Idioma:

Bacterial cellulose membrane used as biological dressings on third-degree burns in rats

Brassolatti, Patricia ; Kido, Hueliton Wilian ; Bossini, Paulo Sérgio ; Gabbai-Armelin, Paulo R ; Otterço, Albaiza Nicoletti ; Almeida-Lopes, Luciana ; Zanardi, Lisinéia Maria ; Napolitano, Marcos Aurélio ; de Avó, Lucimar Retto da Silva ; Forato, Lucimara Aparecida ; Araújo-Moreira, Fernando M ; Parizotto, Nivaldo Antonio

Bio-medical materials and engineering, 2018-01, Vol.29 (1), p.29-42 [Periódico revisado por pares]

Netherlands: IOS Press BV

Texto completo disponível

Citações Citado por

Enviar para

Título:
Bacterial cellulose membrane used as biological dressings on third-degree burns in rats
Autor: Brassolatti, Patricia ; Kido, Hueliton Wilian ; Bossini, Paulo Sérgio ; Gabbai-Armelin, Paulo R ; Otterço, Albaiza Nicoletti ; Almeida-Lopes, Luciana ; Zanardi, Lisinéia Maria ; Napolitano, Marcos Aurélio ; de Avó, Lucimar Retto da Silva ; Forato, Lucimara Aparecida ; Araújo-Moreira, Fernando M ; Parizotto, Nivaldo Antonio
Assuntos: Appendages ; Bacteria ; Biomaterials ; Biomedical materials ; Burns ; Cellulose ; Chemical industry ; Collagen ; Cyclooxygenase-2 ; Dressings ; Enrichment ; Gelatinase B ; Health risks ; Inflammation ; Iron ; Lidocaine ; Morbidity ; Neck ; Rats ; Skin ; Skin injuries ; Soldering ; Statistical analysis ; Statistical methods ; Studies ; Wound healing
É parte de: Bio-medical materials and engineering, 2018-01, Vol.29 (1), p.29-42
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: Burn injuries represent a high risk of morbidity and mortality. The wound healing process is complex and requires the participation of different types of cells. Therefore, new biomaterials, which innovate the wound healing process, are being investigated. The aim of this study was to investigate the use of bacterial cellulose both in its pure state and enriched with lidocaine in full-thickness burns in rats. Thirty rats (Wistar) (260 ± 20 gramas) divided into control group (CG), bacterial cellulose membrane group (MG) and bacterial cellulose membrane enriched with lidocaine group (MLG) were used. The burns were induced using a 150°C heated soldering iron, held on the animal neck for 10 seconds. The biomaterial was applied immediately after injury and skin samples were collected on the tenth day of the treatment. The level of significance of p⩽0.05 was used for the conclusion of the statistical analysis. The groups treated with the biomaterials, a histological pattern compatible with a more advanced repair stage showing skin appendages, mild inflammatory infiltrate, better collagen fiber organization and mild immunostaining COX-2 and MMP-9 was observed, when compared to the control group that did not receive any type of treatment. Thus, was concluded that the bacterial cellulose-based biomaterial both in its pure state and enriched with lidocaine optimizing the full-thickness burn wound healing in rats.
Editor: Netherlands: IOS Press BV
Idioma: Inglês

Links

View this record in MEDLINE/PubMed

Voltar para lista de resultados

Realização: Logos de Redes Sociais:

Bacterial cellulose membrane used as biological dressings on third-degree burns in rats

Netherlands: IOS Press BV

Buscando em bases de dados remotas. Favor aguardar.