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Molecular Identification of Aspergillus Species Collected for the Transplant-Associated Infection Surveillance Network

Balajee, S. Arunmozhi ; Kano, Rui ; Baddley, John W ; Moser, Stephen A ; Marr, Kieren A ; Alexander, Barbara D ; Andes, David ; Kontoyiannis, Dimitrios P ; Perrone, Giancarlo ; Peterson, Stephen ; Brandt, Mary E ; Pappas, Peter G ; Chiller, Tom

Journal of Clinical Microbiology, 2009-10, Vol.47 (10), p.3138-3141 [Periódico revisado por pares]

Washington, DC: American Society for Microbiology

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Título:
Molecular Identification of Aspergillus Species Collected for the Transplant-Associated Infection Surveillance Network
Autor: Balajee, S. Arunmozhi ; Kano, Rui ; Baddley, John W ; Moser, Stephen A ; Marr, Kieren A ; Alexander, Barbara D ; Andes, David ; Kontoyiannis, Dimitrios P ; Perrone, Giancarlo ; Peterson, Stephen ; Brandt, Mary E ; Pappas, Peter G ; Chiller, Tom
Assuntos: Antifungal Agents - pharmacology ; antimicrobial agents ; aspergillosis ; Aspergillosis - microbiology ; Aspergillus ; Aspergillus - classification ; Aspergillus - genetics ; Aspergillus - isolation & purification ; Aspergillus flavus ; Aspergillus fumigatus ; Aspergillus niger ; Aspergillus tubingensis ; Biological and medical sciences ; DNA, Fungal - chemistry ; DNA, Fungal - genetics ; DNA, Ribosomal Spacer - chemistry ; DNA, Ribosomal Spacer - genetics ; etiology ; Fundamental and applied biological sciences. Psychology ; genes ; human diseases ; Humans ; Immunocompromised Host ; internal transcribed spacers ; Microbial Sensitivity Tests ; Microbiology ; minimum inhibitory concentration ; Miscellaneous ; Mycology ; nucleotide sequences ; organ transplantation ; pathogen identification ; patients ; Sequence Analysis, DNA ; Transplant-Associated Infection Surveillance Network ; Transplantation - adverse effects ; tubulin ; Tubulin - genetics
É parte de: Journal of Clinical Microbiology, 2009-10, Vol.47 (10), p.3138-3141
Notas: http://hdl.handle.net/10113/36284
http://dx.doi.org/10.1128/JCM.01070-09
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Corresponding author. Mailing address: Mycotic Diseases Branch, Centers for Disease Control and Prevention, Mail Stop G 11, 1600 Clifton Road, Atlanta, GA 30333. Phone: (404) 639-3337. Fax: (404) 639-3546. E-mail: fir3@cdc.gov
Descrição: A large aggregate collection of clinical isolates of aspergilli (n = 218) from transplant patients with proven or probable invasive aspergillosis was available from the Transplant-Associated Infection Surveillance Network, a 6-year prospective surveillance study. To determine the Aspergillus species distribution in this collection, isolates were subjected to comparative sequence analyses by use of the internal transcribed spacer and β-tubulin regions. Aspergillus fumigatus was the predominant species recovered, followed by A. flavus and A. niger. Several newly described species were identified, including A. lentulus and A. calidoustus; both species had high in vitro MICs to multiple antifungal drugs. Aspergillus tubingensis, a member of the A. niger species complex, is described from clinical specimens; all A. tubingensis isolates had low in vitro MICs to antifungal drugs.
Editor: Washington, DC: American Society for Microbiology
Idioma: Inglês

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Molecular Identification of Aspergillus Species Collected for the Transplant-Associated Infection Surveillance Network

Balajee, S. Arunmozhi ; Kano, Rui ; Baddley, John W ; Moser, Stephen A ; Marr, Kieren A ; Alexander, Barbara D ; Andes, David ; Kontoyiannis, Dimitrios P ; Perrone, Giancarlo ; Peterson, Stephen ; Brandt, Mary E ; Pappas, Peter G ; Chiller, Tom

Washington, DC: American Society for Microbiology

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