Result Number | Material Type | Add to My Shelf Action | Record Details and Options |
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1 |
Material Type: Artigo
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The beta secretase BACE1 regulates the expression of insulin receptor in the liverMeakin, Paul J ; Mezzapesa, Anna ; Benabou, Eva ; Haas, Mary E ; Bonardo, Bernadette ; Grino, Michel ; Brunel, Jean-Michel ; Desbois-Mouthon, Christèle ; Biddinger, Sudha B ; Govers, Roland ; Ashford, Michael L J ; Peiretti, FranckNature communications, 2018-04, Vol.9 (1), p.1306-14, Article 1306 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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2 |
Material Type: Artigo
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Loss of Nrf2 markedly exacerbates nonalcoholic steatohepatitisChowdhry, Sudhir ; Nazmy, Maiiada H. ; Meakin, Paul J. ; Dinkova-Kostova, Albena T. ; Walsh, Shaun V. ; Tsujita, Tadayuki ; Dillon, John F. ; Ashford, Michael L.J. ; Hayes, John D.Free radical biology & medicine, 2010-01, Vol.48 (2), p.357-371 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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3 |
Material Type: Artigo
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Dimethyl fumarate blocks pro-inflammatory cytokine production via inhibition of TLR induced M1 and K63 ubiquitin chain formationMcGuire, Victoria A ; Ruiz-Zorrilla Diez, Tamara ; Emmerich, Christoph H ; Strickson, Sam ; Ritorto, Maria Stella ; Sutavani, Ruhcha V ; Weiβ, Anne ; Houslay, Kirsty F ; Knebel, Axel ; Meakin, Paul J ; Phair, Iain R ; Ashford, Michael L J ; Trost, Matthias ; Arthur, J Simon CScientific reports, 2016-08, Vol.6 (1), p.31159-31159, Article 31159 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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4 |
Material Type: Artigo
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Reduction in BACE1 decreases body weight, protects against diet-induced obesity and enhances insulin sensitivity in miceMeakin, Paul J ; Harper, Alex J ; Hamilton, D Lee ; Gallagher, Jennifer ; McNeilly, Alison D ; Burgess, Laura A ; Vaanholt, Lobke M ; Bannon, Kirsten A ; Latcham, Judy ; Hussain, Ishrut ; Speakman, John R ; Howlett, David R ; Ashford, Michael L JBiochemical journal, 2012-01, Vol.441 (1), p.285-296 [Periódico revisado por pares]England: Portland Press LtdTexto completo disponível |
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5 |
Material Type: Artigo
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The unfolded protein response is activated in skeletal muscle by high-fat feeding: potential role in the downregulation of protein synthesisDeldicque, Louise ; Cani, Patrice D ; Philp, Andrew ; Raymackers, Jean-Marc ; Meakin, Paul J ; Ashford, Michael L J ; Delzenne, Nathalie M ; Francaux, Marc ; Baar, KeithAmerican journal of physiology: endocrinology and metabolism, 2010-11, Vol.299 (5), p.E695-E705 [Periódico revisado por pares]United States: American Physiological SocietyTexto completo disponível |
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6 |
Material Type: Artigo
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Non-canonical Keap1-independent activation of Nrf2 in astrocytes by mild oxidative stressAl-Mubarak, Bashayer R. ; Bell, Karen F.S. ; Chowdhry, Sudhir ; Meakin, Paul J. ; Baxter, Paul S. ; McKay, Sean ; Dando, Owen ; Ashford, Michael L.J. ; Gazaryan, Irina ; Hayes, John D. ; Hardingham, Giles E.Redox biology, 2021-11, Vol.47, p.102158, Article 102158 [Periódico revisado por pares]Netherlands: Elsevier B.VTexto completo disponível |
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7 |
Material Type: Artigo
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Bace1-dependent amyloid processing regulates hypothalamic leptin sensitivity in obese miceMeakin, Paul J ; Jalicy, Susan M ; Montagut, Gemma ; Allsop, David J P ; Cavellini, Daniella L ; Irvine, Stuart W ; McGinley, Christopher ; Liddell, Mary K ; McNeilly, Alison D ; Parmionova, Karolina ; Liu, Yu-Ru ; Bailey, Charlotte L S ; Dale, J Kim ; Heisler, Lora K ; McCrimmon, Rory J ; Ashford, Michael L JScientific reports, 2018-01, Vol.8 (1), p.55-55, Article 55 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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8 |
Material Type: Artigo
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Mice Lacking beta2-Integrin Function Remain Glucose Tolerant in Spite of Insulin Resistance, Neutrophil Infiltration and InflammationMeakin, Paul J ; Morrison, Vicky L ; Sneddon, Claire C ; Savinko, Terhi ; Uotila, Liisa ; Jalicy, Susan M ; Gabriel, Jennie L ; Kang, Li ; Ashford, Michael L J ; Fagerholm, Susanna C Chen, XiaoliPloS one, 2015-09, Vol.10 (9), p.e0138872-e0138872 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
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9 |
Material Type: Artigo
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Nrf2 target genes can be controlled by neuronal activity in the absence of Nrf2 and astrocytesDeighton, Ruth F ; Márkus, Nóra M ; Al-Mubarak, Bashayer ; Bell, Karen F S ; Papadia, Sofia ; Meakin, Paul J ; Chowdhry, Sudhir ; Hayes, John D ; Hardingham, Giles EProceedings of the National Academy of Sciences - PNAS, 2014-05, Vol.111 (18), p.E1818-E1820 [Periódico revisado por pares]United States: National Acad SciencesTexto completo disponível |
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10 |
Material Type: Artigo
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Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1Mills, Evanna L ; Ryan, Dylan G ; Prag, Hiran A ; Dikovskaya, Dina ; Menon, Deepthi ; Zaslona, Zbigniew ; Jedrychowski, Mark P ; Costa, Ana S H ; Higgins, Maureen ; Hams, Emily ; Szpyt, John ; Runtsch, Marah C ; King, Martin S ; McGouran, Joanna F ; Fischer, Roman ; Kessler, Benedikt M ; McGettrick, Anne F ; Hughes, Mark M ; Carroll, Richard G ; Booty, Lee M ; Knatko, Elena V ; Meakin, Paul J ; Ashford, Michael L J ; Modis, Louise K ; Brunori, Gino ; Sévin, Daniel C ; Fallon, Padraic G ; Caldwell, Stuart T ; Kunji, Edmund R S ; Chouchani, Edward T ; Frezza, Christian ; Dinkova-Kostova, Albena T ; Hartley, Richard C ; Murphy, Michael P ; O'Neill, Luke ANature (London), 2018-04, Vol.556 (7699), p.113-117 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |