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1
Identification of dual PPARα/γ agonists and their effects on lipid metabolism
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Identification of dual PPARα/γ agonists and their effects on lipid metabolism

Gao, Quanqing ; Hanh, Jacky ; Váradi, Linda ; Cairns, Rose ; Sjöström, Helena ; Liao, Vivian W.Y. ; Wood, Peta ; Balaban, Seher ; Ong, Jennifer Ai ; Lin, Hsuan-Yu Jennifer ; Lai, Felcia ; Hoy, Andrew J. ; Grewal, Thomas ; Groundwater, Paul W. ; Hibbs, David E.

Bioorganic & Medicinal Chemistry, 12/2015, Vol.23(24), pp.7676-7684 [Periódico revisado por pares]

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2
Development of a novel class of potent and selective FIXa inhibitors
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Development of a novel class of potent and selective FIXa inhibitors

Zhang, Ting ; Andre, Patrick ; Bateman, Thomas J. ; Chen, Yi-Heng ; Desai, Kunal ; Ellsworth, Kenneth ; Geissler, Wayne M. ; Guo, Liangqin ; Hruza, Alan ; Jian, Tianying ; Meng, Dongfang ; Parker, Dann L. ; Qian, Xiaoxia ; Reichert, Paul ; Sherer, Edward C. ; Shu, Min ; Smith, Cameron J. ; Sonatore, Lisa M. ; Tschirret-Guth, Richard ; Nolting, Andrew F. ; Orr, Robert ; Campeau, Louis-Charles ; Araki, Kazuto ; Nishimura, Teruyuki ; Sakurada, Isao ; Wood, Harold B.

Bioorganic & Medicinal Chemistry Letters, 11/2015, Vol.25(21), pp.4945-4949 [Periódico revisado por pares]

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3
Initial development of a cytotoxic amino-seco-CBI warhead for delivery by prodrug systems
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Initial development of a cytotoxic amino-seco-CBI warhead for delivery by prodrug systems

Twum, Elvis A. ; Nathubhai, Amit ; Wood, Pauline J. ; Lloyd, Matthew D. ; Thompson, Andrew S. ; Threadgill, Michael D.

Bioorganic & Medicinal Chemistry, 07/2015, Vol.23(13), pp.3481-3489 [Periódico revisado por pares]

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4
Structure-based design, synthesis and evaluation in vitro of arylnaphthyridinones, arylpyridopyrimidinones and their tetrahydro derivatives as inhibitors of the tankyrases
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Structure-based design, synthesis and evaluation in vitro of arylnaphthyridinones, arylpyridopyrimidinones and their tetrahydro derivatives as inhibitors of the tankyrases

Kumpan, Katerina ; Nathubhai, Amit ; Zhang, Chenlu ; Wood, Pauline J. ; Lloyd, Matthew D. ; Thompson, Andrew S. ; Haikarainen, Teemu ; Lehtiö, Lari ; Threadgill, Michael D.

Bioorganic & Medicinal Chemistry, 07/2015, Vol.23(13), pp.3013-3032 [Periódico revisado por pares]

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5
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design and synthesis of novel, potent and orally bioavailable N-aryl piperazine-1-carboxamide CCR2 antagonists with very high hERG selectivity

Cumming , John G. ; Bower , Justin F. ; Waterson , David ; Faull , Alan ; Poyser , Philip J. ; Turner , Paul ; Mcdermott , Benjamin ; Campbell , Andrew D. ; Hudson , Julian ; James , Michael ; Winter , Jon ; Wood , Christine

Bioorganic & medicinal chemistry letters, 2012, Vol.22(12), pp.3895-3899 [Periódico revisado por pares]

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6
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Identification, optimisation and in vivo evaluation of oxadiazole DGAT-1 inhibitors for the treatment of obesity and diabetes

Mccoull , William ; Addie , Matthew S. ; Birch , Alan M. ; Birtles , Susan ; Buckett , Linda K. ; Butlin , Roger J. ; Bowker , Suzanne S. ; Boyd , Scott ; Chapman , Stephen ; Davies , Robert D.M. ; Donald , Craig S. ; Green , Clive P. ; Jenner , Chloe ; Kemmitt , Paul D. ; Leach , Andrew G. ; Moody , Graeme C. ; Morentin Gutierrez , Pablo ; Newcombe , Nicholas J. ; Nowak , Thorsten ; Packer , Martin J. ; Plowright , Alleyn T. ; Revill , John ; Schofield , Paul ; Sheldon , Chris ; Stokes , Steve ; Turnbull , Andrew V. ; Wang , Steven J.Y. ; Whalley , David P. ; Matthew Wood , J.

Bioorganic & medicinal chemistry letters, 2012, Vol.22(12), pp.3873-3878 [Periódico revisado por pares]

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7
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Targeting conserved water molecules: Design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization

Davies , Nicholas G.M. ; Browne , Helen ; Davis , Ben ; Drysdale , Martin J. ; Foloppe , Nicolas ; Geoffrey , Stephanie ; Gibbons , Ben ; Hart , Terance ; Hubbard , Roderick ; Jensen , Michael Rugaard ; Mansell , Howard ; Massey , Andrew ; Matassova , Natalia ; Moore , Jonathan D. ; Murray , James ; Pratt , Robert ; Ray , Stuart ; Robertson , Alan ; Roughley , Stephen D. ; Schoepfer , Joseph ; Scriven , Kirsten ; Simmonite , Heather ; Stokes , Stephen ; Surgenor , Allan ; Webb , Paul ; Wood , Mike ; Wright , Lisa ; Brough , Paul

Bioorganic & medicinal chemistry, 2012, Vol.20(22), pp.6770-6789 [Periódico revisado por pares]

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8
Studies towards the identification of a new generation of atypical antipsychotic agents
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Studies towards the identification of a new generation of atypical antipsychotic agents

Garzya, Vincenzo ; Forbes, Ian T. ; Gribble, Andrew D. ; Hadley, Mike S. ; Lightfoot, Andrew P. ; Payne, Andrew H. ; Smith, Alexander B. ; Douglas, Sara E. ; Cooper, David G. ; Stansfield, Ian G. ; Meeson, Malcom ; Dodds, Emma E. ; Jones, Declan N.C. ; Wood, Martyn ; Reavill, Charlie ; Scorer, Carol A. ; Worby, Angela ; Riley, Graham ; Eddershaw, Peter ; Ioannou, Chris ; Donati, Daniele ; Hagan, Jim J. ; Ratti, Emiliangelo A.

Bioorganic & Medicinal Chemistry Letters, 1/2007, Vol.17(2), pp.400-405 [Periódico revisado por pares]

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Deste Autor:

  1. Nathubhai, Amit
  2. Wood, Pauline J.
  3. Chapman, Stephen
  4. Winter, Jon
  5. Reavill, Charlie

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