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Genetics of coronary artery disease: discovery, biology and clinical translation
Genetics of coronary artery disease: discovery, biology and clinical translation
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Genetics of coronary artery disease: discovery, biology and clinical translation

Khera, Amit V ; Kathiresan, Sekar

Nature reviews. Genetics, 2017-06, Vol.18 (6), p.331-344 [Periódico revisado por pares]

England: Nature Publishing Group

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2
Association between adiposity and cardiovascular outcomes: an umbrella review and meta-analysis of observational and Mendelian randomization studies
Association between adiposity and cardiovascular outcomes: an umbrella review and meta-analysis of observational and Mendelian randomization studies
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Association between adiposity and cardiovascular outcomes: an umbrella review and meta-analysis of observational and Mendelian randomization studies

Kim, Min Seo ; Kim, Won Jun ; Khera, Amit V ; Kim, Jong Yeob ; Yon, Dong Keon ; Lee, Seung Won ; Shin, Jae Il ; Won, Hong-Hee

European heart journal, 2021-09, Vol.42 (34), p.3388-3403 [Periódico revisado por pares]

England: Oxford University Press

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3
Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood
Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood
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Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood

Khera, Amit V. ; Chaffin, Mark ; Wade, Kaitlin H. ; Zahid, Sohail ; Brancale, Joseph ; Xia, Rui ; Distefano, Marina ; Senol-Cosar, Ozlem ; Haas, Mary E. ; Bick, Alexander ; Aragam, Krishna G. ; Lander, Eric S. ; Smith, George Davey ; Mason-Suares, Heather ; Fornage, Myriam ; Lebo, Matthew ; Timpson, Nicholas J. ; Kaplan, Lee M. ; Kathiresan, Sekar

Cell, 2019-04, Vol.177 (3), p.587-596.e9 [Periódico revisado por pares]

United States: Elsevier Inc

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4
Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease
Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease
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Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease

Khera, Amit V ; Emdin, Connor A ; Drake, Isabel ; Natarajan, Pradeep ; Bick, Alexander G ; Cook, Nancy R ; Chasman, Daniel I ; Baber, Usman ; Mehran, Roxana ; Rader, Daniel J ; Fuster, Valentin ; Boerwinkle, Eric ; Melander, Olle ; Orho-Melander, Marju ; Ridker, Paul M ; Kathiresan, Sekar

The New England journal of medicine, 2016-12, Vol.375 (24), p.2349-2358 [Periódico revisado por pares]

United States: Massachusetts Medical Society

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5
Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions
Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions
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Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions

Fahed, Akl C ; Wang, Minxian ; Homburger, Julian R ; Patel, Aniruddh P ; Bick, Alexander G ; Neben, Cynthia L ; Lai, Carmen ; Brockman, Deanna ; Philippakis, Anthony ; Ellinor, Patrick T ; Cassa, Christopher A ; Lebo, Matthew ; Ng, Kenney ; Lander, Eric S ; Zhou, Alicia Y ; Kathiresan, Sekar ; Khera, Amit V

Nature communications, 2020-08, Vol.11 (1), p.3635-3635, Article 3635 [Periódico revisado por pares]

England: Nature Publishing Group

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6
Improving reporting standards for polygenic scores in risk prediction studies
Improving reporting standards for polygenic scores in risk prediction studies
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Improving reporting standards for polygenic scores in risk prediction studies

Wand, Hannah ; Lambert, Samuel A ; Tamburro, Cecelia ; Iacocca, Michael A ; O'Sullivan, Jack W ; Sillari, Catherine ; Kullo, Iftikhar J ; Rowley, Robb ; Dron, Jacqueline S ; Brockman, Deanna ; Venner, Eric ; McCarthy, Mark I ; Antoniou, Antonis C ; Easton, Douglas F ; Hegele, Robert A ; Khera, Amit V ; Chatterjee, Nilanjan ; Kooperberg, Charles ; Edwards, Karen ; Vlessis, Katherine ; Kinnear, Kim ; Danesh, John N ; Parkinson, Helen ; Ramos, Erin M ; Roberts, Megan C ; Ormond, Kelly E ; Khoury, Muin J ; Janssens, A Cecile J W ; Goddard, Katrina A B ; Kraft, Peter ; MacArthur, Jaqueline A L ; Inouye, Michael ; Wojcik, Genevieve L

