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Refinado por: Nome da Publicação: PLoS One remover assunto: Multidisciplinary Sciences remover
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Alpha-synuclein induces lysosomal rupture and cathepsin dependent reactive oxygen species following endocytosis
Alpha-synuclein induces lysosomal rupture and cathepsin dependent reactive oxygen species following endocytosis
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Alpha-synuclein induces lysosomal rupture and cathepsin dependent reactive oxygen species following endocytosis

Freeman, David ; Cedillos, Rudy ; Choyke, Samantha ; Lukic, Zana ; McGuire, Kathleen ; Marvin, Shauna ; Burrage, Andrew M ; Sudholt, Stacey ; Rana, Ajay ; O'Connor, Christopher ; Wiethoff, Christopher M ; Campbell, Edward M Kahle, Philipp J.

PloS one, 2013-04, Vol.8 (4), p.e62143-e62143 [Periódico revisado por pares]

United States: Public Library of Science

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2
Bacterial Chaperones CsgE and CsgC Differentially Modulate Human α-Synuclein Amyloid Formation via Transient Contacts
Bacterial Chaperones CsgE and CsgC Differentially Modulate Human α-Synuclein Amyloid Formation via Transient Contacts
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Bacterial Chaperones CsgE and CsgC Differentially Modulate Human α-Synuclein Amyloid Formation via Transient Contacts

Chorell, Erik ; Andersson, Emma ; Evans, Margery L ; Jain, Neha ; Götheson, Anna ; Åden, Jörgen ; Chapman, Matthew R ; Almqvist, Fredrik ; Wittung-Stafshede, Pernilla Baskakov, Ilia V

PloS one, 2015, Vol.10 (10), p.e0140194-e0140194 [Periódico revisado por pares]

United States: Public Library of Science

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3
SNCA triplication Parkinson's patient's iPSC-derived DA neurons accumulate α-synuclein and are susceptible to oxidative stress
SNCA triplication Parkinson's patient's iPSC-derived DA neurons accumulate α-synuclein and are susceptible to oxidative stress
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SNCA triplication Parkinson's patient's iPSC-derived DA neurons accumulate α-synuclein and are susceptible to oxidative stress

Byers, Blake ; Cord, Branden ; Nguyen, Ha Nam ; Schüle, Birgitt ; Fenno, Lief ; Lee, Patrick C ; Deisseroth, Karl ; Langston, J William ; Pera, Renee Reijo ; Palmer, Theo D Chin, Wei-Chun

PloS one, 2011-11, Vol.6 (11), p.e26159-e26159 [Periódico revisado por pares]

United States: Public Library of Science

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4
Preclinical development of a vaccine against oligomeric alpha-synuclein based on virus-like particles
Preclinical development of a vaccine against oligomeric alpha-synuclein based on virus-like particles
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Preclinical development of a vaccine against oligomeric alpha-synuclein based on virus-like particles

Doucet, Marika ; El-Turabi, Aadil ; Zabel, Franziska ; Hunn, Benjamin H M ; Bengoa-Vergniory, Nora ; Cioroch, Milena ; Ramm, Mauricio ; Smith, Amy M ; Gomes, Ariane Cruz ; Cabral de Miranda, Gustavo ; Wade-Martins, Richard ; Bachmann, Martin F Kahle, Philipp J.

PloS one, 2017-08, Vol.12 (8), p.e0181844 [Periódico revisado por pares]

United States: Public Library of Science

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5
Abberant alpha-synuclein confers toxicity to neurons in part through inhibition of chaperone-mediated autophagy
Abberant alpha-synuclein confers toxicity to neurons in part through inhibition of chaperone-mediated autophagy
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Abberant alpha-synuclein confers toxicity to neurons in part through inhibition of chaperone-mediated autophagy

Xilouri, Maria ; Vogiatzi, Tereza ; Vekrellis, Kostas ; Park, David ; Stefanis, Leonidas Gendelman, Howard E.

PloS one, 2009-05, Vol.4 (5), p.e5515 [Periódico revisado por pares]

United States: Public Library of Science

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6
Formation of toxic oligomeric alpha-synuclein species in living cells
Formation of toxic oligomeric alpha-synuclein species in living cells
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Formation of toxic oligomeric alpha-synuclein species in living cells

Outeiro, Tiago Fleming ; Putcha, Preeti ; Tetzlaff, Julie E ; Spoelgen, Robert ; Koker, Mirjam ; Carvalho, Filipe ; Hyman, Bradley T ; McLean, Pamela J Koutsopoulos, Sotirios

PloS one, 2008-04, Vol.3 (4), p.e1867 [Periódico revisado por pares]

United States: Public Library of Science

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7
Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson's disease
Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson's disease
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Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson's disease

Tóth, Gergely ; Gardai, Shyra J ; Zago, Wagner ; Bertoncini, Carlos W ; Cremades, Nunilo ; Roy, Susan L ; Tambe, Mitali A ; Rochet, Jean-Christophe ; Galvagnion, Celine ; Skibinski, Gaia ; Finkbeiner, Steven ; Bova, Michael ; Regnstrom, Karin ; Chiou, San-San ; Johnston, Jennifer ; Callaway, Kari ; Anderson, John P ; Jobling, Michael F ; Buell, Alexander K ; Yednock, Ted A ; Knowles, Tuomas P J ; Vendruscolo, Michele ; Christodoulou, John ; Dobson, Christopher M ; Schenk, Dale ; McConlogue, Lisa Cookson, Mark R.

PloS one, 2014-02, Vol.9 (2), p.e87133-e87133 [Periódico revisado por pares]

United States: Public Library of Science

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8
A novel panel of α-synuclein antibodies reveal distinctive staining profiles in synucleinopathies
A novel panel of α-synuclein antibodies reveal distinctive staining profiles in synucleinopathies
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A novel panel of α-synuclein antibodies reveal distinctive staining profiles in synucleinopathies

Dhillon, Jess-Karan S ; Riffe, Cara ; Moore, Brenda D ; Ran, Yong ; Chakrabarty, Paramita ; Golde, Todd E ; Giasson, Benoit I Witt, Stephan N.

PloS one, 2017-09, Vol.12 (9), p.e0184731-e0184731 [Periódico revisado por pares]

United States: Public Library of Science

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9
Bifunctional Anti-Non-Amyloid Component α-Synuclein Nanobodies Are Protective In Situ
Bifunctional Anti-Non-Amyloid Component α-Synuclein Nanobodies Are Protective In Situ
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Bifunctional Anti-Non-Amyloid Component α-Synuclein Nanobodies Are Protective In Situ

Butler, David C ; Joshi, Shubhada N ; Genst, Erwin De ; Baghel, Ankit S ; Dobson, Christopher M ; Messer, Anne Witt, Stephan N.

PloS one, 2016-11, Vol.11 (11), p.e0165964-e0165964 [Periódico revisado por pares]

United States: Public Library of Science

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10
Fractalkine Signaling Regulates the Inflammatory Response in an α-Synuclein Model of Parkinson Disease
Fractalkine Signaling Regulates the Inflammatory Response in an α-Synuclein Model of Parkinson Disease
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Fractalkine Signaling Regulates the Inflammatory Response in an α-Synuclein Model of Parkinson Disease

Thome, Aaron D ; Standaert, David G ; Harms, Ashley S Tansey, Malú G.

PloS one, 2015-10, Vol.10 (10), p.e0140566 [Periódico revisado por pares]

United States: Public Library of Science

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