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A case of advanced colon cancer with peritoneal dissemination effectively treated with modified FOLFOX6 chemotherapy

Tanaka, Kazumi ; Hirai, Keitaro ; Ogawa, Hiroomi ; Toya, Hiroyuki ; Totsuka, Osamu ; Yoshinari, Daisuke ; Sunose, Yutaka ; Takeyoshi, Izumi

Gan to kagaku ryoho, 2012-06, Vol.39 (6), p.993-995 [Periódico revisado por pares]

Japan

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Título:
A case of advanced colon cancer with peritoneal dissemination effectively treated with modified FOLFOX6 chemotherapy
Autor: Tanaka, Kazumi ; Hirai, Keitaro ; Ogawa, Hiroomi ; Toya, Hiroyuki ; Totsuka, Osamu ; Yoshinari, Daisuke ; Sunose, Yutaka ; Takeyoshi, Izumi
Assuntos: Antineoplastic Combined Chemotherapy Protocols - therapeutic use ; Colonic Neoplasms - drug therapy ; Colonic Neoplasms - pathology ; Fatal Outcome ; Female ; Fluorouracil - therapeutic use ; Humans ; Leucovorin - therapeutic use ; Middle Aged ; Neoplasm Grading ; Organoplatinum Compounds - therapeutic use ; Ovarian Neoplasms - drug therapy ; Ovarian Neoplasms - secondary ; Peritoneal Neoplasms - drug therapy ; Peritoneal Neoplasms - secondary
É parte de: Gan to kagaku ryoho, 2012-06, Vol.39 (6), p.993-995
Notas: ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ObjectType-Report-3
ObjectType-Case Study-4
Descrição: A 50-year-old woman was diagnosed with ascending colon cancer with bilateral ovarian metastases, carcinomatous peritonitis, and carcinomatous pleurisy. Nine courses of mFOLFOX6 treatment resulted in the disappearance of her ascites and pleural effusion and a marked decrease in her serum CEA and CA19-9 levels. Additionally, the primary tumor and ovarian metastases became smaller. Therefore, a right hemicolectomy with D3 lymph node dissection, total hysterectomy, and bilateral salpingo-oophorectomy were performed. Postoperatively, we changed the chemotherapy from mFOLFOX6 to bevacizumab+FOLFIRI because the patient had an allergic reaction to oxaliplatin, and we suspected lung metastasis. Because the lung metastasis grew after ten courses of bevacizumab+FOLFIRI, we changed to cetuximab+FOLFIRI. Unfortunately, 28 months after her diagnosis, the patient died of carcinomatous pleurisy.
Editor: Japan
Idioma: Japonês

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A case of advanced colon cancer with peritoneal dissemination effectively treated with modified FOLFOX6 chemotherapy

Tanaka, Kazumi ; Hirai, Keitaro ; Ogawa, Hiroomi ; Toya, Hiroyuki ; Totsuka, Osamu ; Yoshinari, Daisuke ; Sunose, Yutaka ; Takeyoshi, Izumi

Japan

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