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Material Type: Artigo
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A cross-platform approach identifies genetic regulators of human metabolism and healthLotta, Luca A ; Pietzner, Maik ; Stewart, Isobel D ; Wittemans, Laura B L ; Li, Chen ; Bonelli, Roberto ; Raffler, Johannes ; Biggs, Emma K ; Oliver-Williams, Clare ; Auyeung, Victoria P W ; Luan, Jian'an ; Wheeler, Eleanor ; Paige, Ellie ; Surendran, Praveen ; Michelotti, Gregory A ; Scott, Robert A ; Burgess, Stephen ; Zuber, Verena ; Sanderson, Eleanor ; Koulman, Albert ; Imamura, Fumiaki ; Forouhi, Nita G ; Khaw, Kay-Tee ; Griffin, Julian L ; Wood, Angela M ; Kastenmüller, Gabi ; Danesh, John ; Butterworth, Adam S ; Gribble, Fiona M ; Reimann, Frank ; Bahlo, Melanie ; Fauman, Eric ; Wareham, Nicholas J ; Langenberg, ClaudiaNature genetics, 2021-01, Vol.53 (1), p.54-64 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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2 |
Material Type: Artigo
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Comparative effectiveness of sotrovimab and molnupiravir for prevention of severe covid-19 outcomes in patients in the community: observational cohort study with the OpenSAFELY platformZheng, Bang ; Green, Amelia C A ; Tazare, John ; Curtis, Helen J ; Fisher, Louis ; Nab, Linda ; Schultze, Anna ; Mahalingasivam, Viyaasan ; Parker, Edward P K ; Hulme, William J ; Bacon, Sebastian C J ; DeVito, Nicholas J ; Bates, Christopher ; Evans, David ; Inglesby, Peter ; Drysdale, Henry ; Davy, Simon ; Cockburn, Jonathan ; Morton, Caroline E ; Hickman, George ; Ward, Tom ; Smith, Rebecca M ; Parry, John ; Hester, Frank ; Harper, Sam ; Mehrkar, Amir ; Eggo, Rosalind M ; Walker, Alex J ; Evans, Stephen J W ; Douglas, Ian J ; MacKenna, Brian ; Goldacre, Ben ; Tomlinson, Laurie ABMJ (Online), 2022-11, Vol.379, p.e071932 [Periódico revisado por pares]England: British Medical Journal Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Association between living with children and outcomes from covid-19: OpenSAFELY cohort study of 12 million adults in EnglandForbes, Harriet ; Morton, Caroline E ; Bacon, Seb ; McDonald, Helen I ; Minassian, Caroline ; Brown, Jeremy P ; Rentsch, Christopher T ; Mathur, Rohini ; Schultze, Anna ; DeVito, Nicholas J ; MacKenna, Brian ; Hulme, William J ; Croker, Richard ; Walker, Alex J ; Williamson, Elizabeth J ; Bates, Chris ; Mehrkar, Amir ; Curtis, Helen J ; Evans, David ; Wing, Kevin ; Inglesby, Peter ; Drysdale, Henry ; Wong, Angel Y S ; Cockburn, Jonathan ; McManus, Robert ; Parry, John ; Hester, Frank ; Harper, Sam ; Douglas, Ian J ; Smeeth, Liam ; Evans, Stephen J W ; Bhaskaran, Krishnan ; Eggo, Rosalind M ; Goldacre, Ben ; Tomlinson, Laurie ABMJ (Online), 2021-03, Vol.372, p.n628-n628 [Periódico revisado por pares]England: BMJ Publishing Group LTDTexto completo disponível |
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Material Type: Artigo
