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Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS
Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS
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Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS

Chouchani, Edward T ; Pell, Victoria R ; Gaude, Edoardo ; Aksentijević, Dunja ; Sundier, Stephanie Y ; Robb, Ellen L ; Logan, Angela ; Nadtochiy, Sergiy M ; Ord, Emily N J ; Smith, Anthony C ; Eyassu, Filmon ; Shirley, Rachel ; Hu, Chou-Hui ; Dare, Anna J ; James, Andrew M ; Rogatti, Sebastian ; Hartley, Richard C ; Eaton, Simon ; Costa, Ana S H ; Brookes, Paul S ; Davidson, Sean M ; Duchen, Michael R ; Saeb-Parsy, Kourosh ; Shattock, Michael J ; Robinson, Alan J ; Work, Lorraine M ; Frezza, Christian ; Krieg, Thomas ; Murphy, Michael P

Nature (London), 2014-11, Vol.515 (7527), p.431-435 [Periódico revisado por pares]

England: Nature Publishing Group

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2
Rac2 Modulates Atherosclerotic Calcification by Regulating Macrophage Interleukin-1β Production
Rac2 Modulates Atherosclerotic Calcification by Regulating Macrophage Interleukin-1β Production
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Rac2 Modulates Atherosclerotic Calcification by Regulating Macrophage Interleukin-1β Production

Ceneri, Nicolle ; Zhao, Lina ; Young, Bryan D ; Healy, Abigail ; Coskun, Suleyman ; Vasavada, Hema ; Yarovinsky, Timur O ; Ike, Kenneth ; Pardi, Ruggero ; Qin, Lingfen ; Qin, Li ; Tellides, George ; Hirschi, Karen ; Meadows, Judith ; Soufer, Robert ; Chun, Hyung J ; Sadeghi, Mehran ; Bender, Jeffrey R ; Morrison, Alan R

Arteriosclerosis, thrombosis, and vascular biology, 2017-02, Vol.37 (2), p.328-340 [Periódico revisado por pares]

United States: American Heart Association, Inc

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3
Extracellular caspase-6 drives murine inflammatory pain via microglial TNF-α secretion
Extracellular caspase-6 drives murine inflammatory pain via microglial TNF-α secretion
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Extracellular caspase-6 drives murine inflammatory pain via microglial TNF-α secretion

Berta, Temugin ; Park, Chul-Kyu ; Xu, Zhen-Zhong ; Xie, Ruo-Gang ; Liu, Tong ; Lü, Ning ; Liu, Yen-Chin ; Ji, Ru-Rong

The Journal of clinical investigation, 2014-03, Vol.124 (3), p.1173-1186 [Periódico revisado por pares]

United States: American Society for Clinical Investigation

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4
A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease
A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease
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A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease

Mass, Elvira ; Jacome-Galarza, Christian E ; Blank, Thomas ; Lazarov, Tomi ; Durham, Benjamin H ; Ozkaya, Neval ; Pastore, Alessandro ; Schwabenland, Marius ; Chung, Young Rock ; Rosenblum, Marc K ; Prinz, Marco ; Abdel-Wahab, Omar ; Geissmann, Frederic

Nature (London), 2017-09, Vol.549 (7672), p.389-393 [Periódico revisado por pares]

England: Nature Publishing Group

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5
AMP-Activated Protein Kinase Activation in Dorsal Root Ganglion Suppresses mTOR/p70S6K Signaling and Alleviates Painful Radiculopathies in Lumbar Disc Herniation Rat Model
AMP-Activated Protein Kinase Activation in Dorsal Root Ganglion Suppresses mTOR/p70S6K Signaling and Alleviates Painful Radiculopathies in Lumbar Disc Herniation Rat Model
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AMP-Activated Protein Kinase Activation in Dorsal Root Ganglion Suppresses mTOR/p70S6K Signaling and Alleviates Painful Radiculopathies in Lumbar Disc Herniation Rat Model

Liu, Yuantong ; Li, Jianmin ; Li, Hao ; Shang, Yue ; Guo, Yan ; Li, Zhenzhong ; Liu, Zhen

Spine (Philadelphia, Pa. 1976), 2019-08, Vol.44 (15), p.E865-E872 [Periódico revisado por pares]

