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Second primary malignancy of the aerodigestive tract in patients treated for cancer of the oral cavity and larynx

Lin, Karen ; Patel, Snehal G. ; Chu, Pen Yuan ; Matsuo, Jeannette M. S. ; Singh, Bhuvanesh ; Wong, Richard J. ; Kraus, Dennis H. ; Shaha, Ashok R. ; Shah, Jatin P. ; Boyle, Jay O.

Head & neck, 2005-12, Vol.27 (12), p.1042-1048 [Periódico revisado por pares]

Hoboken: Wiley Subscription Services, Inc., A Wiley Company

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Título:
Second primary malignancy of the aerodigestive tract in patients treated for cancer of the oral cavity and larynx
Autor: Lin, Karen ; Patel, Snehal G. ; Chu, Pen Yuan ; Matsuo, Jeannette M. S. ; Singh, Bhuvanesh ; Wong, Richard J. ; Kraus, Dennis H. ; Shaha, Ashok R. ; Shah, Jatin P. ; Boyle, Jay O.
Assuntos: Adolescent ; Adult ; Aged ; Aged, 80 and over ; Alcohol Drinking - adverse effects ; Biological and medical sciences ; Carcinoma, Squamous Cell - epidemiology ; Carcinoma, Squamous Cell - pathology ; Carcinoma, Squamous Cell - therapy ; Esophageal Neoplasms - epidemiology ; Esophageal Neoplasms - pathology ; Female ; Follow-Up Studies ; Head and Neck Neoplasms - epidemiology ; Head and Neck Neoplasms - pathology ; Head and Neck Neoplasms - therapy ; Humans ; Incidence ; Lung Neoplasms - epidemiology ; Lung Neoplasms - pathology ; Male ; Medical sciences ; Middle Aged ; neoplasms ; Neoplasms, Second Primary - epidemiology ; Neoplasms, Second Primary - pathology ; neoplasms, second primary/therapy ; New York - epidemiology ; Otorhinolaryngology. Stomatology ; second primary/epidemiology ; second primary/therapy ; Smoking - adverse effects ; Survival Analysis ; Tumors ; Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology
É parte de: Head & neck, 2005-12, Vol.27 (12), p.1042-1048
Notas: ark:/67375/WNG-P2NF3STN-P
istex:8D69073D469D47495987956D75B73B51190E0CA3
ArticleID:HED20272
Presented at the 6th International Conference on Head and Neck Cancer, Washington, DC, August 8, 2004
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: Background. We aimed to identify patterns and predictors of second primary malignancy (SPM) of the aerodigestive tract (SPMADT) in patients with squamous cell carcinoma of the oral cavity (SCCOC) and larynx (SCCL). Methods. One thousand two hundred fifty‐seven patients from two existing databases were studied: 595 with SCCOC (1986–1995) and 662 with SCCL (1984–1998). The primary endpoint of interest was development of SPMADT, defined as a second primary neoplasm of the head and neck, esophagus, or lung. Results. The 5‐year SPMADT rate was 8% in the SCCL versus 10% in the SCCOC subgroup. Lung SPM was more common in the SCCL group; head and neck SPM was more common in the SCCOC group. Smokers had a fivefold increased risk, whereas alcohol use was associated with a twofold increased risk of SPMADT. Conclusions. The rates of SPMADT after treatment of SCCOC and SCCL are comparable, but the patterns are different. Smoking and alcohol use are independent predictors of SPMADT development. © 2005 Wiley Periodicals, Inc. Head Neck 27: XXX–XXX, 2005
Editor: Hoboken: Wiley Subscription Services, Inc., A Wiley Company
Idioma: Inglês

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Second primary malignancy of the aerodigestive tract in patients treated for cancer of the oral cavity and larynx

Lin, Karen ; Patel, Snehal G. ; Chu, Pen Yuan ; Matsuo, Jeannette M. S. ; Singh, Bhuvanesh ; Wong, Richard J. ; Kraus, Dennis H. ; Shaha, Ashok R. ; Shah, Jatin P. ; Boyle, Jay O.

Hoboken: Wiley Subscription Services, Inc., A Wiley Company

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