Idioma:

A novel hepadnavirus in domestic dogs

Diakoudi, Georgia ; Capozza, Paolo ; Lanave, Gianvito ; Pellegrini, Francesco ; Di Martino, Barbara ; Elia, Gabriella ; Decaro, Nicola ; Camero, Michele ; Ghergo, Paola ; Stasi, Fabio ; Cavalli, Alessandra ; Tempesta, Maria ; Barrs, Vanessa R ; Beatty, Julia ; Bányai, Krisztián ; Catella, Cristiana ; Lucente, Maria S ; Buonavoglia, Alessio ; Fusco, Giovanna ; Martella, Vito

Scientific reports, 2022-02, Vol.12 (1), p.2864-2864, Article 2864 [Periódico revisado por pares]

England: Nature Publishing Group

Texto completo disponível

Citações Citado por

Enviar para

Título:
A novel hepadnavirus in domestic dogs
Autor: Diakoudi, Georgia ; Capozza, Paolo ; Lanave, Gianvito ; Pellegrini, Francesco ; Di Martino, Barbara ; Elia, Gabriella ; Decaro, Nicola ; Camero, Michele ; Ghergo, Paola ; Stasi, Fabio ; Cavalli, Alessandra ; Tempesta, Maria ; Barrs, Vanessa R ; Beatty, Julia ; Bányai, Krisztián ; Catella, Cristiana ; Lucente, Maria S ; Buonavoglia, Alessio ; Fusco, Giovanna ; Martella, Vito
Assuntos: Animals ; DNA, Viral - blood ; DNA, Viral - isolation & purification ; Dogs ; Dogs - virology ; Genome, Viral - genetics ; Genomes ; Hepadnaviridae - genetics ; Hepadnaviridae - isolation & purification ; Hepatitis B ; Hepatocellular carcinoma ; Liver cancer ; Liver diseases ; Phylogeny ; Public health ; Whole Genome Sequencing
É parte de: Scientific reports, 2022-02, Vol.12 (1), p.2864-2864, Article 2864
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: Hepadnaviruses have been identified in several animal species. The hepadnavirus prototype, human hepatitis B virus (HBV), is a major public health problem associated with chronic liver diseases and hepatocellular carcinoma. Recently, a novel hepadnavirus, similar to HBV, was identified in domestic cats. Since several pathogens can be shared between cats and dogs, we hypothesized that dogs could also harbor hepadnaviruses and we tested a collection of canine sera with multiple molecular strategies. Overall, hepadnavirus DNA was identified in 6.3% (40/635) of canine serum samples, although the viral load in positive sera was low (geometric mean of 2.70 × 10 genome copies per mL, range min 1.36 × 10 -max 4.03 × 10 genome copies per mL). On genome sequencing, the canine hepadnaviruses revealed high nucleotide identity (about 98%) and similar organization to the domestic cat hepadnavirus. Altered hepatic markers were found in hepadnavirus-positive dogs, although the role of hepadnavirus in canine health remains to be elucidated.
Editor: England: Nature Publishing Group
Idioma: Inglês

Links

View this record in MEDLINE/PubMed

Voltar para lista de resultados

Realização: Logos de Redes Sociais:

A novel hepadnavirus in domestic dogs

England: Nature Publishing Group

Buscando em bases de dados remotas. Favor aguardar.