.

Angewandte Chemie (International ed.), 2016-03, Vol.55 (12), p.3858-3860 [Periódico revisado por pares]

Germany: Blackwell Publishing Ltd

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8
Investigating the Influence of (Deoxy)fluorination on the Lipophilicity of Non-UV-Active Fluorinated Alkanols and Carbohydrates by a New log P Determination Method
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Artigo
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Investigating the Influence of (Deoxy)fluorination on the Lipophilicity of Non-UV-Active Fluorinated Alkanols and Carbohydrates by a New log P Determination Method

Linclau, Bruno ; Wang, Zhong ; Compain, Guillaume ; Paumelle, Vincent ; Fontenelle, Clement Q. ; Wells, Neil ; Weymouth-Wilson, Alex

Angewandte Chemie (International ed.), 2016-01, Vol.55 (2), p.674-678 [Periódico revisado por pares]

Weinheim: WILEY-VCH Verlag

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9
Drug‐Like Properties in Macrocycles above MW 1000: Backbone Rigidity versus Side‐Chain Lipophilicity
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Artigo
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Drug‐Like Properties in Macrocycles above MW 1000: Backbone Rigidity versus Side‐Chain Lipophilicity

Furukawa, Akihiro ; Schwochert, Joshua ; Pye, Cameron R. ; Asano, Daigo ; Edmondson, Quinn D. ; Turmon, Alexandra C. ; Klein, Victoria G. ; Ono, Satoshi ; Okada, Okimasa ; Lokey, R. Scott

Angewandte Chemie (International ed.), 2020-11, Vol.59 (48), p.21571-21577 [Periódico revisado por pares]

Germany: Wiley Subscription Services, Inc

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10
Systematic Investigation of Lipophilicity Modulation by Aliphatic Fluorination Motifs
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Artigo
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Systematic Investigation of Lipophilicity Modulation by Aliphatic Fluorination Motifs

Jeffries, Benjamin ; Wang, Zhong ; Felstead, Hannah R ; Le Questel, Jean-Yves ; Scott, James S ; Chiarparin, Elisabetta ; Graton, Jérôme ; Linclau, Bruno

Journal of medicinal chemistry, 2020-02, Vol.63 (3), p.1002-1031 [Periódico revisado por pares]

United States: American Chemical Society

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Deste Autor:

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  2. Amaral, A
  3. El Seoud, O
  4. Azevedo, E
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