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Refinado por: Base de dados/Biblioteca: BACON - Mir@bel - GLOBAL_LIBRESACCES remover assunto: Drugs remover
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1
Encoded Combinatorial Chemistry: Synthesis and Screening of a Library of Highly Functionalized Pyrrolidines
Encoded Combinatorial Chemistry: Synthesis and Screening of a Library of Highly Functionalized Pyrrolidines
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Encoded Combinatorial Chemistry: Synthesis and Screening of a Library of Highly Functionalized Pyrrolidines

Maclean, Derek ; Schullek, John R. ; Murphy, Martin M. ; Ni, Zhi-Jie ; Gordon, Eric M. ; Gallop, Mark A.

Proceedings of the National Academy of Sciences - PNAS, 1997-04, Vol.94 (7), p.2805-2810 [Periódico revisado por pares]

United States: National Academy of Sciences of the United States of America

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2
Combinatorial drug discovery in nanoliter droplets
Combinatorial drug discovery in nanoliter droplets
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Combinatorial drug discovery in nanoliter droplets

Kulesa, Anthony ; Kehe, Jared ; Hurtado, Juan E. ; Tawde, Prianca ; Blainey, Paul C.

Proceedings of the National Academy of Sciences - PNAS, 2018-06, Vol.115 (26), p.6685-6690 [Periódico revisado por pares]

United States: National Academy of Sciences

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3
A Structure-Based Drug Discovery Paradigm
A Structure-Based Drug Discovery Paradigm
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A Structure-Based Drug Discovery Paradigm

Batool, Maria ; Ahmad, Bilal ; Choi, Sangdun

International journal of molecular sciences, 2019-06, Vol.20 (11), p.2783 [Periódico revisado por pares]

Switzerland: MDPI AG

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4
Identification of highly selective and potent histone deacetylase 3 inhibitors using click chemistry-based combinatorial fragment assembly
Identification of highly selective and potent histone deacetylase 3 inhibitors using click chemistry-based combinatorial fragment assembly
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Identification of highly selective and potent histone deacetylase 3 inhibitors using click chemistry-based combinatorial fragment assembly

Suzuki, Takayoshi ; Kasuya, Yuki ; Itoh, Yukihiro ; Ota, Yosuke ; Zhan, Peng ; Asamitsu, Kaori ; Nakagawa, Hidehiko ; Okamoto, Takashi ; Miyata, Naoki Jung, Manfred

PloS one, 2013-07, Vol.8 (7), p.e68669-e68669 [Periódico revisado por pares]

United States: Public Library of Science

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5
Total kinetic analysis reveals how combinatorial methylation patterns are established on lysines 27 and 36 of histone H3
Total kinetic analysis reveals how combinatorial methylation patterns are established on lysines 27 and 36 of histone H3
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Total kinetic analysis reveals how combinatorial methylation patterns are established on lysines 27 and 36 of histone H3

Zheng, Yupeng ; Sweet, Steve M. M ; Popovic, Relja ; Martinez-Garcia, Eva ; Tipton, Jeremiah D ; Thomas, Paul M ; Licht, Jonathan D ; Kelleher, Neil L

Proceedings of the National Academy of Sciences - PNAS, 2012-08, Vol.109 (34), p.13549-13554 [Periódico revisado por pares]

United States: National Academy of Sciences

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6
The Potential of Flavonoids for the Treatment of Neurodegenerative Diseases
The Potential of Flavonoids for the Treatment of Neurodegenerative Diseases
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The Potential of Flavonoids for the Treatment of Neurodegenerative Diseases

Maher, Pamela

International journal of molecular sciences, 2019-06, Vol.20 (12), p.3056 [Periódico revisado por pares]

Switzerland: MDPI AG

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7
Inhibitors of pantothenate synthetase of Mycobacterium tuberculosis - a medicinal chemist perspective
Inhibitors of pantothenate synthetase of Mycobacterium tuberculosis - a medicinal chemist perspective
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Inhibitors of pantothenate synthetase of Mycobacterium tuberculosis - a medicinal chemist perspective

Suresh, Amaroju ; Srinivasarao, Singireddi ; Khetmalis, Yogesh Mahadu ; Nizalapur, Shashidhar ; Sankaranarayanan, Murugesan ; Gowri Chandra Sekhar, Kondapalli Venkata

RSC advances, 2020-10, Vol.10 (61), p.37098-37115 [Periódico revisado por pares]

England: Royal Society of Chemistry

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8
Multicomponent Reaction-Assisted Drug Discovery: A Time- and Cost-Effective Green Approach Speeding Up Identification and Optimization of Anticancer Drugs
Multicomponent Reaction-Assisted Drug Discovery: A Time- and Cost-Effective Green Approach Speeding Up Identification and Optimization of Anticancer Drugs
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Multicomponent Reaction-Assisted Drug Discovery: A Time- and Cost-Effective Green Approach Speeding Up Identification and Optimization of Anticancer Drugs

Graziano, Giovanni ; Stefanachi, Angela ; Contino, Marialessandra ; Prieto-Díaz, Rubén ; Ligresti, Alessia ; Kumar, Poulami ; Scilimati, Antonio ; Sotelo, Eddy ; Leonetti, Francesco

International journal of molecular sciences, 2023-04, Vol.24 (7), p.6581 [Periódico revisado por pares]

Switzerland: MDPI AG

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9
Drug Discovery: A Historical Perspective
Drug Discovery: A Historical Perspective
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Drug Discovery: A Historical Perspective

Drews, Jürgen

Science (American Association for the Advancement of Science), 2000-03, Vol.287 (5460), p.1960-1964 [Periódico revisado por pares]

Washington, DC: American Society for the Advancement of Science

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10
Virtual screening, identification and in vitro testing of novel inhibitors of O-acetyl-L-serine sulfhydrylase of Entamoeba histolytica
Virtual screening, identification and in vitro testing of novel inhibitors of O-acetyl-L-serine sulfhydrylase of Entamoeba histolytica
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Virtual screening, identification and in vitro testing of novel inhibitors of O-acetyl-L-serine sulfhydrylase of Entamoeba histolytica

Nagpal, Isha ; Raj, Isha ; Subbarao, Naidu ; Gourinath, Samudrala Bogyo, Matthew

PloS one, 2012-02, Vol.7 (2), p.e30305 [Periódico revisado por pares]

United States: Public Library of Science

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