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Effect of multiple micronutrient-fortified bouillon on micronutrient status among women and children in the Northern Region of Ghana: Protocol for the Condiment Micronutrient Innovation Trial

Engle-Stone, Reina ; Wessells, K Ryan ; Haskell, Marjorie J ; Kumordzie, Sika M ; Arnold, Charles D ; Davis, Jennie N ; Becher, Emily R ; Fuseini, Ahmed D ; Nyaaba, Kania W ; Tan, Xiuping ; Adams, Katherine P ; Lietz, Georg ; Vosti, Stephen A ; Adu-Afarwuah, Seth

PloS one, 2024-05, Vol.19 (5), p.e0302968 [Periódico revisado por pares]

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Effect of multiple micronutrient-fortified bouillon on micronutrient status among women and children in the Northern Region of Ghana: Protocol for the Condiment Micronutrient Innovation Trial
Autor: Engle-Stone, Reina ; Wessells, K Ryan ; Haskell, Marjorie J ; Kumordzie, Sika M ; Arnold, Charles D ; Davis, Jennie N ; Becher, Emily R ; Fuseini, Ahmed D ; Nyaaba, Kania W ; Tan, Xiuping ; Adams, Katherine P ; Lietz, Georg ; Vosti, Stephen A ; Adu-Afarwuah, Seth
Assuntos: Anemia ; Children ; Clinical trials ; Enriched foods ; Folic acid ; Food and nutrition ; Food research ; Glycosylated hemoglobin ; Health aspects ; Innovations ; Malaria ; Patient outcomes ; Pediatric research ; Pregnant women ; Soups ; Vitamin A ; Women
É parte de: PloS one, 2024-05, Vol.19 (5), p.e0302968
Descrição: Micronutrient deficiencies are prevalent in West Africa, particularly among women of reproductive age (WRA) and young children. Bouillon is a promising food fortification vehicle due to its widespread consumption. This study aims to evaluate the impact of multiple micronutrient-fortified bouillon cubes, compared to control bouillon cubes (fortified with iodine only), on micronutrient status and hemoglobin concentrations among lactating and non-lactating WRA and young children in northern Ghana. This randomized, controlled doubly-masked trial will be conducted in the Kumbungu and Tolon districts in the Northern Region of Ghana, where prior data indicate multiple micronutrient deficiencies are common. Participants will be: 1) non-pregnant non-lactating WRA (15-49 y), 2) children 2-5 y, and 3) non-pregnant lactating women 4-18 months postpartum. Eligible participants will be randomly assigned to receive household rations of one of two types of bouillon cubes: 1) a multiple micronutrient-fortified bouillon cube containing vitamin A, folic acid, vitamin B12, iron, zinc, and iodine, or 2) a control cube containing iodine only. Evidence from this study will inform discussions about bouillon fortification in Ghana and West Africa.
Editor: Public Library of Science
Idioma: Inglês

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Effect of multiple micronutrient-fortified bouillon on micronutrient status among women and children in the Northern Region of Ghana: Protocol for the Condiment Micronutrient Innovation Trial

Engle-Stone, Reina ; Wessells, K Ryan ; Haskell, Marjorie J ; Kumordzie, Sika M ; Arnold, Charles D ; Davis, Jennie N ; Becher, Emily R ; Fuseini, Ahmed D ; Nyaaba, Kania W ; Tan, Xiuping ; Adams, Katherine P ; Lietz, Georg ; Vosti, Stephen A ; Adu-Afarwuah, Seth

Public Library of Science

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