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Biofilm in Chronic Sinusitis with Nasal Polyps: Pilot study

Pinto Bezerra, Thiago Freire ; de Melo Pádua, Francini Grecco ; Ogawa, Allex Itar ; Santiago Gebrim, Eloisa Maria Mello ; Nascimento Saldiva, Paulo Hilário ; Voegels, Richard Louis

Brazilian journal of otorhinolaryngology, 2009-11, Vol.75 (6), p.788-793 [Periódico revisado por pares]

Brazil: Elsevier Editora Ltda

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Título:
Biofilm in Chronic Sinusitis with Nasal Polyps: Pilot study
Autor: Pinto Bezerra, Thiago Freire ; de Melo Pádua, Francini Grecco ; Ogawa, Allex Itar ; Santiago Gebrim, Eloisa Maria Mello ; Nascimento Saldiva, Paulo Hilário ; Voegels, Richard Louis
Assuntos: Adult ; Biofilms ; Chronic Disease ; Cohort Studies ; Cross-Sectional Studies ; Female ; Humans ; Male ; Microscopy, Electron, Scanning ; Middle Aged ; Nasal Mucosa - microbiology ; Nasal Mucosa - ultrastructure ; nasal polyps ; Nasal Polyps - microbiology ; Nasal Polyps - surgery ; Original ; Pilot Projects ; Reproducibility of Results ; Rhinitis - microbiology ; Rhinitis - surgery ; sinusitis ; Sinusitis - microbiology ; Sinusitis - surgery
É parte de: Brazilian journal of otorhinolaryngology, 2009-11, Vol.75 (6), p.788-793
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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Descrição: Chronic rhinosinusitis' pathogenesis is not completely established and there are some explanations for this disease, such as osteitis, superantigens, fungal-mediated hypersensitivity and, more recently, biofilms. There are no reports in Portuguese about biofilms in chronic rhinosinusitis. To reproduce a method for visualization of biofilms in patients with chronic rhinosinusitis and nasal polyps. Samples of ethmoid bulla of nine patients with chronic rhinosinusitis with nasal polyps without response to clinical treatment who underwent surgery were analyzed with scanning electron microscopy to evidence bacterial biofilms. A contemporary cross-sectional cohort study In 55.56% (5/9) of the patients we observed biofilms by seeing three-dimensional structures, spherical structures surrounded by an amorphous matrix and water-channels. We reproduced a method for visualization of bacterial biofilms by scanning electron microscopy and evidenced its presence in chronic rhinosinusitis with nasal polyps.
Editor: Brazil: Elsevier Editora Ltda
Idioma: Inglês

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Biofilm in Chronic Sinusitis with Nasal Polyps: Pilot study

Pinto Bezerra, Thiago Freire ; de Melo Pádua, Francini Grecco ; Ogawa, Allex Itar ; Santiago Gebrim, Eloisa Maria Mello ; Nascimento Saldiva, Paulo Hilário ; Voegels, Richard Louis

Brazil: Elsevier Editora Ltda

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