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1 |
Material Type: Artigo
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Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson's diseaseTóth, Gergely ; Gardai, Shyra J ; Zago, Wagner ; Bertoncini, Carlos W ; Cremades, Nunilo ; Roy, Susan L ; Tambe, Mitali A ; Rochet, Jean-Christophe ; Galvagnion, Celine ; Skibinski, Gaia ; Finkbeiner, Steven ; Bova, Michael ; Regnstrom, Karin ; Chiou, San-San ; Johnston, Jennifer ; Callaway, Kari ; Anderson, John P ; Jobling, Michael F ; Buell, Alexander K ; Yednock, Ted A ; Knowles, Tuomas P J ; Vendruscolo, Michele ; Christodoulou, John ; Dobson, Christopher M ; Schenk, Dale ; McConlogue, Lisa Cookson, Mark R.PloS one, 2014-02, Vol.9 (2), p.e87133-e87133 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
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2 |
Material Type: Artigo
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Tau enhances α-synuclein aggregation and toxicity in cellular models of synucleinopathyBadiola, Nahuai ; de Oliveira, Rita Machado ; Herrera, Federico ; Guardia-Laguarta, Cristina ; Gonçalves, Susana A ; Pera, Marta ; Suárez-Calvet, Marc ; Clarimon, Jordi ; Outeiro, Tiago Fleming ; Lleó, Alberto Iijima, Koichi M.PloS one, 2011-10, Vol.6 (10), p.e26609 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
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3 |
Material Type: Artigo
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Aggregated Alpha-Synuclein Transfer Efficiently between Cultured Human Neuron-Like Cells and Localize to LysosomesDomert, Jakob ; Sackmann, Christopher ; Severinsson, Emelie ; Agholme, Lotta ; Bergström, Joakim ; Ingelsson, Martin ; Hallbeck, Martin Witt, Stephan N.PloS one, 2016-12, Vol.11 (12), p.e0168700-e0168700 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
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4 |
Material Type: Artigo
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Exosomal cell-to-cell transmission of alpha synuclein oligomersDanzer, Karin M ; Kranich, Lisa R ; Ruf, Wolfgang P ; Cagsal-Getkin, Ozge ; Winslow, Ashley R ; Zhu, Liya ; Vanderburg, Charles R ; McLean, Pamela JMolecular neurodegeneration, 2012-08, Vol.7 (1), p.42-42, Article 42 [Periódico revisado por pares]England: BioMed Central LtdTexto completo disponível |
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Material Type: Artigo
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Ubiquitination increases parkin activity to promote autophagic α-synuclein clearanceLonskaya, Irina ; Desforges, Nicole M ; Hebron, Michaeline L ; Moussa, Charbel E-H Lim, Kah-LeongPloS one, 2013-12, Vol.8 (12), p.e83914 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
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Material Type: Artigo
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α-Synuclein Pathology and Reduced Neurogenesis in the Olfactory System Affect Olfaction in a Mouse Model of Parkinson's DiseaseMartin-Lopez, Eduardo ; Vidyadhara, D J ; Liberia, Teresa ; Meller, Sarah J ; Harmon, Leah E ; Hsu, Ryan M ; Spence, Natalie ; Brennan, Bowen ; Han, Kimberly ; Yücel, Betül ; Chandra, Sreeganga S ; Greer, Charles AThe Journal of neuroscience, 2023-02, Vol.43 (6), p.1051-1071 [Periódico revisado por pares]United States: Society for NeuroscienceTexto completo disponível |
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7 |
Material Type: Artigo
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Dopamine-mediated oxidation of methionine 127 in α-synuclein causes cytotoxicity and oligomerization of α-synucleinNakaso, Kazuhiro ; Tajima, Naoko ; Ito, Satoru ; Teraoka, Mari ; Yamashita, Atsushi ; Horikoshi, Yosuke ; Kikuchi, Daisuke ; Mochida, Shinsuke ; Nakashima, Kenji ; Matsura, Tatsuya Smith, WanliPloS one, 2013-02, Vol.8 (2), p.e55068 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
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8 |
Material Type: Artigo
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Site-specific perturbations of alpha-synuclein fibril structure by the Parkinson's disease associated mutations A53T and E46KLemkau, Luisel R ; Comellas, Gemma ; Lee, Shin W ; Rikardsen, Lars K ; Woods, Wendy S ; George, Julia M ; Rienstra, Chad M Greggio, ElisaPloS one, 2013-03, Vol.8 (3), p.e49750-e49750 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
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9 |
Material Type: Artigo
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Genetics in Parkinson disease: Mendelian versus non‐Mendelian inheritanceHernandez, Dena G. ; Reed, Xylena ; Singleton, Andrew B.Journal of neurochemistry, 2016-10, Vol.139 (S1), p.59-74 [Periódico revisado por pares]England: Blackwell Publishing LtdTexto completo disponível |
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10 |
Material Type: Artigo
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Loss of β-glucocerebrosidase activity does not affect alpha-synuclein levels or lysosomal function in neuronal cellsDermentzaki, Georgia ; Dimitriou, Evangelia ; Xilouri, Maria ; Michelakakis, Helen ; Stefanis, Leonidas Lewis, PatrickPloS one, 2013-04, Vol.8 (4), p.e60674-e60674 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |