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L-Type amino acid transporter 1 as a target for drug delivery
L-Type amino acid transporter 1 as a target for drug delivery
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L-Type amino acid transporter 1 as a target for drug delivery

Puris, Elena ; Gynther, Mikko ; Auriola, Seppo ; Huttunen, Kristiina M.

Pharmaceutical research, 2020-05, Vol.37 (5), p.88-88, Article 88 [Periódico revisado por pares]

New York: Springer US

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L-type amino acid transporter 1 utilizing prodrugs: How to achieve effective brain delivery and low systemic exposure of drugs
L-type amino acid transporter 1 utilizing prodrugs: How to achieve effective brain delivery and low systemic exposure of drugs
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L-type amino acid transporter 1 utilizing prodrugs: How to achieve effective brain delivery and low systemic exposure of drugs

Puris, Elena ; Gynther, Mikko ; Huttunen, Johanna ; Petsalo, Aleksanteri ; Huttunen, Kristiina M.

Journal of controlled release, 2017-09, Vol.261, p.93-104 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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3
Pulse transit time estimation of aortic pulse wave velocity and blood pressure using machine learning and simulated training data
Pulse transit time estimation of aortic pulse wave velocity and blood pressure using machine learning and simulated training data
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Pulse transit time estimation of aortic pulse wave velocity and blood pressure using machine learning and simulated training data

Huttunen, Janne M J ; Kärkkäinen, Leo ; Lindholm, Harri Beard, Daniel A

PLoS computational biology, 2019-08, Vol.15 (8), p.e1007259-e1007259 [Periódico revisado por pares]

United States: Public Library of Science

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4
L-Type amino acid transporter 1 (LAT1)-utilizing prodrugs are carrier-selective despite having low affinity for organic anion transporting polypeptides (OATPs)
L-Type amino acid transporter 1 (LAT1)-utilizing prodrugs are carrier-selective despite having low affinity for organic anion transporting polypeptides (OATPs)
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L-Type amino acid transporter 1 (LAT1)-utilizing prodrugs are carrier-selective despite having low affinity for organic anion transporting polypeptides (OATPs)

Huttunen, Johanna ; Gynther, Mikko ; Vellonen, Kati-Sisko ; Huttunen, Kristiina M.

International journal of pharmaceutics, 2019-11, Vol.571, p.118714, Article 118714 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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5
A Selective and Slowly Reversible Inhibitor of l‑Type Amino Acid Transporter 1 (LAT1) Potentiates Antiproliferative Drug Efficacy in Cancer Cells
A Selective and Slowly Reversible Inhibitor of l‑Type Amino Acid Transporter 1 (LAT1) Potentiates Antiproliferative Drug Efficacy in Cancer Cells
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A Selective and Slowly Reversible Inhibitor of l‑Type Amino Acid Transporter 1 (LAT1) Potentiates Antiproliferative Drug Efficacy in Cancer Cells

Huttunen, Kristiina M ; Gynther, Mikko ; Huttunen, Johanna ; Puris, Elena ; Spicer, Julie A ; Denny, William A

Journal of medicinal chemistry, 2016-06, Vol.59 (12), p.5740-5751 [Periódico revisado por pares]

United States: American Chemical Society

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6
Prodrugs - An Efficient Way to Breach Delivery and Targeting Barriers
Prodrugs - An Efficient Way to Breach Delivery and Targeting Barriers
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Prodrugs - An Efficient Way to Breach Delivery and Targeting Barriers

Huttunen, Kristiina M ; Rautio, Jarkko

Current topics in medicinal chemistry, 2011-09, Vol.11 (18), p.2265-2287 [Periódico revisado por pares]

United Arab Emirates: Bentham Science Publishers Ltd

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7
Comparison of Experimental Strategies to Study l-Type Amino Acid Transporter 1 (LAT1) Utilization by Ligands
Comparison of Experimental Strategies to Study l-Type Amino Acid Transporter 1 (LAT1) Utilization by Ligands
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Comparison of Experimental Strategies to Study l-Type Amino Acid Transporter 1 (LAT1) Utilization by Ligands

Huttunen, Johanna ; Agami, Mahmoud ; Tampio, Janne ; Montaser, Ahmed B ; Huttunen, Kristiina M

Molecules (Basel, Switzerland), 2021-12, Vol.27 (1), p.37 [Periódico revisado por pares]

Switzerland: MDPI AG

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8
Effective Cellular Transport of Ortho -Halogenated Sulfonamide Derivatives of Metformin Is Related to Improved Antiproliferative Activity and Apoptosis Induction in MCF-7 Cells
Effective Cellular Transport of Ortho -Halogenated Sulfonamide Derivatives of Metformin Is Related to Improved Antiproliferative Activity and Apoptosis Induction in MCF-7 Cells
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Effective Cellular Transport of Ortho -Halogenated Sulfonamide Derivatives of Metformin Is Related to Improved Antiproliferative Activity and Apoptosis Induction in MCF-7 Cells

Markowicz-Piasecka, Magdalena ; Komeil, Ibrahim ; Huttunen, Johanna ; Sikora, Joanna ; Huttunen, Kristiina M

International journal of molecular sciences, 2020-03, Vol.21 (7), p.2389 [Periódico revisado por pares]

Switzerland: MDPI AG

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9
The association between subjective maternal stress during pregnancy and offspring clinically diagnosed psychiatric disorders
The association between subjective maternal stress during pregnancy and offspring clinically diagnosed psychiatric disorders
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The association between subjective maternal stress during pregnancy and offspring clinically diagnosed psychiatric disorders

Brannigan, R. ; Cannon, M. ; Tanskanen, A. ; Huttunen, M. O. ; Leacy, F. P. ; Clarke, M. C.

Acta psychiatrica Scandinavica, 2019-04, Vol.139 (4), p.304-310 [Periódico revisado por pares]

United States: Blackwell Publishing Ltd

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10
Structural Comparison of Sulfonamide-Based Derivatives That Can Improve Anti-Coagulation Properties of Metformin
Structural Comparison of Sulfonamide-Based Derivatives That Can Improve Anti-Coagulation Properties of Metformin
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Structural Comparison of Sulfonamide-Based Derivatives That Can Improve Anti-Coagulation Properties of Metformin

Zajda, Agnieszka ; Sikora, Joanna ; Huttunen, Kristiina M ; Markowicz-Piasecka, Magdalena

International journal of molecular sciences, 2022-04, Vol.23 (8), p.4132 [Periódico revisado por pares]

Switzerland: MDPI AG

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