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Material Type: Artigo
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Fast Identification of Possible Drug Treatment of Coronavirus Disease-19 (COVID-19) through Computational Drug Repurposing StudyWang, JunmeiJournal of chemical information and modeling, 2020-06, Vol.60 (6), p.3277-3286 [Periódico revisado por pares]United States: American Chemical SocietyTexto completo disponível |
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Material Type: Artigo
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A two-pronged strategy to suppress host protein synthesis by SARS coronavirus Nsp1 proteinKamitani, Wataru ; Huang, Cheng ; Narayanan, Krishna ; Lokugamage, Kumari G ; Makino, ShinjiNature structural & molecular biology, 2009-11, Vol.16 (11), p.1134-1140 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Anti-HCV and anti-malaria agent, potential candidates to repurpose for coronavirus infection: Virtual screening, molecular docking, and molecular dynamics simulation studyHosseini, Faezeh Sadat ; Amanlou, MassoudLife sciences (1973), 2020-10, Vol.258, p.118205-118205, Article 118205 [Periódico revisado por pares]Netherlands: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Global prevalence of pre-existing HCV variants resistant to direct-acting antiviral agents (DAAs): mining the GenBank HCV genome dataChen, Zhi-Wei ; Li, Hu ; Ren, Hong ; Hu, PengScientific reports, 2016-02, Vol.6 (1), p.20310-20310, Article 20310 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Molecular dynamics and docking reveal the potency of novel GTP derivatives against RNA dependent RNA polymerase of genotype 4a HCVElfiky, Abdo A. ; Ismail, AlaaLife sciences (1973), 2019-12, Vol.238, p.116958-116958, Article 116958 [Periódico revisado por pares]Netherlands: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Drug resistance against HCV NS3/4A inhibitors is defined by the balance of substrate recognition versus inhibitor bindingRomano, Keith P. ; Ali, Akbar ; Royer, William E. ; Schiffer, Celia A. ; Coffin, John M.Proceedings of the National Academy of Sciences - PNAS, 2010-12, Vol.107 (49), p.20986-20991 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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The Role of RASs /RVs in the Current Management of HCVMalandris, Konstantinos ; Kalopitas, Georgios ; Theocharidou, Eleni ; Germanidis, GeorgiosViruses, 2021-10, Vol.13 (10), p.2096 [Periódico revisado por pares]Switzerland: MDPI AGTexto completo disponível |
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Material Type: Artigo
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In Vitro Resistance Profile of the Hepatitis C Virus NS3/4A Protease Inhibitor TMC435LENZ, Oliver ; VERBINNEN, Thierry ; VERMEIREN, Katrien ; IVENS, Tania ; RABOISSON, Pierre ; EDLUND, Michael ; STORM, Susan ; VRANG, Lotta ; DE KOCK, Herman ; FANNING, Gregory C ; SIMMEN, Kenneth A ; LIN, Tse-I ; VIJGEN, Leen ; CUMMINGS, Maxwell D ; LINDBERG, Jimmy ; MARTIN BERKE, Jan ; DEHERTOGH, Pascale ; FRANSEN, Els ; SCHOLLIERS, AnnickAntimicrobial Agents and Chemotherapy, 2010-05, Vol.54 (5), p.1878-1887 [Periódico revisado por pares]Washington, DC: American Society for MicrobiologyTexto completo disponível |
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Material Type: Artigo
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Discovery of MK-8742: An HCV NS5A Inhibitor with Broad Genotype ActivityCoburn, Craig A. ; Meinke, Peter T. ; Chang, Wei ; Fandozzi, Christine M. ; Graham, Donald J. ; Hu, Bin ; Huang, Qian ; Kargman, Stacia ; Kozlowski, Joseph ; Liu, Rong ; McCauley, John A. ; Nomeir, Amin A. ; Soll, Richard M. ; Vacca, Joseph P. ; Wang, Dahai ; Wu, Hao ; Zhong, Bin ; Olsen, David B. ; Ludmerer, Steven W.ChemMedChem, 2013-12, Vol.8 (12), p.1930-1940 [Periódico revisado por pares]Weinheim: WILEY-VCH VerlagTexto completo disponível |
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Material Type: Artigo
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A short hepatitis C virus NS5A peptide expression by AAV vector modulates human T cell activation and reduces vector immunogenicityColon-Moran, Winston ; Baer, Alan ; Lamture, Gauri ; Stapleton, Jack T ; Fischer, Joseph W ; Bhattarai, NirjalGene therapy, 2022-11, Vol.29 (10-11), p.616-623 [Periódico revisado por pares]England: Nature Publishing GroupSem texto completo |