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Dihydrolipoamide dehydrogenase, pyruvate oxidation, and acetylation-dependent mechanisms intersecting drug iatrogenesis
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Dihydrolipoamide dehydrogenase, pyruvate oxidation, and acetylation-dependent mechanisms intersecting drug iatrogenesis

Duarte, I. F. ; Caio, J. ; Moedas, M. F. ; Rodrigues, L. A. ; Leandro, A. P. ; Rivera, I. A. ; Silva, M. F. B.

Cellular and molecular life sciences : CMLS, 2021-12, Vol.78 (23), p.7451-7468 [Periódico revisado por pares]

Cham: Springer International Publishing

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Branched-chain ketoacid overload inhibits insulin action in the muscle
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Branched-chain ketoacid overload inhibits insulin action in the muscle

Biswas, Dipsikha ; Dao, Khoi T. ; Mercer, Angella ; Cowie, Andrew M. ; Duffley, Luke ; El Hiani, Yassine ; Kienesberger, Petra C. ; Pulinilkunnil, Thomas

The Journal of biological chemistry, 2020-11, Vol.295 (46), p.15597-15621 [Periódico revisado por pares]

United States: Elsevier Inc

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TGF-β1 is a regulator of the pyruvate dehydrogenase complex in fibroblasts
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TGF-β1 is a regulator of the pyruvate dehydrogenase complex in fibroblasts

Smith, Edward R ; Hewitson, Timothy D

Scientific reports, 2020-10, Vol.10 (1), p.17914, Article 17914 [Periódico revisado por pares]

England: Nature Publishing Group

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4
Reengineering of the human pyruvate dehydrogenase complex: from disintegration to highly active agglomerates
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Reengineering of the human pyruvate dehydrogenase complex: from disintegration to highly active agglomerates

Guo, Jin ; Hezaveh, Samira ; Tatur, Jana ; Zeng, An-Ping ; Jandt, Uwe

Biochemical journal, 2017-03, Vol.474 (5), p.865-875 [Periódico revisado por pares]

England: Portland Press Ltd

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5
Furan-based inhibitors of pyruvate dehydrogenase: SAR study, biochemical evaluation and computational analysis
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Furan-based inhibitors of pyruvate dehydrogenase: SAR study, biochemical evaluation and computational analysis

Chan, Alex H. Y ; Ho, Terence C. S ; Parle, Daniel R ; Leeper, Finian J

Organic & biomolecular chemistry, 2023-02, Vol.21 (8), p.1755-1763 [Periódico revisado por pares]

England: Royal Society of Chemistry

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6
Synthesis and antifungal activity of 5-iodo-1,4-disubstituted-1,2,3-triazole derivatives as pyruvate dehydrogenase complex E1 inhibitors
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Synthesis and antifungal activity of 5-iodo-1,4-disubstituted-1,2,3-triazole derivatives as pyruvate dehydrogenase complex E1 inhibitors

He, Jun-Bo ; He, Hai-Feng ; Zhao, Lu-Lu ; Zhang, Li ; You, Ge-Yun ; Feng, Ling-Ling ; Wan, Jian ; He, Hong-Wu

Bioorganic & medicinal chemistry, 2015-04, Vol.23 (7), p.1395-1401 [Periódico revisado por pares]

England: Elsevier Ltd

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7
Living related versus deceased donor liver transplantation for maple syrup urine disease
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Living related versus deceased donor liver transplantation for maple syrup urine disease

Feier, Flavia ; Schwartz, Ida Vanessa D. ; Benkert, Abigail R. ; Neto, Joao Seda ; Miura, Irene ; Chapchap, Paulo ; da Fonseca, Eduardo Antunes ; Vieira, Sandra ; Zanotelli, Maria Lúcia ; Vairo, Filippo Pinto e ; Camelo, Jose Simon ; Margutti, Ana Vitoria Barban ; Mazariegos, George V. ; Puffenberger, Erik G. ; Strauss, Kevin A.

Molecular genetics and metabolism, 2016-03, Vol.117 (3), p.336-343 [Periódico revisado por pares]

United States: Elsevier Inc

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8
Role of Lipoylation of the Immunodominant Epitope of Pyruvate Dehydrogenase Complex: Toward a Peptide-Based Diagnostic Assay for Primary Biliary Cirrhosis
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Role of Lipoylation of the Immunodominant Epitope of Pyruvate Dehydrogenase Complex: Toward a Peptide-Based Diagnostic Assay for Primary Biliary Cirrhosis

Pacini, Giulia ; Carotenuto, Alfonso ; Rentier, Cedric ; Nuti, Francesca ; Real-Fernandez, Feliciana ; Brancaccio, Diego ; Sabatino, Giuseppina ; Larregola, Maud ; Peroni, Elisa ; Migliorini, Paola ; Novellino, Ettore ; Battezzati, Pier Maria ; Selmi, Carlo ; Papini, Anna Maria ; Rovero, Paolo

Journal of medicinal chemistry, 2015-08, Vol.58 (16), p.6619-6629 [Periódico revisado por pares]

United States: American Chemical Society

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9
Structure-guided engineering of branched-chain α-keto acid decarboxylase for improved 1,2,4-butanetriol production by in vitro synthetic enzymatic biosystem
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Structure-guided engineering of branched-chain α-keto acid decarboxylase for improved 1,2,4-butanetriol production by in vitro synthetic enzymatic biosystem

Lv, Kemin ; Cao, Xuefei ; Pedroso, Marcelo Monteiro ; Wu, Bin ; Li, Jiahuang ; He, Bingfang ; Schenk, Gerhard

International journal of biological macromolecules, 2024-01, Vol.255, p.128303-128303, Article 128303 [Periódico revisado por pares]

Netherlands

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10
Structural and Biochemical Investigation of Selected Pathogenic Mutants of the Human Dihydrolipoamide Dehydrogenase
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Structural and Biochemical Investigation of Selected Pathogenic Mutants of the Human Dihydrolipoamide Dehydrogenase

Szabo, Eszter ; Nemes-Nikodem, Eva ; Vass, Krisztina Rubina ; Zambo, Zsofia ; Zrupko, Eszter ; Torocsik, Beata ; Ozohanics, Oliver ; Nagy, Balint ; Ambrus, Attila

International journal of molecular sciences, 2023-06, Vol.24 (13), p.10826 [Periódico revisado por pares]

Switzerland: MDPI AG

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