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Sixty-five common genetic variants and prediction of type 2 diabetesTalmud, Philippa J ; Cooper, Jackie A ; Morris, Richard W ; Dudbridge, Frank ; Shah, Tina ; Engmann, Jorgen ; Dale, Caroline ; White, Jon ; McLachlan, Stela ; Zabaneh, Delilah ; Wong, Andrew ; Ong, Ken K ; Gaunt, Tom ; Holmes, Michael V ; Lawlor, Debbie A ; Richards, Marcus ; Hardy, Rebecca ; Kuh, Diana ; Wareham, Nicholas ; Langenberg, Claudia ; Ben-Shlomo, Yoav ; Wannamethee, S Goya ; Strachan, Mark W J ; Kumari, Meena ; Whittaker, John C ; Drenos, Fotios ; Kivimaki, Mika ; Hingorani, Aroon D ; Price, Jacqueline F ; Humphries, Steve EDiabetes (New York, N.Y.), 2015-05, Vol.64 (5), p.1830-1840 [Periódico revisado por pares]United States: American Diabetes AssociationTexto completo disponível |
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5 |
Material Type: Artigo
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Dietary Intake, FTO Genetic Variants, and Adiposity: A Combined Analysis of Over 16,000 Children and AdolescentsQi, Qibin ; Downer, Mary K ; Kilpeläinen, Tuomas O ; Taal, H Rob ; Barton, Sheila J ; Ntalla, Ioanna ; Standl, Marie ; Boraska, Vesna ; Huikari, Ville ; Kiefte-de Jong, Jessica C ; Körner, Antje ; Lakka, Timo A ; Liu, Gaifen ; Magnusson, Jessica ; Okuda, Masayuki ; Raitakari, Olli ; Richmond, Rebecca ; Scott, Robert A ; Bailey, Mark E S ; Scheuermann, Kathrin ; Holloway, John W ; Inskip, Hazel ; Isasi, Carmen R ; Mossavar-Rahmani, Yasmin ; Jaddoe, Vincent W V ; Laitinen, Jaana ; Lindi, Virpi ; Melén, Erik ; Pitsiladis, Yannis ; Pitkänen, Niina ; Snieder, Harold ; Heinrich, Joachim ; Timpson, Nicholas J ; Wang, Tao ; Yuji, Hinoda ; Zeggini, Eleftheria ; Dedoussis, George V ; Kaplan, Robert C ; Wylie-Rosett, Judith ; Loos, Ruth J F ; Hu, Frank B ; Qi, LuDiabetes (New York, N.Y.), 2015-07, Vol.64 (7), p.2467-2476 [Periódico revisado por pares]United States: American Diabetes AssociationTexto completo disponível |
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Material Type: Artigo
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Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposityCousminer, Diana L ; Berry, Diane J ; Timpson, Nicholas J ; Ang, Wei ; Thiering, Elisabeth ; Byrne, Enda M ; Taal, H Rob ; Huikari, Ville ; Bradfield, Jonathan P ; Kerkhof, Marjan ; Groen-Blokhuis, Maria M ; Kreiner-Møller, Eskil ; Marinelli, Marcella ; Holst, Claus ; Leinonen, Jaakko T ; Perry, John R B ; Surakka, Ida ; Pietiläinen, Olli ; Kettunen, Johannes ; Anttila, Verneri ; Kaakinen, Marika ; Sovio, Ulla ; Pouta, Anneli ; Das, Shikta ; Lagou, Vasiliki ; Power, Chris ; Prokopenko, Inga ; Evans, David M ; Kemp, John P ; St Pourcain, Beate ; Ring, Susan ; Palotie, Aarno ; Kajantie, Eero ; Osmond, Clive ; Lehtimäki, Terho ; Viikari, Jorma S ; Kähönen, Mika ; Warrington, Nicole M ; Lye, Stephen J ; Palmer, Lyle J ; Tiesler, Carla M T ; Flexeder, Claudia ; Montgomery, Grant W ; Medland, Sarah E ; Hofman, Albert ; Hakonarson, Hakon ; Guxens, Mònica ; Bartels, Meike ; Salomaa, Veikko ; Murabito, Joanne M ; Kaprio, Jaakko ; Sørensen, Thorkild I A ; Ballester, Ferran ; Bisgaard, Hans ; Boomsma, Dorret I ; Koppelman, Gerard H ; Grant, Struan F A ; Jaddoe, Vincent W V ; Martin, Nicholas G ; Heinrich, Joachim ; Pennell, Craig E ; Raitakari, Olli T ; Eriksson, Johan G ; Smith, George Davey ; Hyppönen, Elina ; Järvelin, Marjo-Riitta ; McCarthy, Mark I ; Ripatti, Samuli ; Widén, ElisabethHuman molecular genetics, 2013-07, Vol.22 (13), p.2735-2747 [Periódico revisado por pares]England: Oxford University PressTexto completo disponível |
