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Preliminary study of breastfeeding and bacterial adhesion to uroepithelial cells

Coppa, G.V. ; Gabrielli, O. ; Giorgi, P. ; Catassi, C. ; Montanari, M.P. ; Varaldo, P.E. ; Nichols, B.L.

The Lancet (British edition), 1990-03, Vol.335 (8689), p.569-571 [Periódico revisado por pares]

London: Elsevier Ltd

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Título:
Preliminary study of breastfeeding and bacterial adhesion to uroepithelial cells
Autor: Coppa, G.V. ; Gabrielli, O. ; Giorgi, P. ; Catassi, C. ; Montanari, M.P. ; Varaldo, P.E. ; Nichols, B.L.
Assuntos: Adhesion ; Adhesion tests ; Adolescent ; Adult ; Babies ; Bacteria ; Bacterial Adhesion - drug effects ; Bacterial Adhesion - physiology ; Biological and medical sciences ; Breast Feeding ; Breast milk ; Breastfeeding & lactation ; Colostrum ; E coli ; Epithelial Cells ; Epithelium - physiology ; Escherichia coli - physiology ; Female ; Gynecology. Andrology. Obstetrics ; High performance liquid chromatography ; Humans ; In Vitro Techniques ; Infant, Newborn ; Infections ; Liquid chromatography ; Medical sciences ; Milk ; Milk, Human - analysis ; Milk, Human - immunology ; Nursing ; Oligosaccharides ; Oligosaccharides - analysis ; Oligosaccharides - pharmacology ; Oligosaccharides - urine ; Urinary tract ; Urinary tract diseases ; Urinary tract infections ; Urinary Tract Infections - prevention & control ; Urine ; Urogenital system
É parte de: The Lancet (British edition), 1990-03, Vol.335 (8689), p.569-571
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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Descrição: The oligosaccharide content of breast-milk and urine from ten nursing mothers and their babies, collected 30 days after delivery, was analysed by thin-layer and high-performance liquid chromatography. Each woman's milk and urinary oligosaccharide profiles were very similar, and the pattern of oligosaccharides excreted by her infant was also strongly correlated with that of her milk. The babies excreted 300-500 mg/day oligosaccharides and the mothers 500-800 mg/day. The effect of oligosaccharide fractions from a 500 ml pool of colostrum on bacterial adhesion to uroepithelial cells was tested on a strain of Escherichia coli isolated from an infant with urinary tract infection. The high-molecularweight sialylated oligosaccharides had no effect but neutral oligosaccharides caused inhibition of bacterial adhesion which rose as the size of the oligosaccharides decreased. These findings suggest that breastfeeding may have a preventive effect on urinary tract infection in both mother and infant.
Editor: London: Elsevier Ltd
Idioma: Inglês

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Preliminary study of breastfeeding and bacterial adhesion to uroepithelial cells

Coppa, G.V. ; Gabrielli, O. ; Giorgi, P. ; Catassi, C. ; Montanari, M.P. ; Varaldo, P.E. ; Nichols, B.L.

London: Elsevier Ltd

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