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The molecular basis of JAK/STAT inhibition by SOCS1
The molecular basis of JAK/STAT inhibition by SOCS1
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The molecular basis of JAK/STAT inhibition by SOCS1

Liau, Nicholas P D ; Laktyushin, Artem ; Lucet, Isabelle S ; Murphy, James M ; Yao, Shenggen ; Whitlock, Eden ; Callaghan, Kimberley ; Nicola, Nicos A ; Kershaw, Nadia J ; Babon, Jeffrey J

Nature communications, 2018-04, Vol.9 (1), p.1558-14, Article 1558 [Periódico revisado por pares]

England: Nature Publishing Group

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2
Heterodimeric JAK―STAT activation as a mechanism of persistence to JAK2 inhibitor therapy
Heterodimeric JAK―STAT activation as a mechanism of persistence to JAK2 inhibitor therapy
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Heterodimeric JAK―STAT activation as a mechanism of persistence to JAK2 inhibitor therapy

KOPPIKAR, Priya ; BHAGWAT, Neha ; LEUNG, Laura ; WEINSTEIN, Abby ; MARUBAYASHI, Sachie ; GOEL, Aviva ; GÖNEN, Mithat ; ESTROV, Zeev ; EBERT, Benjamin L ; CHIOSIS, Gabriela ; NIMER, Stephen D ; BERNSTEIN, Bradley E ; KILPIVAARA, Outi ; VERSTOVSEK, Srdan ; LEVINE, Ross L ; MANSHOURI, Taghi ; ADLI, Mazhar ; HRICIK, Todd ; FAN LIU ; SAUNDERS, Lindsay M ; MULLALLY, Ann ; ABDEL-WAHAB, Omar

Nature (London), 2012-09, Vol.489 (7414), p.155-159 [Periódico revisado por pares]

London: Nature Publishing Group

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3
Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy
Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy
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Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy

Porpaczy, Edit ; Tripolt, Sabrina ; Hoelbl-Kovacic, Andrea ; Gisslinger, Bettina ; Bago-Horvath, Zsuzsanna ; Casanova-Hevia, Emilio ; Clappier, Emmanuelle ; Decker, Thomas ; Fajmann, Sabine ; Fux, Daniela A. ; Greiner, Georg ; Gueltekin, Sinan ; Heller, Gerwin ; Herkner, Harald ; Hoermann, Gregor ; Kiladjian, Jean-Jacques ; Kolbe, Thomas ; Kornauth, Christoph ; Krauth, Maria-Theresa ; Kralovics, Robert ; Muellauer, Leonhard ; Mueller, Mathias ; Prchal-Murphy, Michaela ; Putz, Eva Maria ; Raffoux, Emmanuel ; Schiefer, Ana-Iris ; Schmetterer, Klaus ; Schneckenleithner, Christine ; Simonitsch-Klupp, Ingrid ; Skrabs, Cathrin ; Sperr, Wolfgang R. ; Staber, Philipp Bernhard ; Strobl, Birgit ; Valent, Peter ; Jaeger, Ulrich ; Gisslinger, Heinz ; Sexl, Veronika

Blood, 2018-08, Vol.132 (7), p.694-706 [Periódico revisado por pares]

United States: Elsevier Inc

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4
JAK inhibition in the treatment of diabetic kidney disease
JAK inhibition in the treatment of diabetic kidney disease
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JAK inhibition in the treatment of diabetic kidney disease

Brosius, Frank C. ; Tuttle, Katherine R. ; Kretzler, Matthias

Diabetologia, 2016-08, Vol.59 (8), p.1624-1627 [Periódico revisado por pares]

Berlin/Heidelberg: Springer Berlin Heidelberg

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5
Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages
Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages
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Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages

Runtsch, Marah C. ; Angiari, Stefano ; Hooftman, Alexander ; Wadhwa, Ridhima ; Zhang, Yanling ; Zheng, Yunan ; Spina, Joseph S. ; Ruzek, Melanie C. ; Argiriadi, Maria A. ; McGettrick, Anne F. ; Mendez, Rui Santalla ; Zotta, Alessia ; Peace, Christian G. ; Walsh, Aoife ; Chirillo, Roberta ; Hams, Emily ; Fallon, Padraic G. ; Jayaraman, Ranjith ; Dua, Kamal ; Brown, Alexandra C. ; Kim, Richard Y. ; Horvat, Jay C. ; Hansbro, Philip M. ; Wang, Chu ; O’Neill, Luke A.J.

