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The Presence of Ribonucleotides in Mature Closed-Circular Mitochondrial DNA

Grossman, Lawrence I. ; Watson, Robert ; Vinograd, Jerome

Proceedings of the National Academy of Sciences - PNAS, 1973-12, Vol.70 (12), p.3339-3343 [Periódico revisado por pares]

United States: National Academy of Sciences of the United States of America

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Título:
The Presence of Ribonucleotides in Mature Closed-Circular Mitochondrial DNA
Autor: Grossman, Lawrence I. ; Watson, Robert ; Vinograd, Jerome
Assuntos: Alkalies ; Alkaline Phosphatase - metabolism ; Animals ; Bacteriophages ; Biological Sciences: Biochemistry ; Centrifugation ; Centrifugation, Density Gradient ; DNA ; DNA, Circular - analysis ; DNA, Circular - isolation & purification ; DNA, Circular - metabolism ; DNA, Mitochondrial - analysis ; DNA, Mitochondrial - isolation & purification ; DNA, Mitochondrial - metabolism ; Enzymes ; Female ; Haplorhini ; HeLa Cells ; Humans ; Hydrogen-Ion Concentration ; Hydrolysis ; Kidney ; Kinetics ; Mitochondrial DNA ; Molecules ; Phosphorus Radioisotopes ; Ribonucleases - metabolism ; Ribonucleotides ; RNA ; RNA - metabolism ; Temperature ; Tritium
É parte de: Proceedings of the National Academy of Sciences - PNAS, 1973-12, Vol.70 (12), p.3339-3343
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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Descrição: Mitochondrial DNA from mouse and HeLa cells is nicked by alkali and chick-embryo ribonuclease H. It has been concluded that ribonucleotides are present in the closed-circular duplex. A comparative study of the scission rates at pH 13.0 of RNA and of mitochondrial DNAs indicates that there are no more than 10 ribonucleotides in the major fraction of the mitochondrial DNAs.
Editor: United States: National Academy of Sciences of the United States of America
Idioma: Inglês

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The Presence of Ribonucleotides in Mature Closed-Circular Mitochondrial DNA

Grossman, Lawrence I. ; Watson, Robert ; Vinograd, Jerome

United States: National Academy of Sciences of the United States of America

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