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The amino acid sensor GCN2 controls gut inflammation by inhibiting inflammasome activation
The amino acid sensor GCN2 controls gut inflammation by inhibiting inflammasome activation
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The amino acid sensor GCN2 controls gut inflammation by inhibiting inflammasome activation

Ravindran, Rajesh ; Loebbermann, Jens ; Nakaya, Helder I ; Khan, Nooruddin ; Ma, Hualing ; Gama, Leonardo ; Machiah, Deepa K ; Lawson, Benton ; Hakimpour, Paul ; Wang, Yi-Chong ; Li, Shuzhao ; Sharma, Prachi ; Kaufman, Randal J ; Martinez, Jennifer ; Pulendran, Bali

Nature (London), 2016-03, Vol.531 (7595), p.523-527 [Periódico revisado por pares]

England: Nature Publishing Group

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2
Mitochondrial stress is relayed to the cytosol by an OMA1-DELE1-HRI pathway
Mitochondrial stress is relayed to the cytosol by an OMA1-DELE1-HRI pathway
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Mitochondrial stress is relayed to the cytosol by an OMA1-DELE1-HRI pathway

Guo, Xiaoyan ; Aviles, Giovanni ; Liu, Yi ; Tian, Ruilin ; Unger, Bret A ; Lin, Yu-Hsiu T ; Wiita, Arun P ; Xu, Ke ; Correia, M Almira ; Kampmann, Martin

Nature (London), 2020-03, Vol.579 (7799), p.427-432 [Periódico revisado por pares]

England: Nature Publishing Group

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3
AMPK: guardian of metabolism and mitochondrial homeostasis
AMPK: guardian of metabolism and mitochondrial homeostasis
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AMPK: guardian of metabolism and mitochondrial homeostasis

Herzig, Sébastien ; Shaw, Reuben J

Nature reviews. Molecular cell biology, 2018-02, Vol.19 (2), p.121-135 [Periódico revisado por pares]

England: Nature Publishing Group

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4
Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy
Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy
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Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy

Huber, Kilian V M ; Salah, Eidarus ; Radic, Branka ; Gridling, Manuela ; Elkins, Jonathan M ; Stukalov, Alexey ; Jemth, Ann-Sofie ; Göktürk, Camilla ; Sanjiv, Kumar ; Strömberg, Kia ; Pham, Therese ; Berglund, Ulrika Warpman ; Colinge, Jacques ; Bennett, Keiryn L ; Loizou, Joanna I ; Helleday, Thomas ; Knapp, Stefan ; Superti-Furga, Giulio

Nature (London), 2014-04, Vol.508 (7495), p.222-227 [Periódico revisado por pares]

England: Nature Publishing Group

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5
Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia
Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia
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Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia

Yankova, Eliza ; Blackaby, Wesley ; Albertella, Mark ; Rak, Justyna ; De Braekeleer, Etienne ; Tsagkogeorga, Georgia ; Pilka, Ewa S ; Aspris, Demetrios ; Leggate, Dan ; Hendrick, Alan G ; Webster, Natalie A ; Andrews, Byron ; Fosbeary, Richard ; Guest, Patrick ; Irigoyen, Nerea ; Eleftheriou, Maria ; Gozdecka, Malgorzata ; Dias, Joao M L ; Bannister, Andrew J ; Vick, Binje ; Jeremias, Irmela ; Vassiliou, George S ; Rausch, Oliver ; Tzelepis, Konstantinos ; Kouzarides, Tony

Nature (London), 2021-05, Vol.593 (7860), p.597-601 [Periódico revisado por pares]

England: Nature Publishing Group

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6
MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool
MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool
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MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