Cell metabolism, 2022-03, Vol.34 (3), p.487-501.e8 [Periódico revisado por pares]

United States: Elsevier Inc

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6
Baricitinib, a drug with potential effect to prevent SARS-COV-2 from entering target cells and control cytokine storm induced by COVID-19
Baricitinib, a drug with potential effect to prevent SARS-COV-2 from entering target cells and control cytokine storm induced by COVID-19
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Baricitinib, a drug with potential effect to prevent SARS-COV-2 from entering target cells and control cytokine storm induced by COVID-19

Zhang, Xiuhong ; Zhang, Yan ; Qiao, Weizhen ; Zhang, Ji ; Qi, Zhigang

International immunopharmacology, 2020-09, Vol.86, p.106749-106749, Article 106749 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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7
Structure of the pseudokinase–kinase domains from protein kinase TYK2 reveals a mechanism for Janus kinase (JAK) autoinhibition
Structure of the pseudokinase–kinase domains from protein kinase TYK2 reveals a mechanism for Janus kinase (JAK) autoinhibition
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Structure of the pseudokinase–kinase domains from protein kinase TYK2 reveals a mechanism for Janus kinase (JAK) autoinhibition

Lupardus, Patrick J. ; Ultsch, Mark ; Wallweber, Heidi ; Kohli, Pawan Bir ; Johnson, Adam R. ; Eigenbrot, Charles

Proceedings of the National Academy of Sciences - PNAS, 2014-06, Vol.111 (22), p.8025-8030 [Periódico revisado por pares]

United States: National Academy of Sciences

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8
The molecular regulation of Janus kinase (JAK) activation
The molecular regulation of Janus kinase (JAK) activation
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The molecular regulation of Janus kinase (JAK) activation

Babon, Jeffrey J ; Lucet, Isabelle S ; Murphy, James M ; Nicola, Nicos A ; Varghese, Leila N

Biochemical journal, 2014-08, Vol.462 (1), p.1-13 [Periódico revisado por pares]

England

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9
A Jak1/2 inhibitor, baricitinib, inhibits osteoclastogenesis by suppressing RANKL expression in osteoblasts in vitro
A Jak1/2 inhibitor, baricitinib, inhibits osteoclastogenesis by suppressing RANKL expression in osteoblasts in vitro
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A Jak1/2 inhibitor, baricitinib, inhibits osteoclastogenesis by suppressing RANKL expression in osteoblasts in vitro

Murakami, Kohei ; Kobayashi, Yasuhiro ; Uehara, Shunsuke ; Suzuki, Takako ; Koide, Masanori ; Yamashita, Teruhito ; Nakamura, Midori ; Takahashi, Naoyuki ; Kato, Hiroyuki ; Udagawa, Nobuyuki ; Nakamura, Yukio Reddy, Sakamuri V.

PloS one, 2017-07, Vol.12 (7), p.e0181126-e0181126 [Periódico revisado por pares]

United States: Public Library of Science

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10
Molecular Pathways: JAK/STAT Pathway: Mutations, Inhibitors, and Resistance
Molecular Pathways: JAK/STAT Pathway: Mutations, Inhibitors, and Resistance
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Molecular Pathways: JAK/STAT Pathway: Mutations, Inhibitors, and Resistance

QUINTAS-CARDAMA, Alfonso ; VERSTOVSEK, Srdan

Clinical cancer research, 2013-04, Vol.19 (8), p.1933-1940 [Periódico revisado por pares]

Philadelphia, PA: American Association for Cancer Research

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