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Time Evolution of the Millisecond Allosteric Activation of Imidazole Glycerol Phosphate Synthase
Time Evolution of the Millisecond Allosteric Activation of Imidazole Glycerol Phosphate Synthase
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Time Evolution of the Millisecond Allosteric Activation of Imidazole Glycerol Phosphate Synthase

Calvó-Tusell, Carla ; Maria-Solano, Miguel A ; Osuna, Sílvia ; Feixas, Ferran

Journal of the American Chemical Society, 2022-04, Vol.144 (16), p.7146-7159 [Periódico revisado por pares]

United States: American Chemical Society

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2
Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis
Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis
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Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis

Zhou, Changyang ; Sun, Yidi ; Yan, Rui ; Liu, Yajing ; Zuo, Erwei ; Gu, Chan ; Han, Linxiao ; Wei, Yu ; Hu, Xinde ; Zeng, Rong ; Li, Yixue ; Zhou, Haibo ; Guo, Fan ; Yang, Hui

Nature (London), 2019-07, Vol.571 (7764), p.275-278 [Periódico revisado por pares]

England: Nature Publishing Group

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3
Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer
Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer
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Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer

Nilsson, Roland ; Jain, Mohit ; Madhusudhan, Nikhil ; Sheppard, Nina Gustafsson ; Strittmatter, Laura ; Kampf, Caroline ; Huang, Jenny ; Asplund, Anna ; Mootha, Vamsi K

Nature communications, 2014-01, Vol.5 (1), p.3128-3128, Article 3128 [Periódico revisado por pares]

England: Nature Publishing Group

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4
Evolution of new enzymes by gene duplication and divergence
Evolution of new enzymes by gene duplication and divergence
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Evolution of new enzymes by gene duplication and divergence

Copley, Shelley D.

The FEBS journal, 2020-04, Vol.287 (7), p.1262-1283 [Periódico revisado por pares]

England: Blackwell Publishing Ltd

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5
Modulation of Redox Homeostasis by Inhibition of MTHFD2 in Colorectal Cancer: Mechanisms and Therapeutic Implications
Modulation of Redox Homeostasis by Inhibition of MTHFD2 in Colorectal Cancer: Mechanisms and Therapeutic Implications
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Modulation of Redox Homeostasis by Inhibition of MTHFD2 in Colorectal Cancer: Mechanisms and Therapeutic Implications

Ju, Huai-Qiang ; Lu, Yun-Xin ; Chen, Dong-Liang ; Zuo, Zhi-Xiang ; Liu, Ze-Xian ; Wu, Qi-Nian ; Mo, Hai-Yu ; Wang, Zi-Xian ; Wang, De-Shen ; Pu, Heng-Ying ; Zeng, Zhao-Lei ; Li, Bo ; Xie, Dan ; Huang, Peng ; Hung, Mien-Chie ; Chiao, Paul J ; Xu, Rui-Hua

JNCI : Journal of the National Cancer Institute, 2019-06, Vol.111 (6), p.584-596 [Periódico revisado por pares]

United States: Oxford University Press

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6
hnRNPC regulates cancer-specific alternative cleavage and polyadenylation profiles
hnRNPC regulates cancer-specific alternative cleavage and polyadenylation profiles
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hnRNPC regulates cancer-specific alternative cleavage and polyadenylation profiles

Fischl, Harry ; Neve, Jonathan ; Wang, Zhiqiao ; Patel, Radhika ; Louey, Alastair ; Tian, Bin ; Furger, Andre

Nucleic acids research, 2019-08, Vol.47 (14), p.7580-7591 [Periódico revisado por pares]

England: Oxford University Press

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7
The folate cycle enzyme MTHFD2 induces cancer immune evasion through PD-L1 up-regulation
The folate cycle enzyme MTHFD2 induces cancer immune evasion through PD-L1 up-regulation
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The folate cycle enzyme MTHFD2 induces cancer immune evasion through PD-L1 up-regulation

Shang, Man ; Yang, Huijie ; Yang, Ran ; Chen, Tao ; Fu, Yuan ; Li, Yeyi ; Fang, Xianlong ; Zhang, Kangjian ; Zhang, Jianju ; Li, Hui ; Cao, Xueping ; Gu, Jinfa ; Xiao, Jianwen ; Zhang, Qi ; Liu, Xinyuan ; Yu, Qiujing ; Wang, Ting

Nature communications, 2021-03, Vol.12 (1), p.1940-16, Article 1940 [Periódico revisado por pares]

England: Nature Publishing Group

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8
Maximizing the potential of nitrilase: Unveiling their diversity, catalytic proficiency, and versatile applications
Maximizing the potential of nitrilase: Unveiling their diversity, catalytic proficiency, and versatile applications
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Maximizing the potential of nitrilase: Unveiling their diversity, catalytic proficiency, and versatile applications

Zhou, Shi-Peng ; Xue, Ya-Ping ; Zheng, Yu-Guo

Biotechnology advances, 2024-05, Vol.72, p.108352-108352, Article 108352 [Periódico revisado por pares]

England: Elsevier Inc

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9
Folate cycle enzyme MTHFD1L confers metabolic advantages in hepatocellular carcinoma
Folate cycle enzyme MTHFD1L confers metabolic advantages in hepatocellular carcinoma
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Folate cycle enzyme MTHFD1L confers metabolic advantages in hepatocellular carcinoma

Lee, Derek ; Xu, Iris Ming-Jing ; Chiu, David Kung-Chun ; Lai, Robin Kit-Ho ; Tse, Aki Pui-Wah ; Lan Li, Lynna ; Law, Cheuk-Ting ; Tsang, Felice Ho-Ching ; Wei, Larry Lai ; Chan, Cerise Yuen-Ki ; Wong, Chun-Ming ; Ng, Irene Oi-Lin ; Wong, Carmen Chak-Lui

The Journal of clinical investigation, 2017-05, Vol.127 (5), p.1856-1872 [Periódico revisado por pares]

United States: American Society for Clinical Investigation

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10
The Important Role of Halogen Bond in Substrate Selectivity of Enzymatic Catalysis
The Important Role of Halogen Bond in Substrate Selectivity of Enzymatic Catalysis
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The Important Role of Halogen Bond in Substrate Selectivity of Enzymatic Catalysis

Jiang, Shuiqin ; Zhang, Lujia ; Cui, Dongbin ; Yao, Zhiqiang ; Gao, Bei ; Lin, Jinping ; Wei, Dongzhi

Scientific reports, 2016-10, Vol.6 (1), p.34750-34750, Article 34750 [Periódico revisado por pares]

England: Nature Publishing Group

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