Gad, Helge ; Koolmeister, Tobias ; Jemth, Ann-Sofie ; Eshtad, Saeed ; Jacques, Sylvain A ; Ström, Cecilia E ; Svensson, Linda M ; Schultz, Niklas ; Lundbäck, Thomas ; Einarsdottir, Berglind Osk ; Saleh, Aljona ; Göktürk, Camilla ; Baranczewski, Pawel ; Svensson, Richard ; Berntsson, Ronnie P-A ; Gustafsson, Robert ; Strömberg, Kia ; Sanjiv, Kumar ; Jacques-Cordonnier, Marie-Caroline ; Desroses, Matthieu ; Gustavsson, Anna-Lena ; Olofsson, Roger ; Johansson, Fredrik ; Homan, Evert J ; Loseva, Olga ; Bräutigam, Lars ; Johansson, Lars ; Höglund, Andreas ; Hagenkort, Anna ; Pham, Therese ; Altun, Mikael ; Gaugaz, Fabienne Z ; Vikingsson, Svante ; Evers, Bastiaan ; Henriksson, Martin ; Vallin, Karl S A ; Wallner, Olov A ; Hammarström, Lars G J ; Wiita, Elisee ; Almlöf, Ingrid ; Kalderén, Christina ; Axelsson, Hanna ; Djureinovic, Tatjana ; Puigvert, Jordi Carreras ; Häggblad, Maria ; Jeppsson, Fredrik ; Martens, Ulf ; Lundin, Cecilia ; Lundgren, Bo ; Granelli, Ingrid ; Jensen, Annika Jenmalm ; Artursson, Per ; Nilsson, Jonas A ; Stenmark, Pål ; Scobie, Martin ; Berglund, Ulrika Warpman ; Helleday, Thomas

Nature (London), 2014-04, Vol.508 (7495), p.215-221 [Periódico revisado por pares]

England: Nature Publishing Group

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7
A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol
A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol
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A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol

Fessler, Evelyn ; Eckl, Eva-Maria ; Schmitt, Sabine ; Mancilla, Igor Alves ; Meyer-Bender, Matthias F ; Hanf, Monika ; Philippou-Massier, Julia ; Krebs, Stefan ; Zischka, Hans ; Jae, Lucas T

Nature (London), 2020-03, Vol.579 (7799), p.433-437 [Periódico revisado por pares]

England: Nature Publishing Group

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8
miR394 and LCR are involved in Arabidopsis salt and drought stress responses in an abscisic acid-dependent manner
miR394 and LCR are involved in Arabidopsis salt and drought stress responses in an abscisic acid-dependent manner
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miR394 and LCR are involved in Arabidopsis salt and drought stress responses in an abscisic acid-dependent manner

Song, Jian Bo ; Gao, Shuai ; Sun, Di ; Li, Hua ; Shu, Xia Xia ; Yang, Zhi Min

BMC plant biology, 2013-12, Vol.13 (1), p.210-210, Article 210 [Periódico revisado por pares]

England: BioMed Central Ltd

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9
p53 regulation of ammonia metabolism through urea cycle controls polyamine biosynthesis
p53 regulation of ammonia metabolism through urea cycle controls polyamine biosynthesis
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p53 regulation of ammonia metabolism through urea cycle controls polyamine biosynthesis

Li, Le ; Mao, Youxiang ; Zhao, Lina ; Li, Lijia ; Wu, Jinjun ; Zhao, Mengjia ; Du, Wenjing ; Yu, Li ; Jiang, Peng

Nature (London), 2019-03, Vol.567 (7747), p.253-256 [Periódico revisado por pares]

England: Nature Publishing Group

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10
Serine is a natural ligand and allosteric activator of pyruvate kinase M2
Serine is a natural ligand and allosteric activator of pyruvate kinase M2
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Serine is a natural ligand and allosteric activator of pyruvate kinase M2

CHANETON, Barbara ; HILLMANN, Petra ; FREZZA, Christian ; O'REILLY, Marc ; GOTTLIEB, Eyal ; LIANGZHENG ; MARTIN, Agnès C. L ; MADDOCKS, Oliver D. K ; CHOKKATHUKALAM, Achuthanunni ; COYLE, Joseph E ; JANKEVICS, Andris ; HOLDING, Finn P ; VOUSDEN, Karen H

Nature (London), 2012-11, Vol.491 (7424), p.458-462 [Periódico revisado por pares]

London: Nature Publishing Group

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