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In Vitro Antiviral Activity and Resistance Profile of the Next-Generation Hepatitis C Virus NS3/4A Protease Inhibitor Glecaprevir
In Vitro Antiviral Activity and Resistance Profile of the Next-Generation Hepatitis C Virus NS3/4A Protease Inhibitor Glecaprevir
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In Vitro Antiviral Activity and Resistance Profile of the Next-Generation Hepatitis C Virus NS3/4A Protease Inhibitor Glecaprevir

Ng, Teresa I ; Tripathi, Rakesh ; Reisch, Thomas ; Lu, Liangjun ; Middleton, Timothy ; Hopkins, Todd A ; Pithawalla, Ron ; Irvin, Michelle ; Dekhtyar, Tatyana ; Krishnan, Preethi ; Schnell, Gretja ; Beyer, Jill ; McDaniel, Keith F ; Ma, Jun ; Wang, Guoqiang ; Jiang, Li-Juan ; Or, Yat Sun ; Kempf, Dale ; Pilot-Matias, Tami ; Collins, Christine

Antimicrobial agents and chemotherapy, 2018-01, Vol.62 (1) [Periódico revisado por pares]

United States: American Society for Microbiology

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2
A Novel Approach to Develop New and Potent Inhibitors for the Simultaneous Inhibition of Protease and Helicase Activities of HCV NS3/4A Protease: A Computational Approach
A Novel Approach to Develop New and Potent Inhibitors for the Simultaneous Inhibition of Protease and Helicase Activities of HCV NS3/4A Protease: A Computational Approach
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A Novel Approach to Develop New and Potent Inhibitors for the Simultaneous Inhibition of Protease and Helicase Activities of HCV NS3/4A Protease: A Computational Approach

Riaz, Muhammad ; Rehman, Ashfaq Ur ; Waqas, Muhammad ; Khalid, Asaad ; Abdalla, Ashraf N ; Mahmood, Arif ; Hu, Junjian ; Wadood, Abdul

Molecules (Basel, Switzerland), 2023-01, Vol.28 (3), p.1300 [Periódico revisado por pares]

Switzerland: MDPI AG

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3
Evaluation of interactions between the hepatitis C virus NS3/4A and sulfonamidobenzamide based molecules using molecular docking, molecular dynamics simulations and binding free energy calculations
Evaluation of interactions between the hepatitis C virus NS3/4A and sulfonamidobenzamide based molecules using molecular docking, molecular dynamics simulations and binding free energy calculations
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Evaluation of interactions between the hepatitis C virus NS3/4A and sulfonamidobenzamide based molecules using molecular docking, molecular dynamics simulations and binding free energy calculations

Ren, Jinhong ; Vaid, Tasneem M. ; Lee, Hyun ; Ojeda, Isabel ; Johnson, Michael E.

Journal of computer-aided molecular design, 2023, Vol.37 (1), p.53-65 [Periódico revisado por pares]

Cham: Springer International Publishing

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4
Impact of Preexisting Hepatitis C Virus Genotype 6 NS3, NS5A, and NS5B Polymorphisms on the In Vitro Potency of Direct-Acting Antiviral Agents
Impact of Preexisting Hepatitis C Virus Genotype 6 NS3, NS5A, and NS5B Polymorphisms on the In Vitro Potency of Direct-Acting Antiviral Agents
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Impact of Preexisting Hepatitis C Virus Genotype 6 NS3, NS5A, and NS5B Polymorphisms on the In Vitro Potency of Direct-Acting Antiviral Agents

McPhee, Fiona ; Ueland, Joseph ; Vellucci, Vincent ; Bowden, Scott ; Sievert, William ; Zhou, Nannan

Antimicrobial agents and chemotherapy, 2019-04, Vol.63 (4) [Periódico revisado por pares]

United States: American Society for Microbiology

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5
Daclatasvir plus simeprevir with or without ribavirin for the treatment of chronic hepatitis C virus genotype 1 infection
Daclatasvir plus simeprevir with or without ribavirin for the treatment of chronic hepatitis C virus genotype 1 infection
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Daclatasvir plus simeprevir with or without ribavirin for the treatment of chronic hepatitis C virus genotype 1 infection

