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The Effect of a Novel Highly Selective Inhibitor of the Sodium/Calcium Exchanger (NCX) on Cardiac Arrhythmias in In Vitro and In Vivo Experiments
The Effect of a Novel Highly Selective Inhibitor of the Sodium/Calcium Exchanger (NCX) on Cardiac Arrhythmias in In Vitro and In Vivo Experiments
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The Effect of a Novel Highly Selective Inhibitor of the Sodium/Calcium Exchanger (NCX) on Cardiac Arrhythmias in In Vitro and In Vivo Experiments

Kohajda, Zsófia ; Farkas-Morvay, Nikolett ; Jost, Norbert ; Nagy, Norbert ; Geramipour, Amir ; Horváth, András ; Varga, Richárd S ; Hornyik, Tibor ; Corici, Claudia ; Acsai, Károly ; Horváth, Balázs ; Prorok, János ; Ördög, Balázs ; Déri, Szilvia ; Tóth, Dániel ; Levijoki, Jouko ; Pollesello, Piero ; Koskelainen, Tuula ; Otsomaa, Leena ; Tóth, András ; Baczkó, István ; Leprán, István ; Nánási, Péter P ; Papp, Julius Gy ; Varró, András ; Virág, László Hund, Thomas

PloS one, 2016-11, Vol.11 (11), p.e0166041-e0166041 [Periódico revisado por pares]

United States: Public Library of Science

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2
Long‐term effects of Na+/Ca2+ exchanger inhibition with ORM‐11035 improves cardiac function and remodelling without lowering blood pressure in a model of heart failure with preserved ejection fraction
Long‐term effects of Na+/Ca2+ exchanger inhibition with ORM‐11035 improves cardiac function and remodelling without lowering blood pressure in a model of heart failure with preserved ejection fraction
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Long‐term effects of Na+/Ca2+ exchanger inhibition with ORM‐11035 improves cardiac function and remodelling without lowering blood pressure in a model of heart failure with preserved ejection fraction

Primessnig, Uwe ; Bracic, Taja ; Levijoki, Jouko ; Otsomaa, Leena ; Pollesello, Piero ; Falcke, Martin ; Pieske, Burkert ; Heinzel, Frank R.

European journal of heart failure, 2019-12, Vol.21 (12), p.1543-1552 [Periódico revisado por pares]

Oxford, UK: John Wiley & Sons, Ltd

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3
Long-term effects of Na + /Ca 2+ exchanger inhibition with ORM-11035 improves cardiac function and remodelling without lowering blood pressure in a model of heart failure with preserved ejection fraction
Long-term effects of Na + /Ca 2+ exchanger inhibition with ORM-11035 improves cardiac function and remodelling without lowering blood pressure in a model of heart failure with preserved ejection fraction
Material Type:
Artigo 		Adicionar ao Meu Espaço

Long-term effects of Na + /Ca 2+ exchanger inhibition with ORM-11035 improves cardiac function and remodelling without lowering blood pressure in a model of heart failure with preserved ejection fraction

Primessnig, Uwe ; Bracic, Taja ; Levijoki, Jouko ; Otsomaa, Leena ; Pollesello, Piero ; Falcke, Martin ; Pieske, Burkert ; Heinzel, Frank R

European journal of heart failure, 2019-12, Vol.21 (12), p.1543-1552 [Periódico revisado por pares]

England

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4
Discovery and characterization of ORM‐11372, a novel inhibitor of the sodium‐calcium exchanger with positive inotropic activity
Discovery and characterization of ORM‐11372, a novel inhibitor of the sodium‐calcium exchanger with positive inotropic activity
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Discovery and characterization of ORM‐11372, a novel inhibitor of the sodium‐calcium exchanger with positive inotropic activity

Otsomaa, Leena ; Levijoki, Jouko ; Wohlfahrt, Gerd ; Chapman, Hugh ; Koivisto, Ari‐Pekka ; Syrjänen, Kaisa ; Koskelainen, Tuula ; Peltokorpi, Saara‐Elisa ; Finckenberg, Piet ; Heikkilä, Aira ; Abi‐Gerges, Najah ; Ghetti, Andre ; Miller, Paul E. ; Page, Guy ; Mervaala, Eero ; Nagy, Norbert ; Kohajda, Zsófia ; Jost, Norbert ; Virág, László ; Varró, András ; Papp, Julius Gy

