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Violacein-Induced chaperone system collapse underlies multistage antiplasmodial activity
Violacein-Induced chaperone system collapse underlies multistage antiplasmodial activity
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Violacein-Induced chaperone system collapse underlies multistage antiplasmodial activity

Tatyana Almeida Tavella Noeli Soares Melo da Silva; Natalie Spillman; Ana Carolina Andrade Vitor Kayano; Gustavo Capatti Cassiano; Adrielle Ayumi Vasconcelos; Antônio Pedro Camargo; Djane Clarys Baia da Silva; Diana Fontinha; Luis Carlos Salazar Alvarez; Letícia Tiburcio Ferreira; Kaira Cristina Peralis Tomaz; Bruno Junior Neves; Ludimila Dias Almeida; Daniel Youssef Bargieri; Marcus Vinicius Guimarães de Lacerda; Pedro Vitor Lemos Cravo; Per Sunnerhagen; Miguel Prudencio; Carolina Horta Andrade; Stefanie Costa Pinto Lopes; Marcelo Falsarella Carazzolle; Leann Tilley; Elizabeth Bilsland; Julio Cesar Borges; Fabio Trindade Maranhão Costa

ACS Infectious Diseases Washington: American Chemical Society v. 7, n. 4, p. 759–776, 2021

Washington American Chemical Society 2021

Localização: IQSC - Inst. Química de São Carlos    (P19310 )(Acessar)

2
The Plasmodium falciparum Artemisinin Susceptibility-Associated AP-2 Adaptin μ Subunit is Clathrin Independent and Essential for Schizont Maturation
The Plasmodium falciparum Artemisinin Susceptibility-Associated AP-2 Adaptin μ Subunit is Clathrin Independent and Essential for Schizont Maturation
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The Plasmodium falciparum Artemisinin Susceptibility-Associated AP-2 Adaptin μ Subunit is Clathrin Independent and Essential for Schizont Maturation

Henrici, Ryan C ; Edwards, Rachel L ; Zoltner, Martin ; van Schalkwyk, Donelly A ; Hart, Melissa N ; Mohring, Franziska ; Moon, Robert W ; Nofal, Stephanie D ; Patel, Avnish ; Flueck, Christian ; Baker, David A ; Odom John, Audrey R ; Field, Mark C ; Sutherland, Colin J Wellems, Thomas E. ; Tilley, Leann

mBio, 2020-02, Vol.11 (1) [Periódico revisado por pares]

United States: American Society for Microbiology

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3
Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome
Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome
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Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome

Bridgford, Jessica L ; Xie, Stanley C ; Cobbold, Simon A ; Pasaje, Charisse Flerida A ; Herrmann, Susann ; Yang, Tuo ; Gillett, David L ; Dick, Lawrence R ; Ralph, Stuart A ; Dogovski, Con ; Spillman, Natalie J ; Tilley, Leann

Nature communications, 2018-09, Vol.9 (1), p.3801-9, Article 3801 [Periódico revisado por pares]

England: Nature Publishing Group

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4
Targeting the cell stress response of Plasmodium falciparum to overcome artemisinin resistance
Targeting the cell stress response of Plasmodium falciparum to overcome artemisinin resistance
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Targeting the cell stress response of Plasmodium falciparum to overcome artemisinin resistance

Dogovski, Con ; Xie, Stanley C ; Burgio, Gaetan ; Bridgford, Jess ; Mok, Sachel ; McCaw, James M ; Chotivanich, Kesinee ; Kenny, Shannon ; Gnädig, Nina ; Straimer, Judith ; Bozdech, Zbynek ; Fidock, David A ; Simpson, Julie A ; Dondorp, Arjen M ; Foote, Simon ; Klonis, Nectarios ; Tilley, Leann Schneider, David S.

PLoS Biology, 2015-04, Vol.13 (4), p.e1002132 [Periódico revisado por pares]

United States: Public Library of Science

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5
An exported protein-interacting complex involved in the trafficking of virulence determinants in Plasmodium-infected erythrocytes
An exported protein-interacting complex involved in the trafficking of virulence determinants in Plasmodium-infected erythrocytes
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An exported protein-interacting complex involved in the trafficking of virulence determinants in Plasmodium-infected erythrocytes

Batinovic, Steven ; McHugh, Emma ; Chisholm, Scott A ; Matthews, Kathryn ; Liu, Boiyin ; Dumont, Laure ; Charnaud, Sarah C ; Schneider, Molly Parkyn ; Gilson, Paul R ; de Koning-Ward, Tania F ; Dixon, Matthew W A ; Tilley, Leann

Nature communications, 2017-07, Vol.8 (1), p.16044-16044, Article 16044 [Periódico revisado por pares]

England: Nature Publishing Group

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6
The exported chaperone Hsp70-x supports virulence functions for Plasmodium falciparum blood stage parasites
The exported chaperone Hsp70-x supports virulence functions for Plasmodium falciparum blood stage parasites
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The exported chaperone Hsp70-x supports virulence functions for Plasmodium falciparum blood stage parasites

