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Refinado por: Base de dados/Biblioteca: Directory of Open Access Journals (DOAJ) remover Base de dados/Biblioteca: PMC (PubMed Central) remover assunto: Epithelial-Mesenchymal Transition remover nível superior: Recursos Online remover
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P2Y2 Receptor and EGFR Cooperate to Promote Prostate Cancer Cell Invasion via ERK1/2 Pathway

Li, Wei-Hua ; Qiu, Ying ; Zhang, Hong-Quan ; Tian, Xin-Xia ; Fang, Wei-Gang

PLoS ONE, July 16, 2015, Vol.10(7) [Periódico revisado por pares]

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Periostin Contributes to the Acquisition of Multipotent Stem Cell-Like Properties in Human Mammary Epithelial Cells and Breast Cancer Cells.(Research Article)

Wang, Xiaowei ; Liu, Jia ; Wang, Zhe ; Huang, Yangmei ; Liu, Weiping ; Zhu, Xiao ; Cai, Yao ; Fang, Xiaoguang ; Lin, Shuyong ; Yuan, Li ; Ouyang, Gaoliang

PLoS ONE, August 29, 2013, Vol.8(8), p.e72962 [Periódico revisado por pares]

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MED30 Regulates the Proliferation and Motility of Gastric Cancer Cells

Lee, Yong Joo ; Han, Myoung-Eun ; Baek, Su-Jin ; Kim, Seon-Young ; Oh, Sae-Ock

PLoS ONE, June 25, 2015, Vol.10(6) [Periódico revisado por pares]

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The quorum sensing peptides PhrG, CSP and EDF promote angiogenesis and invasion of breast cancer cells in vitro

De Spiegeleer, Bart ; Verbeke, Frederick ; D'Hondt, Matthias ; Hendrix, An ; Van De Wiele, Christophe ; Burvenich, Christian ; Peremans, Kathelijne ; De Wever, Olivier ; Bracke, Marc ; Wynendaele, Evelien

PLOS ONE, 2015 [Periódico revisado por pares]

2015

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CRF2 signaling is a novel regulator of cellular adhesion and migration in colorectal cancer cells

Ducarouge, Benjamin ; Pelissier-Rota, Marjolaine ; Lainé, Michèle ; Cristina, Nadine ; Vachez, Yvan ; Scoazec, Jean-Yves ; Bonaz, Bruno ; Jacquier-Sarlin, Muriel Sinniger, Valérie (Editor)

PLoS ONE, 2013, Vol.8(11), p.e79335 [Periódico revisado por pares]

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Imaging the Impact of Chemically Inducible Proteins on Cellular Dynamics In Vivo.(Research Article)

Leong, Hon S. ; Lizardo, Michael M. ; Ablack, Amber ; Mcpherson, Victor A. ; Wandless, Thomas J. ; Chambers, Ann F. ; Lewis, John D.

PLoS ONE, Jan 19, 2012, Vol.7(1), p.e30177 [Periódico revisado por pares]

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AIB1 Cooperates with ER[alpha] to Promote Epithelial Mesenchymal Transition in Breast Cancer through SNAI1 Activation.(Research Article)

Wang, Miao ; Zhao, Feng ; Li, Shujing ; Chang, Alan K. ; Jia, Zhaojun ; Chen, Yixuan ; Xu, Feihong ; Pan, Hongming ; Wu, Huijian

PLoS ONE, June 7, 2013, Vol.8(6), p.e65556 [Periódico revisado por pares]

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Modulation of the colon cancer cell phenotype by pro-inflammatory macrophages: A preclinical model of surgery-associated inflammation and tumor recurrence

Marcuello, María ; Mayol Girbau, Xavier ; Felipe - Fumero, Eloísa ; Costa, Jaume ; López - Hierro, Laia ; Salvans Ruiz, Silvia ; Alonso Gonçalves, Sandra ; Pascual Damieta, Marta ; Grande Posa, Luís ; Pera Roman, Miguel ; Peritoneal Infection After Colorectal Cancer Surgery Is Associated With A Higher Rate Of Tumor Relapse. We Have Recently Proposed That Soluble Inflammatory Factors Released In Response To A Postoperative Infection Enhance Tumor Progression Features In Residual Tumor Cells. In An Effort To Set Up Models To Study The Mechanisms Of Residual Tumor Cell Activation During Surgery - Associated Inflammation, We Have Analyzed The Phenotypic Response Of Colon Cancer Cell Lines To The Paracrine Effects Of Thp - 1 And U937 Differentiated Human Macrophages, Which Release An Inflammatory Medium Characteristic Of An Innate Immune Response. The Exposure Of The Colon Cancer Cell Lines Ht - 29 And Sw620 To Conditioned Media Isolated From Differentiated Thp - 1 And U937 Macrophages Induced A Mesenchymal - Like Phenotypic Shift, Involving The Activation Of In Vitro Invasiveness. The Inflammatory Media Activated The Β - Catenin/Tcf4 Transcriptional Pathway And Induced The Expression Of Several Mesenchymal (E. G. , Fn1 And Vim) And Tcf4 Target Genes (E. G. , Mmp7, Ptgs2, Met, And Ccd1). Similarly, Differential Expression Of Some Transcription Factors Involved In Epithelial - To - Mesenchymal Transitions (I. E. Zeb1, Snai1, And Snai2) Was Variably Observed In The Colon Cancer Cell Lines When Exposed To The Inflammatory Media. Thp - 1 And U937 Macrophages, Which Displayed Characteristics Of M1 Differentiation, Overexpressed Some Cytokines Previously Shown To Be Induced In Colorectal Cancer Patients With Increased Rates Of Tumor Recurrence Associated With Postoperative Peritoneal Infections, Thus Suggesting Their Pro - Tumoral Character. Therefore, The Environment Created By Inflammatory M1 Macrophages Enhances Features Of Epithelial - To - Mesenchymal Transition, And May Be Useful As A Model To Characterize Pro - Inflammatory Cytokines As Putative Biomarkers Of Tumor Recurrence Risk.

2018

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The Antihelmintic Drug Pyrvinium Pamoate Targets Aggressive Breast Cancer.(Research Article)

Xu, Wei ; Lacerda, Lara ; Debeb, Bisrat G. ; Atkinson, Rachel L. ; Solley, Travis N. ; Li, Li ; Orton, Darren ; Mcmurray, John S. ; Hang, Brian I. ; Lee, Ethan ; Klopp, Ann H. ; Ueno, Naoto T. ; Reuben, James M. ; Krishnamurthy, Savitri ; Woodward, Wendy A.

PLoS ONE, August 27, 2013, Vol.8(8), p.e71508 [Periódico revisado por pares]

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Modeling of Cancer Stem Cell State Transitions Predicts Therapeutic Response.(Report)

Sehl, Mary E. ; Shimada, Miki ; Landeros, Alfonso ; Lange, Kenneth ; Wicha, Max S.

PLoS ONE, Sept 23, 2015, Vol.10(9) [Periódico revisado por pares]

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