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1
Glutathione transferases
Glutathione transferases
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Artigo 		Adicionar ao Meu Espaço

Glutathione transferases

HAYES, John D ; FLANAGAN, Jack U ; JOWSEY, Ian R

Annual review of pharmacology and toxicology, 2005-01, Vol.45 (1), p.51-88 [Periódico revisado por pares]

Palo Alto, CA: Annual Reviews

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2
Binding mode of the breakthrough inhibitor AZD9291 to epidermal growth factor receptor revealed
Binding mode of the breakthrough inhibitor AZD9291 to epidermal growth factor receptor revealed
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Binding mode of the breakthrough inhibitor AZD9291 to epidermal growth factor receptor revealed

Yosaatmadja, Yuliana ; Silva, Shevan ; Dickson, James M. ; Patterson, Adam V. ; Smaill, Jeff B. ; Flanagan, Jack U. ; McKeage, Mark J. ; Squire, Christopher J.

Journal of structural biology, 2015-12, Vol.192 (3), p.539-544 [Periódico revisado por pares]

United States: Elsevier Inc

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3
Targeting GLUT1 and the Warburg effect in renal cell carcinoma by chemical synthetic lethality
Targeting GLUT1 and the Warburg effect in renal cell carcinoma by chemical synthetic lethality
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Targeting GLUT1 and the Warburg effect in renal cell carcinoma by chemical synthetic lethality

Chan, Denise A ; Sutphin, Patrick D ; Nguyen, Phuong ; Turcotte, Sandra ; Lai, Edwin W ; Banh, Alice ; Reynolds, Gloria E ; Chi, Jen-Tsan ; Wu, Jason ; Solow-Cordero, David E ; Bonnet, Muriel ; Flanagan, Jack U ; Bouley, Donna M ; Graves, Edward E ; Denny, William A ; Hay, Michael P ; Giaccia, Amato J

Science translational medicine, 2011-08, Vol.3 (94), p.94ra70-94ra70 [Periódico revisado por pares]

United States: The American Association for the Advancement of Science

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4
Diverse mechanisms activate the PI 3-kinase/mTOR pathway in melanomas: implications for the use of PI 3-kinase inhibitors to overcome resistance to inhibitors of BRAF and MEK
Diverse mechanisms activate the PI 3-kinase/mTOR pathway in melanomas: implications for the use of PI 3-kinase inhibitors to overcome resistance to inhibitors of BRAF and MEK
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Diverse mechanisms activate the PI 3-kinase/mTOR pathway in melanomas: implications for the use of PI 3-kinase inhibitors to overcome resistance to inhibitors of BRAF and MEK

Tran, Khanh B ; Kolekar, Sharada ; Jabed, Anower ; Jaynes, Patrick ; Shih, Jen-Hsing ; Wang, Qian ; Flanagan, Jack U ; Rewcastle, Gordon W ; Baguley, Bruce C ; Shepherd, Peter R

BMC cancer, 2021-02, Vol.21 (1), p.136-136, Article 136 [Periódico revisado por pares]

England: BioMed Central Ltd

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5
Inhibitors of Discoidin Domain Receptor (DDR) Kinases for Cancer and Inflammation
Inhibitors of Discoidin Domain Receptor (DDR) Kinases for Cancer and Inflammation
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Inhibitors of Discoidin Domain Receptor (DDR) Kinases for Cancer and Inflammation

Denny, William A ; Flanagan, Jack U

Biomolecules (Basel, Switzerland), 2021-11, Vol.11 (11), p.1671 [Periódico revisado por pares]

Switzerland: MDPI AG

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6
A drug targeting only p110α can block phosphoinositide 3-kinase signalling and tumour growth in certain cell types
A drug targeting only p110α can block phosphoinositide 3-kinase signalling and tumour growth in certain cell types
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A drug targeting only p110α can block phosphoinositide 3-kinase signalling and tumour growth in certain cell types

Jamieson, Stephen ; Flanagan, Jack U ; Kolekar, Sharada ; Buchanan, Christina ; Kendall, Jackie D ; Lee, Woo-Jeong ; Rewcastle, Gordon W ; Denny, William A ; Singh, Ripudaman ; Dickson, James ; Baguley, Bruce C ; Shepherd, Peter R

Biochemical journal, 2011-08, Vol.438 (1), p.53-62 [Periódico revisado por pares]

England: Portland Press Ltd

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7
Discovery and evaluation of inhibitors to the immunosuppressive enzyme indoleamine 2,3-dioxygenase 1 (IDO1): Probing the active site-inhibitor interactions
Discovery and evaluation of inhibitors to the immunosuppressive enzyme indoleamine 2,3-dioxygenase 1 (IDO1): Probing the active site-inhibitor interactions
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Discovery and evaluation of inhibitors to the immunosuppressive enzyme indoleamine 2,3-dioxygenase 1 (IDO1): Probing the active site-inhibitor interactions

Tomek, Petr ; Palmer, Brian D. ; Flanagan, Jack U. ; Sun, Chuanwen ; Raven, Emma L. ; Ching, Lai-Ming

European journal of medicinal chemistry, 2017-01, Vol.126, p.983-996 [Periódico revisado por pares]

France: Elsevier Masson SAS

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8
Influence of Aldo-keto Reductase 1C3 in Prostate Cancer - A Mini Review
Influence of Aldo-keto Reductase 1C3 in Prostate Cancer - A Mini Review
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Influence of Aldo-keto Reductase 1C3 in Prostate Cancer - A Mini Review

Karunasinghe, Nishi ; Masters, Jonathan ; Flanagan, Jack U. ; Ferguson, Lynnette R.

Current cancer drug targets, 2017-01, Vol.17 (7), p.603-616 [Periódico revisado por pares]

Sharjah: Bentham Science Publishers Ltd

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9
Structure, function and inhibition of the phosphoinositide 3-kinase p110α enzyme
Structure, function and inhibition of the phosphoinositide 3-kinase p110α enzyme
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Structure, function and inhibition of the phosphoinositide 3-kinase p110α enzyme

Flanagan, Jack U ; Shepherd, Peter R

Biochemical Society transactions, 2014-02, Vol.42 (1), p.120-124 [Periódico revisado por pares]

England

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10
Evaluation of Novel Inhibitors of Tryptophan Dioxygenases for Enzyme and Species Selectivity Using Engineered Tumour Cell Lines Expressing Either Murine or Human IDO1 or TDO2
Evaluation of Novel Inhibitors of Tryptophan Dioxygenases for Enzyme and Species Selectivity Using Engineered Tumour Cell Lines Expressing Either Murine or Human IDO1 or TDO2
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Evaluation of Novel Inhibitors of Tryptophan Dioxygenases for Enzyme and Species Selectivity Using Engineered Tumour Cell Lines Expressing Either Murine or Human IDO1 or TDO2

Tijono, Sofian M ; Palmer, Brian D ; Tomek, Petr ; Flanagan, Jack U ; Henare, Kimiora ; Gamage, Swarna ; Braun, Lukas ; Ching, Lai-Ming

Pharmaceuticals (Basel, Switzerland), 2022-08, Vol.15 (9), p.1090 [Periódico revisado por pares]

Basel: MDPI AG

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