Result Number | Material Type | Add to My Shelf Action | Record Details and Options |
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1 |
Material Type: Artigo
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Structural optimization and additional targets identification of antisense oligonucleotide G3139 encapsulated in a neutral cytidinyl-lipid combined with a cationic lipid in vitro and in vivoMa, Yuan ; Zhao, Wenting ; Li, Yiding ; Pan, Yufei ; Wang, Shuhe ; Zhu, Yuejie ; Kong, Lingxuan ; Guan, Zhu ; Wang, Jiancheng ; Zhang, Lihe ; Yang, ZhenjunBiomaterials, 2019-03, Vol.197, p.182-193 [Periódico revisado por pares]Netherlands: Elsevier LtdTexto completo disponível |
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2 |
Material Type: Artigo
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Integrated Safety Assessment of 2′-O-Methoxyethyl Chimeric Antisense Oligonucleotides in NonHuman Primates and Healthy Human VolunteersCrooke, Stanley T ; Baker, Brenda F ; Kwoh, T Jesse ; Cheng, Wei ; Schulz, Dan J ; Xia, Shuting ; Salgado, Nelson ; Bui, Huynh-Hoa ; Hart, Christopher E ; Burel, Sebastien A ; Younis, Husam S ; Geary, Richard S ; Henry, Scott P ; Bhanot, SanjayMolecular therapy, 2016-10, Vol.24 (10), p.1771-1782 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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3 |
Material Type: Artigo
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The Effects of 2′-O-Methoxyethyl Containing Antisense Oligonucleotides on Platelets in Human Clinical TrialsCrooke, Stanley T. ; Baker, Brenda F. ; Witztum, Joseph L. ; Kwoh, T. Jesse ; Pham, Nguyen C. ; Salgado, Nelson ; McEvoy, Bradley W. ; Cheng, Wei ; Hughes, Steven G. ; Bhanot, Sanjay ; Geary, Richard S.Nucleic acid therapeutics, 2017-06, Vol.27 (3), p.121-129 [Periódico revisado por pares]United States: Mary Ann Liebert, IncTexto completo disponível |
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4 |
Material Type: Artigo
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Two disparate ligand-binding sites in the human P2Y1 receptorZhang, Dandan ; Gao, Zhan-Guo ; Zhang, Kaihua ; Kiselev, Evgeny ; Crane, Steven ; Wang, Jiang ; Paoletta, Silvia ; Yi, Cuiying ; Ma, Limin ; Zhang, Wenru ; Han, Gye Won ; Liu, Hong ; Cherezov, Vadim ; Katritch, Vsevolod ; Jiang, Hualiang ; Stevens, Raymond C ; Jacobson, Kenneth A ; Zhao, Qiang ; Wu, BeiliNature (London), 2015-03, Vol.520 (7547), p.317-321 [Periódico revisado por pares]EnglandTexto completo disponível |
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5 |
Material Type: Artigo
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Agonist-bound structure of the human P2Y12 receptorZhang, Jin ; Zhang, Kaihua ; Gao, Zhan-Guo ; Paoletta, Silvia ; Zhang, Dandan ; Han, Gye Won ; Li, Tingting ; Ma, Limin ; Zhang, Wenru ; Müller, Christa E ; Yang, Huaiyu ; Jiang, Hualiang ; Cherezov, Vadim ; Katritch, Vsevolod ; Jacobson, Kenneth A ; Stevens, Raymond C ; Wu, Beili ; Zhao, QiangNature (London), 2014-05, Vol.509 (7498), p.119-122 [Periódico revisado por pares]EnglandTexto completo disponível |
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6 |
Material Type: Artigo
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Concentrations of 6-Thioguanine Nucleotide Correlate With Trough Levels of Infliximab in Patients With Inflammatory Bowel Disease on Combination TherapyYarur, Andres J ; Kubiliun, Maddie J ; Czul, Frank ; Sussman, Daniel A ; Quintero, Maria A ; Jain, Anjali ; Drake, Katherine A ; Hauenstein, Scott I ; Lockton, Steven ; Deshpande, Amar R ; Barkin, Jamie S ; Singh, Sharat ; Abreu, Maria TClinical gastroenterology and hepatology, 2015-06, Vol.13 (6), p.1118-1124.e3 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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7 |
Material Type: Artigo
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Oxidatively-generated damage to DNA and proteins mediated by photosensitized UVABrem, Reto ; Guven, Melisa ; Karran, PeterFree radical biology & medicine, 2017-06, Vol.107, p.101-109 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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8 |
Material Type: Artigo
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Antisense oligonucleotides: the next frontier for treatment of neurological disordersRinaldi, Carlo ; Wood, Matthew J ANature reviews. Neurology, 2018-01, Vol.14 (1), p.9-21 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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9 |
Material Type: Artigo
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Synthesis of 4′‐Thiomodified c‐di‐AMP AnalogsSaito‐Tarashima, Noriko ; Kagotani, Yuma ; Inoue, Syuya ; Kinoshita, Mao ; Minakawa, NoriakiCurrent protocols, 2023-09, Vol.3 (9), p.e892-e892Texto completo disponível |
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10 |
Material Type: Artigo
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Lipid-modified oligonucleotide conjugates: Insights into gene silencing, interaction with model membranes and cellular uptake mechanismsUgarte-Uribe, Begoña ; Grijalvo, Santiago ; Pertíñez, Samuel Núñez ; Busto, Jon V. ; Martín, César ; Alagia, Adele ; Goñi, Félix M. ; Eritja, Ramón ; Alkorta, ItziarBioorganic & medicinal chemistry, 2017-01, Vol.25 (1), p.175-186 [Periódico revisado por pares]England: Elsevier LtdTexto completo disponível |