skip to main content
Idioma:
Primo Search
Clear Search Box
Search in: Busca Geral
Busca Avançada
Busca por Índices
Tipo de recurso Mostra resultados com: Mostra resultados com: Índice

Effect of a soybean fat emulsion on refractory pruritus cutanea in patients on chronic hemodialysis therapy

Nagake, Yoshio ; Makino, Hirofumi ; Kumagai, Isao ; Haramoto, Toshinori ; Awata, Toshie ; Teraoka, Akira ; Ota, Zensuke

Journal of Japanese Society for Dialysis Therapy, 1993/04/28, Vol.26(4), pp.503-506

The Japanese Society for Dialysis Therapy

Texto completo disponível

Citações Citado por
  • Título:
    Effect of a soybean fat emulsion on refractory pruritus cutanea in patients on chronic hemodialysis therapy
  • Autor: Nagake, Yoshio ; Makino, Hirofumi ; Kumagai, Isao ; Haramoto, Toshinori ; Awata, Toshie ; Teraoka, Akira ; Ota, Zensuke
  • É parte de: Journal of Japanese Society for Dialysis Therapy, 1993/04/28, Vol.26(4), pp.503-506
  • Descrição: Pruritus cutanae, a complication often encountered in patients on chronic hemodialysis (HD) therapy, remains to be fully elucidated in terms of the underlying pathogenetic mechanisms and the development of appropriate therapy for this morbid condition. Seven chronic HD patients with refractory pruritus entered the present study according to our strictly defined criteria for patient inclusion and received a soybean oil emulsion given via the HD circuit's venous side twice or three times per week for 4 to 8 weeks. Five patients (71.4%) responded to treatment with resolution or improvement of both skin dryness and itching. Monitoring of laboratory parameters revealed no significant differences between pre-and post-medication values. No adverse drug reactions occurred. However, skin dryness and itching reappeared in 4 of the patients 4 weeks after withdrawal of the drug. Readministration of the drug was effective in all 4 patients with this recurrence. In conclusion, treatment with a soybean oil emulsion was confirmed to be effective and safe in patients manifesting uremic pruritus when given to those with strict indications for the medication. The mechanism of action of this drug remains to be explained, but we anticipate that this will lead to the successful development of a more effective and even safer agent as well as to certain innovations in HD procedures.
  • Editor: The Japanese Society for Dialysis Therapy
  • Idioma: Japonês
Voltar para lista de resultados

  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

Buscando em bases de dados remotas. Favor aguardar.