British journal of pharmacology, 2020-12, Vol.177 (24), p.5534-5554 [Periódico revisado por pares]

England: Blackwell Publishing Ltd

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5
European Medicinal Chemistry Leaders in Industry (EMCL) – On the Status and Future of Medicinal Chemistry Research in Europe
European Medicinal Chemistry Leaders in Industry (EMCL) – On the Status and Future of Medicinal Chemistry Research in Europe
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European Medicinal Chemistry Leaders in Industry (EMCL) – On the Status and Future of Medicinal Chemistry Research in Europe

Ali, Amjad ; Bauser, Marcus ; Bertrand, Sophie ; Blackaby, Wesley ; Boss, Christoph ; Bossart, Martin ; Hall, Adrian ; Binch, Hayley ; Czechtizky, Werngard ; Gijsen, Harrie ; Haning, Helmut ; Hartung, Ingo V. ; Kilburn, Paul ; Lassalle, Gilbert ; Lücking, Ulrich ; Mack, Jürgen ; Missbach, Martin ; Otsomaa, Leena ; Torrens, Antoni ; Wagner, Michael ; Walter, Magnus ; Weinstabl, Harald ; Hijfte, Luc ; Nussbaum, Franz

ChemMedChem, 2023-07, Vol.18 (13), p.e202300127-n/a [Periódico revisado por pares]

Germany: Wiley Subscription Services, Inc

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6
Inotropic effect of NCX inhibition depends on the relative activity of the reverse NCX assessed by a novel inhibitor ORM-10962 on canine ventricular myocytes
Inotropic effect of NCX inhibition depends on the relative activity of the reverse NCX assessed by a novel inhibitor ORM-10962 on canine ventricular myocytes
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Inotropic effect of NCX inhibition depends on the relative activity of the reverse NCX assessed by a novel inhibitor ORM-10962 on canine ventricular myocytes

Oravecz, Kinga ; Kormos, Anita ; Gruber, Andrea ; Márton, Zoltán ; Kohajda, Zsófia ; Mirzaei, Leila ; Jost, Norbert ; Levijoki, Jouko ; Pollesello, Piero ; Koskelainen, Tuula ; Otsomaa, Leena ; Tóth, András ; Papp, Julius Gy ; Nánási, Péter P. ; Antoons, Gudrun ; Varró, András ; Acsai, Károly ; Nagy, Norbert

European journal of pharmacology, 2018-01, Vol.818, p.278-286 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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7
A new access to enantiomerically pure deoxy aminohexoses: Methyl 4-amino-4,6-dideoxygulopyranoside and epi-tolyposamine
A new access to enantiomerically pure deoxy aminohexoses: Methyl 4-amino-4,6-dideoxygulopyranoside and epi-tolyposamine
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A new access to enantiomerically pure deoxy aminohexoses: Methyl 4-amino-4,6-dideoxygulopyranoside and epi-tolyposamine

Koskinen, Ari M.P. ; Otsomaa, Leena A.

Tetrahedron, , Vol.53 (18), p.6473-6484 [Periódico revisado por pares]

Elsevier Ltd

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8
Long‐term effects of Na+/Ca2+ exchanger inhibition with ORM‐11035 improves cardiac function and remodelling without lowering blood pressure in a model of heart failure with preserved ejection fraction
Long‐term effects of Na+/Ca2+ exchanger inhibition with ORM‐11035 improves cardiac function and remodelling without lowering blood pressure in a model of heart failure with preserved ejection fraction
Material Type:
Artigo 		Adicionar ao Meu Espaço

Long‐term effects of Na+/Ca2+ exchanger inhibition with ORM‐11035 improves cardiac function and remodelling without lowering blood pressure in a model of heart failure with preserved ejection fraction

Primessnig, Uwe ; Bracic, Taja ; Levijoki, Jouko ; Otsomaa, Leena ; Pollesello, Piero ; Falcke, Martin ; Pieske, Burkert ; Heinzel, Frank R

2019

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