Charnaud, Sarah C ; Dixon, Matthew W A ; Nie, Catherine Q ; Chappell, Lia ; Sanders, Paul R ; Nebl, Thomas ; Hanssen, Eric ; Berriman, Matthew ; Chan, Jo-Anne ; Blanch, Adam J ; Beeson, James G ; Rayner, Julian C ; Przyborski, Jude M ; Tilley, Leann ; Crabb, Brendan S ; Gilson, Paul R Spielmann, Tobias

PloS one, 2017-07, Vol.12 (7), p.e0181656-e0181656 [Periódico revisado por pares]

United States: Public Library of Science

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7
Structure- and function-based design of Plasmodium-selective proteasome inhibitors
Structure- and function-based design of Plasmodium-selective proteasome inhibitors
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Structure- and function-based design of Plasmodium-selective proteasome inhibitors

Li, Hao ; O'Donoghue, Anthony J ; van der Linden, Wouter A ; Xie, Stanley C ; Yoo, Euna ; Foe, Ian T ; Tilley, Leann ; Craik, Charles S ; da Fonseca, Paula C A ; Bogyo, Matthew

Nature (London), 2016-02, Vol.530 (7589), p.233-236 [Periódico revisado por pares]

England: Nature Publishing Group

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8
Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy
Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy
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Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy

Xie, Stanley C ; Metcalfe, Riley D ; Dunn, Elyse ; Morton, Craig J ; Huang, Shih-Chung ; Puhalovich, Tanya ; Du, Yawei ; Wittlin, Sergio ; Nie, Shuai ; Luth, Madeline R ; Ma, Liting ; Kim, Mi-Sook ; Pasaje, Charisse Flerida A ; Kumpornsin, Krittikorn ; Giannangelo, Carlo ; Houghton, Fiona J ; Churchyard, Alisje ; Famodimu, Mufuliat T ; Barry, Daniel C ; Gillett, David L ; Dey, Sumanta ; Kosasih, Clara C ; Newman, William ; Niles, Jacquin C ; Lee, Marcus C S ; Baum, Jake ; Ottilie, Sabine ; Winzeler, Elizabeth A ; Creek, Darren J ; Williamson, Nicholas ; Parker, Michael W ; Brand, Stephen ; Langston, Steven P ; Dick, Lawrence R ; Griffin, Michael D W ; Gould, Alexandra E ; Tilley, Leann

Science (American Association for the Advancement of Science), 2022-06, Vol.376 (6597), p.1074-1079 [Periódico revisado por pares]

United States: The American Association for the Advancement of Science

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9
Comparison of the Exposure Time Dependence of the Activities of Synthetic Ozonide Antimalarials and Dihydroartemisinin against K13 Wild-Type and Mutant Plasmodium falciparum Strains
Comparison of the Exposure Time Dependence of the Activities of Synthetic Ozonide Antimalarials and Dihydroartemisinin against K13 Wild-Type and Mutant Plasmodium falciparum Strains
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Comparison of the Exposure Time Dependence of the Activities of Synthetic Ozonide Antimalarials and Dihydroartemisinin against K13 Wild-Type and Mutant Plasmodium falciparum Strains

Yang, Tuo ; Xie, Stanley C ; Cao, Pengxing ; Giannangelo, Carlo ; McCaw, James ; Creek, Darren J ; Charman, Susan A ; Klonis, Nectarios ; Tilley, Leann

Antimicrobial agents and chemotherapy, 2016-08, Vol.60 (8), p.4501-4510 [Periódico revisado por pares]

United States: American Society for Microbiology

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10
Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome
Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome
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Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome

Xie, Stanley C ; Metcalfe, Riley D ; Mizutani, Hirotake ; Puhalovich, Tanya ; Hanssen, Eric ; Morton, Craig J ; Du, Yawei ; Dogovski, Con ; Huang, Shih-Chung ; Ciavarri, Jeffrey ; Hales, Paul ; Griffin, Robert J ; Cohen, Lawrence H ; Chuang, Bei-Ching ; Wittlin, Sergio ; Deni, Ioanna ; Yeo, Tomas ; Ward, Kurt E ; Barry, Daniel C ; Liu, Boyin ; Gillett, David L ; Crespo-Fernandez, Benigno F ; Ottilie, Sabine ; Mittal, Nimisha ; Churchyard, Alisje ; Ferguson, Daniel ; Aguiar, Anna Caroline C ; Guido, Rafael V C ; Baum, Jake ; Hanson, Kirsten K ; Winzeler, Elizabeth A ; Gamo, Francisco-Javier ; Fidock, David A ; Baud, Delphine ; Parker, Michael W ; Brand, Stephen ; Dick, Lawrence R ; Griffin, Michael D W ; Gould, Alexandra E ; Tilley, Leann

Proceedings of the National Academy of Sciences - PNAS, 2021-09, Vol.118 (39), p.1 [Periódico revisado por pares]

United States: National Academy of Sciences

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Deste Autor:

  1. Neves, B
  2. Tomaz, K
  3. Cravo, P
  4. Borges, J
  5. Silva, D

Neste Assunto:

  1. Plasmodium Falciparum
  2. Plasmodium Falciparum
  3. Science & Technology
  4. Malaria
  5. Animals

  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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