Zeuzem, Stefan ; Hézode, Christophe ; Bronowicki, Jean-Pierre ; Loustaud-Ratti, Veronique ; Gea, Francisco ; Buti, Maria ; Olveira, Antonio ; Banyai, Tivadar ; Al-Assi, M. Tarek ; Petersen, Joerg ; Thabut, Dominique ; Gadano, Adrian ; Pruitt, Ronald ; Makara, Mihály ; Bourlière, Marc ; Pol, Stanislas ; Beumont-Mauviel, Maria ; Ouwerkerk-Mahadevan, Sivi ; Picchio, Gaston ; Bifano, Marc ; M Phee, Fiona ; Boparai, Navdeep ; Cheung, Kin ; Hughes, Eric A ; Noviello, Stephanie

Journal of hepatology, 2016-02, Vol.64 (2), p.292-300 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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6
Importin β1 targeting by hepatitis C virus NS3/4A protein restricts IRF3 and NF‐κB signaling of IFNB1 antiviral response
Importin β1 targeting by hepatitis C virus NS3/4A protein restricts IRF3 and NF‐κB signaling of IFNB1 antiviral response
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Importin β1 targeting by hepatitis C virus NS3/4A protein restricts IRF3 and NF‐κB signaling of IFNB1 antiviral response

Gagné, Bridget ; Tremblay, Nicolas ; Park, Alex Y. ; Baril, Martin ; Lamarre, Daniel

Traffic (Copenhagen, Denmark), 2017-06, Vol.18 (6), p.362-377 [Periódico revisado por pares]

Former Munksgaard: John Wiley & Sons A/S

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7
macrocyclic HCV NS3/4A protease inhibitor interacts with protease and helicase residues in the complex with its full-length target
macrocyclic HCV NS3/4A protease inhibitor interacts with protease and helicase residues in the complex with its full-length target
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macrocyclic HCV NS3/4A protease inhibitor interacts with protease and helicase residues in the complex with its full-length target

Schiering, Nikolaus ; D’Arcy, Allan ; Villard, Frederic ; Simić, Oliver ; Kamke, Marion ; Monnet, Gaby ; Hassiepen, Ulrich ; Svergun, Dmitri I ; Pulfer, Ruth ; Eder, Jörg ; Raman, Prakash ; Bodendorf, Ursula

Proceedings of the National Academy of Sciences - PNAS, 2011-12, Vol.108 (52), p.21052-21056 [Periódico revisado por pares]

United States: National Academy of Sciences

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8
Hepatitis C virus NS3 protein can activate the Notch-signaling pathway through binding to a transcription factor, SRCAP
Hepatitis C virus NS3 protein can activate the Notch-signaling pathway through binding to a transcription factor, SRCAP
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Hepatitis C virus NS3 protein can activate the Notch-signaling pathway through binding to a transcription factor, SRCAP

Iwai, Atsushi ; Takegami, Tsutomu ; Shiozaki, Takuya ; Miyazaki, Tadaaki Tavis, John E.

PloS one, 2011-06, Vol.6 (6), p.e20718-e20718 [Periódico revisado por pares]

United States: Public Library of Science

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9
The scavenger receptors SRA-1 and SREC-I cooperate with TLR2 in the recognition of the hepatitis C virus non-structural protein 3 by dendritic cells
The scavenger receptors SRA-1 and SREC-I cooperate with TLR2 in the recognition of the hepatitis C virus non-structural protein 3 by dendritic cells
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The scavenger receptors SRA-1 and SREC-I cooperate with TLR2 in the recognition of the hepatitis C virus non-structural protein 3 by dendritic cells

Beauvillain, Céline ; Meloni, Francesca ; Sirard, Jean-Claude ; Blanchard, Simon ; Jarry, Ulrich ; Scotet, Mari ; Magistrelli, Giovanni ; Delneste, Yves ; Barnaba, Vincenzo ; Jeannin, Pascale

Journal of hepatology, 2010-05, Vol.52 (5), p.644-651 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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10
Cell transformation induced by hepatitis C virus NS3 serine protease
Cell transformation induced by hepatitis C virus NS3 serine protease
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Cell transformation induced by hepatitis C virus NS3 serine protease

Zemel, R. ; Gerechet, S. ; Greif, H. ; Bachmatove, L. ; Birk, Y. ; Golan-Goldhirsh, A. ; Kunin, M. ; Berdichevsky, Y. ; Benhar, I. ; Tur-Kaspa, R.

Journal of viral hepatitis, 2001-03, Vol.8 (2), p.96-102 [Periódico revisado por pares]

Oxford UK: Blackwell Science Ltd

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