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Phase Ib study of the MEK inhibitor cobimetinib (GDC-0973) in combination with the PI3K inhibitor pictilisib (GDC-0941) in patients with advanced solid tumors
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Phase Ib study of the MEK inhibitor cobimetinib (GDC-0973) in combination with the PI3K inhibitor pictilisib (GDC-0941) in patients with advanced solid tumors

Shapiro, Geoffrey I. ; LoRusso, Patricia ; Kwak, Eunice ; Pandya, Susan ; Rudin, Charles M. ; Kurkjian, Carla ; Cleary, James M. ; Pilat, Mary Jo ; Jones, Suzanne ; de Crespigny, Alex ; Fredrickson, Jill ; Musib, Luna ; Yan, Yibing ; Wongchenko, Matthew ; Hsieh, Hsin-Ju ; Gates, Mary R. ; Chan, Iris T. ; Bendell, Johanna

Investigational new drugs, 2020-04, Vol.38 (2), p.419-432 [Periódico revisado por pares]

New York: Springer US

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2
A phase Ib open-label dose escalation study of the safety, pharmacokinetics, and pharmacodynamics of cobimetinib (GDC-0973) and ipatasertib (GDC-0068) in patients with locally advanced or metastatic solid tumors
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A phase Ib open-label dose escalation study of the safety, pharmacokinetics, and pharmacodynamics of cobimetinib (GDC-0973) and ipatasertib (GDC-0068) in patients with locally advanced or metastatic solid tumors

Shapiro, Geoffrey I. ; LoRusso, Patricia ; Cho, Daniel C. ; Musib, Luna ; Yan, Yibing ; Wongchenko, Matthew ; Chang, Ilsung ; Patel, Premal ; Chan, Iris T. ; Sanabria-Bohorquez, Sandra ; Meng, Raymond D. ; Bendell, Johanna C.

Investigational new drugs, 2021-02, Vol.39 (1), p.163-174 [Periódico revisado por pares]

New York: Springer US

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3
A phase I study of VS-6063, a second-generation focal adhesion kinase inhibitor, in patients with advanced solid tumors
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Artigo
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A phase I study of VS-6063, a second-generation focal adhesion kinase inhibitor, in patients with advanced solid tumors

Jones, Suzanne F. ; Siu, Lillian L. ; Bendell, Johanna C. ; Cleary, James M. ; Razak, Albiruni R. A. ; Infante, Jeffrey R. ; Pandya, Shuchi S. ; Bedard, Philippe L. ; Pierce, Kristen J. ; Houk, Brett ; Roberts, W. Gregory ; Shreeve, S. Martin ; Shapiro, Geoffrey I.

Investigational new drugs, 2015-10, Vol.33 (5), p.1100-1107 [Periódico revisado por pares]

New York: Springer US

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