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Efficacy and genomic analysis of HER2-mutant, metastatic triple-negative breast cancer treated with neratinib alone or in combination with trastuzumab in the phase 2 SUMMIT basket trialJhaveri, Komal L ; Hurvitz, Sara A ; Brufsky, Adam ; Bose, Ron ; de Miguel, Maria J ; Evron, Ella ; Unni, Nisha ; Reid, Sonya A ; Quinn, David I ; Mahalingam, Devalingam ; Saura, Cristina ; Garcia-Saenz, Jose A ; Martinez-Bueno, Alejandro ; Guerrero, Angel ; De La Fouchardiere, Christelle ; Wildiers, Hans ; Bischof, Georg Friedrich ; Bebchuk, Judith D ; Eli, Lisa DeFazio ; Solit, David BJOURNAL OF CLINICAL ONCOLOGY, 2024, Vol.42 (16)LIPPINCOTT WILLIAMS & WILKINSTexto completo disponível |
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Material Type: Outros
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StrateGIST 1: A first-in-human (FIH), phase 1 study of IDRX-42 in patients with metastatic gastrointestinal stromal tumors resistant to prior treatment with tyrosine kinase inhibitors (TKIs)Schoffski, Patrick ; Heinrich, Michael C ; Trent, Jonathan C ; Serrano, Cesar ; Bauer, Sebastian ; von Mehren, Margaret ; Somaiah, Neeta ; Reichardt, Peter ; Demetri, George D ; Lydon, Nick ; Verweij, Jaap ; Kadambi, Vivek ; Christo, Jessica ; Kim, Sean ; Johnson, Debbie ; Shao, James ; George, SuzanneJOURNAL OF CLINICAL ONCOLOGY, 2024, Vol.42 (16)LIPPINCOTT WILLIAMS & WILKINSTexto completo disponível |
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Material Type: Outros
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Circulating tumor DNA (ctDNA) analyses of the phase III VOYAGER trial: KIT mutational landscape and outcomes in patients with advanced gastrointestinal stromal tumor (GIST)Serrano, Cesar ; Bauer, Sebastian ; Gomez-Peregrina, David ; Kang, Yoon-Koo ; Jones, Robin L ; Rutkowski, Piotr ; Mir, Olivier ; Heinrich, Michael C ; Tap, William D ; Newberry, Kate ; Grassian, Alexandra ; Miller, Stephen G ; Shi, Hongliang ; Schoffski, Patrick ; Pantaleo, Maria A ; Von Mehren, Margaret ; Trent, Jonathan C ; George, SuzanneJOURNAL OF CLINICAL ONCOLOGY, 2022, Vol.40 (16)LIPPINCOTT WILLIAMS & WILKINSTexto completo disponível |