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Biginelli reaction of β-ketophosphonates, aromatic or aliphatic aldehydes and urea derivatives

Popovics-Tóth, Nóra ; Tajti, Ádám ; Bálint, Erika

Phosphorus, Sulfur, and Silicon and the Related Elements: ICPC-23: 23rd International Conference on Phosphorus Chemistry; Guest Editors:Professor Jozef Drabowicz; Professor Piotr Kiełbasiński and Professor Tomasz Cierpiał, 2022, Vol.197 (5-6), p.597-598

Taylor & Francis

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  • Título:
    Biginelli reaction of β-ketophosphonates, aromatic or aliphatic aldehydes and urea derivatives
  • Autor: Popovics-Tóth, Nóra ; Tajti, Ádám ; Bálint, Erika
  • Assuntos: 3,4-Dihydropyrimidin-2(1H)-one phosphonates ; Biginelli reaction ; microwave ; multicomponent reaction
  • É parte de: Phosphorus, Sulfur, and Silicon and the Related Elements: ICPC-23: 23rd International Conference on Phosphorus Chemistry; Guest Editors:Professor Jozef Drabowicz; Professor Piotr Kiełbasiński and Professor Tomasz Cierpiał, 2022, Vol.197 (5-6), p.597-598
  • Descrição: The synthesis of 3,4-dihydropyrimidin-2(1H)-one phosphonates by the Biginelli reaction of β-ketophosphonates, aldehydes and urea derivatives was studied under microwave conditions. The molar ratio of the starting materials, temperature and reaction time was changed to find the optimal parameters. An efficient zinc-triflate-catalyzed solvent-free method was developed. The condensation was extended and carried out with different β-ketophosphonates, aromatic or aliphatic aldehydes and urea derivatives.
  • Editor: Taylor & Francis
  • Idioma: Inglês
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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