United States: Copyright Wolters Kluwer Health, Inc. All rights reserved

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6
Mutations in KAT6B, Encoding a Histone Acetyltransferase, Cause Genitopatellar Syndrome
Mutations in KAT6B, Encoding a Histone Acetyltransferase, Cause Genitopatellar Syndrome
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Mutations in KAT6B, Encoding a Histone Acetyltransferase, Cause Genitopatellar Syndrome

Campeau, Philippe M. ; Kim, Jaeseung C. ; Lu, James T. ; Schwartzentruber, Jeremy A. ; Abdul-Rahman, Omar A. ; Schlaubitz, Silke ; Murdock, David M. ; Jiang, Ming-Ming ; Lammer, Edward J. ; Enns, Gregory M. ; Rhead, William J. ; Rowland, Jon ; Robertson, Stephen P. ; Cormier-Daire, Valérie ; Bainbridge, Matthew N. ; Yang, Xiang-Jiao ; Gingras, Marie-Claude ; Gibbs, Richard A. ; Rosenblatt, David S. ; Majewski, Jacek ; Lee, Brendan H.

American journal of human genetics, 2012-02, Vol.90 (2), p.282-289 [Periódico revisado por pares]

Cambridge, MA: Elsevier Inc

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7
Characterization of Brain Neurons That Express Enzymes Mediating Neurosteroid Biosynthesis
Characterization of Brain Neurons That Express Enzymes Mediating Neurosteroid Biosynthesis
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Characterization of Brain Neurons That Express Enzymes Mediating Neurosteroid Biosynthesis

Agís-Balboa, Roberto C. ; Pinna, Graziano ; Zhubi, Adrian ; Maloku, Ekrem ; Veldic, Marin ; Costa, Erminio ; Guidotti, Alessandro

Proceedings of the National Academy of Sciences - PNAS, 2006-09, Vol.103 (39), p.14602-14607 [Periódico revisado por pares]

United States: National Academy of Sciences

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8
Upregulation of neuronal kynurenine 3-monooxygenase mediates depression-like behavior in a mouse model of neuropathic pain
Upregulation of neuronal kynurenine 3-monooxygenase mediates depression-like behavior in a mouse model of neuropathic pain
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Upregulation of neuronal kynurenine 3-monooxygenase mediates depression-like behavior in a mouse model of neuropathic pain

Laumet, Geoffroy ; Zhou, Wenjun ; Dantzer, Robert ; Edralin, Jules D. ; Huo, XiaoJiao ; Budac, David P. ; O'Connor, Jason C. ; Lee, Anna W. ; Heijnen, Cobi J. ; Kavelaars, Annemieke

Brain, behavior, and immunity, 2017-11, Vol.66, p.94-102 [Periódico revisado por pares]

Netherlands: Elsevier Inc

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9
Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity
Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity
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Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity

Kraus, Daniel ; Yang, Qin ; Kong, Dong ; Banks, Alexander S ; Zhang, Lin ; Rodgers, Joseph T ; Pirinen, Eija ; Pulinilkunnil, Thomas C ; Gong, Fengying ; Wang, Ya-chin ; Cen, Yana ; Sauve, Anthony A ; Asara, John M ; Peroni, Odile D ; Monia, Brett P ; Bhanot, Sanjay ; Alhonen, Leena ; Puigserver, Pere ; Kahn, Barbara B

Nature (London), 2014-04, Vol.508 (7495), p.258-262 [Periódico revisado por pares]

England: Nature Publishing Group

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10
Matrix Metalloproteinase-28 Deletion Exacerbates Cardiac Dysfunction and Rupture After Myocardial Infarction in Mice by Inhibiting M2 Macrophage Activation
Matrix Metalloproteinase-28 Deletion Exacerbates Cardiac Dysfunction and Rupture After Myocardial Infarction in Mice by Inhibiting M2 Macrophage Activation
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Matrix Metalloproteinase-28 Deletion Exacerbates Cardiac Dysfunction and Rupture After Myocardial Infarction in Mice by Inhibiting M2 Macrophage Activation

Ma, Yonggang ; Halade, Ganesh V ; Zhang, Jianhua ; Ramirez, Trevi A ; Levin, Daniel ; Voorhees, Andrew ; Jin, Yu-Fang ; Han, Hai-Chao ; Manicone, Anne M ; Lindsey, Merry L

Circulation research, 2013-02, Vol.112 (4), p.675-688 [Periódico revisado por pares]

United States: American Heart Association, Inc

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