Result Number | Material Type | Add to My Shelf Action | Record Details and Options |
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1 |
Material Type: Livro
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Direct and allosteric control of glutamate receptorsMichael G Palfreyman; Ian J Reynolds; Phil SkolnickBoca Raton CRC Press c1994Localização: ICB - Inst. Ciências Biomédicas (QV4 C911d 1994 )(Acessar) |
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2 |
Material Type: Livro
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Allosteric modulation of amino acid receptors therapeutic implicationsEric A Barnard 1927-; Erminio Costa; Fidia Research FoundationNew York Raven Press c1989Localização: FFCLRP - Fac. Fil. Ciên. Let. de R. Preto (615 B259a 16194 ) e outros locais(Acessar) |
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3 |
Material Type: Artigo
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Synergy between l-DOPA and a novel positive allosteric modulator of metabotropic glutamate receptor 4: Implications for Parkinson's disease treatment and dyskinesiaBennouar, Khaled-Ezaheir ; Uberti, Michelle A. ; Melon, Christophe ; Bacolod, Maria D. ; Jimenez, Hermogenes N. ; Cajina, Manuel ; Kerkerian-Le Goff, Lydia ; Doller, Darío ; Gubellini, PaoloNeuropharmacology, 2013-03, Vol.66, p.158-169 [Periódico revisado por pares]England: Elsevier LtdTexto completo disponível |
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4 |
Material Type: Artigo
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Higher ambient synaptic glutamate at inhibitory versus excitatory neurons differentially impacts NMDA receptor activityYao, Lulu ; Grand, Teddy ; Hanson, Jesse E ; Paoletti, Pierre ; Zhou, QiangNature communications, 2018-10, Vol.9 (1), p.4000-13, Article 4000 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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5 |
Material Type: Artigo
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A computational approach yields selective inhibitors of human excitatory amino acid transporter 2 (EAAT2)Damm-Ganamet, Kelly L. ; Rives, Marie-Laure ; Wickenden, Alan D. ; McAllister, Heather M. ; Mirzadegan, TaranehThe Journal of biological chemistry, 2020-03, Vol.295 (13), p.4359-4366 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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6 |
Material Type: Artigo
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Understanding Exposure-Receptor Occupancy Relationships for Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators across a Range of Preclinical and Clinical StudiesBennett, Kirstie A ; Sergeev, Eugenia ; MacSweeney, Cliona P ; Bakker, Geor ; Cooper, Anne EThe Journal of pharmacology and experimental therapeutics, 2021-04, Vol.377 (1), p.157-168 [Periódico revisado por pares]United StatesTexto completo disponível |
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7 |
Material Type: Artigo
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Evaluation of Amides, Carbamates, Sulfonamides, and Ureas of 4‑Prop-2-ynylidenecycloalkylamine as Potent, Selective, and Bioavailable Negative Allosteric Modulators of Metabotropic Glutamate Receptor 5Graziani, Davide ; Caligari, Silvia ; Callegari, Elisa ; De Toma, Carlo ; Longhi, Matteo ; Frigerio, Fabio ; Dilernia, Roberto ; Menegon, Sergio ; Pinzi, Luca ; Pirona, Lorenza ; Tazzari, Valerio ; Valsecchi, Anna Elisa ; Vistoli, Giulio ; Rastelli, Giulio ; Riva, CarloJournal of medicinal chemistry, 2019-02, Vol.62 (3), p.1246-1273 [Periódico revisado por pares]United States: American Chemical SocietyTexto completo disponível |
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8 |
Material Type: Artigo
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Mechanism based neurotoxicity of mGlu5 positive allosteric modulators – Development challenges for a promising novel antipsychotic targetParmentier-Batteur, Sophie ; Hutson, Peter H. ; Menzel, Karsten ; Uslaner, Jason M. ; Mattson, Britta A. ; O'Brien, Julie A. ; Magliaro, Brian C. ; Forest, Thomas ; Stump, Craig A. ; Tynebor, Robert M. ; Anthony, Neville J. ; Tucker, Thomas J. ; Zhang, Xu-Fang ; Gomez, Robert ; Huszar, Sarah L. ; Lambeng, Nathalie ; Fauré, H. ; Le Poul, Emannuel ; Poli, Sonia ; Rosahl, Thomas W. ; Rocher, Jean-Philippe ; Hargreaves, Richard ; Williams, Theresa M.Neuropharmacology, 2014-07, Vol.82, p.161-173 [Periódico revisado por pares]England: Elsevier LtdTexto completo disponível |
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9 |
Material Type: Artigo
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In vitro characterisation of the novel positive allosteric modulators of the mGlu5 receptor, LSN2463359 and LSN2814617, and their effects on sleep architecture and operant responding in the ratGilmour, Gary ; Broad, Lisa M. ; Wafford, Keith A. ; Britton, Thomas ; Colvin, Ellen M. ; Fivush, Adam ; Gastambide, Francois ; Getman, Brian ; Heinz, Beverly A. ; McCarthy, Andrew P. ; Prieto, Lourdes ; Shanks, Elaine ; Smith, Janice W. ; Taboada, Lorena ; Edgar, Dale M. ; Tricklebank, Mark D.Neuropharmacology, 2013-01, Vol.64, p.224-239 [Periódico revisado por pares]England: Elsevier LtdTexto completo disponível |
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10 |
Material Type: Artigo
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Chemical Switch of a Metabotropic Glutamate Receptor 2 Silent Allosteric Modulator into Dual Metabotropic Glutamate Receptor 2/3 Negative/Positive Allosteric ModulatorsSchann, Stephan ; Mayer, Stanislas ; Franchet, Christel ; Frauli, Mélanie ; Steinberg, Edith ; Thomas, Mireille ; Baron, Luc ; Neuville, PascalJournal of medicinal chemistry, 2010-12, Vol.53 (24), p.8775-8779 [Periódico revisado por pares]United States: American Chemical SocietyTexto completo disponível |