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Material Type: Artigo
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Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistanceLotta, Luca A ; Gulati, Pawan ; Day, Felix R ; Payne, Felicity ; Ongen, Halit ; van de Bunt, Martijn ; Gaulton, Kyle J ; Eicher, John D ; Sharp, Stephen J ; Luan, Jian'an ; De Lucia Rolfe, Emanuella ; Stewart, Isobel D ; Wheeler, Eleanor ; Willems, Sara M ; Adams, Claire ; Yaghootkar, Hanieh ; Forouhi, Nita G ; Khaw, Kay-Tee ; Johnson, Andrew D ; Semple, Robert K ; Frayling, Timothy ; Perry, John R B ; Dermitzakis, Emmanouil ; McCarthy, Mark I ; Barroso, Inês ; Wareham, Nicholas J ; Savage, David B ; Langenberg, Claudia ; O'Rahilly, Stephen ; Scott, Robert ANature genetics, 2017-01, Vol.49 (1), p.17-26 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic DysregulationsMilaneschi, Yuri ; Lamers, Femke ; Peyrot, Wouter J ; Baune, Bernhard T ; Breen, Gerome ; Dehghan, Abbas ; Forstner, Andreas J ; Grabe, Hans J ; Homuth, Georg ; Kan, Carol ; Lewis, Cathryn ; Mullins, Niamh ; Nauck, Matthias ; Pistis, Giorgio ; Preisig, Martin ; Rivera, Margarita ; Rietschel, Marcella ; Streit, Fabian ; Strohmaier, Jana ; Teumer, Alexander ; Van der Auwera, Sandra ; Wray, Naomi R ; Boomsma, Dorret I ; Penninx, Brenda W. J. HJAMA psychiatry (Chicago, Ill.), 2017-12, Vol.74 (12), p.1214-1225 [Periódico revisado por pares]United States: American Medical AssociationTexto completo disponível |
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Material Type: Artigo
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Dietary fibre and incidence of type 2 diabetes in eight European countries: the EPIC-InterAct Study and a meta-analysis of prospective studiesKuijsten, ADiabetologia, 2015-07, Vol.58 (7), p.1394-1408 [Periódico revisado por pares]Berlin/Heidelberg: Springer Berlin HeidelbergTexto completo disponível |
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Material Type: Artigo
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A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistanceMANNING, Alisak ; HIVERT, Marie-France ; AMIN, Najaf ; BARNES, Daniel ; CADBY, Gemma ; HOTTENGA, Jouke-Jan ; INGELSSON, Erik ; JACKSON, Anne U ; JOHNSON, Toby ; KANONI, Stavroula ; LADENVALL, Claes ; LAGOU, Vasiliki ; SCOTT, Robert A ; LAHTI, Jari ; LECOEUR, Cecile ; YONGMEI LIU ; TERESA MARTINEZ-LARRAD, Maria ; MONTASSER, May E ; NAVARRO, Pau ; PERRY, John R. B ; RASMUSSEN-TORVIK, Laura J ; SALO, Perttu ; SATTAR, Naveed ; GRIMSBY, Jonnal ; SHUNGIN, Dmitry ; STRAWBRIDGE, Rona J ; TANAKA, Toshiko ; DUIJN, Cornelia M.van ; PING AN ; DE ANDRADE, Mariza ; ANDREWS, Jeanette S ; ASPELUND, Thor ; ATALAY, Mustafa ; AULCHENKO, Yurii ; BOUATIA-NAJI, Nabila ; BALKAU, Beverley ; BANDINELLI, Stefania ; BECKMANN, Jacquess ; BEILBY, John P ; BELLIS, Claire ; BERGMAN, Richard N ; BLANGERO, John ; BOBAN, Mladen ; BOEHNKE, Michael ; BOERWINKLE, Eric ; HAN CHEN ; BONNYCASTLE, Lori L ; BOOMSMA, Dorret I ; BORECKI, Ingrid B ; BÖTTCHER, Yvonne ; BOUCHARD, Claude ; BRUNNER, Eric ; BUDIMIR, Danijela ; CAMPBELL, Harry ; CARLSON, Olga ; CHINES, Peter S ; RYBIN, Denis ; LIU, Ching-Ti ; BIELAK, Lawrence F ; PROKOPENKO, IngaNature genetics, 2012-06, Vol.44 (6), p.659-669 [Periódico revisado por pares]New York, NY: Nature Publishing GroupTexto completo disponível |