Nature (London), 2021-03, Vol.591 (7849), p.211-219 [Periódico revisado por pares]

England: Nature Publishing Group

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7
Leveraging fine-mapping and multipopulation training data to improve cross-population polygenic risk scores
Leveraging fine-mapping and multipopulation training data to improve cross-population polygenic risk scores
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Leveraging fine-mapping and multipopulation training data to improve cross-population polygenic risk scores

Weissbrod, Omer ; Kanai, Masahiro ; Shi, Huwenbo ; Gazal, Steven ; Peyrot, Wouter J ; Khera, Amit V ; Okada, Yukinori ; Martin, Alicia R ; Finucane, Hilary K ; Price, Alkes L

Nature genetics, 2022-04, Vol.54 (4), p.450-458 [Periódico revisado por pares]

United States: Nature Publishing Group

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8
The potential of polygenic scores to improve cost and efficiency of clinical trials
The potential of polygenic scores to improve cost and efficiency of clinical trials
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The potential of polygenic scores to improve cost and efficiency of clinical trials

Fahed, Akl C ; Philippakis, Anthony A ; Khera, Amit V

Nature communications, 2022-05, Vol.13 (1), p.2922-2922, Article 2922 [Periódico revisado por pares]

England: Nature Publishing Group

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9
A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease
A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease
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A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease

Emdin, Connor A ; Haas, Mary E ; Khera, Amit V ; Aragam, Krishna ; Chaffin, Mark ; Klarin, Derek ; Hindy, George ; Jiang, Lan ; Wei, Wei-Qi ; Feng, Qiping ; Karjalainen, Juha ; Havulinna, Aki ; Kiiskinen, Tuomo ; Bick, Alexander ; Ardissino, Diego ; Wilson, James G ; Schunkert, Heribert ; McPherson, Ruth ; Watkins, Hugh ; Elosua, Roberto ; Bown, Matthew J ; Samani, Nilesh J ; Baber, Usman ; Erdmann, Jeanette ; Gupta, Namrata ; Danesh, John ; Saleheen, Danish ; Chang, Kyong-Mi ; Vujkovic, Marijana ; Voight, Ben ; Damrauer, Scott ; Lynch, Julie ; Kaplan, David ; Serper, Marina ; Tsao, Philip ; Mercader, Josep ; Hanis, Craig ; Daly, Mark ; Denny, Joshua ; Gabriel, Stacey ; Kathiresan, Sekar Murdock, Deborah G.

PLoS genetics, 2020-04, Vol.16 (4), p.e1008629 [Periódico revisado por pares]

United States: Public Library of Science

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10
Cholesterol Efflux Capacity, High-Density Lipoprotein Function, and Atherosclerosis
Cholesterol Efflux Capacity, High-Density Lipoprotein Function, and Atherosclerosis
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Cholesterol Efflux Capacity, High-Density Lipoprotein Function, and Atherosclerosis

Khera, Amit V ; Cuchel, Marina ; de la Llera-Moya, Margarita ; Rodrigues, Amrith ; Burke, Megan F ; Jafri, Kashif ; French, Benjamin C ; Phillips, Julie A ; Mucksavage, Megan L ; Wilensky, Robert L ; Mohler, Emile R ; Rothblat, George H ; Rader, Daniel J

The New England journal of medicine, 2011-01, Vol.364 (2), p.127-135 [Periódico revisado por pares]

Waltham, MA: Massachusetts Medical Society

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