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Reaction Phenotyping
Reaction Phenotyping
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Reaction Phenotyping

Hurst, Susan ; Williams, J. Andrew ; Hansel, Steven Zhang, Donglu ; Humphreys, W. Griffith ; Zhu, Mingshe

Drug Metabolism in Drug Design and Development, 2007, p.477-512

Hoboken, NJ, USA: John Wiley & Sons, Inc

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2
Use of Biomarker in Drug Development—Japanese Perspectives
Use of Biomarker in Drug Development—Japanese Perspectives
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Use of Biomarker in Drug Development—Japanese Perspectives

Uyama, Yoshiaki ; Ishiguro, Akihiro ; Nakamura, Harumasa ; Toyoshima, Satoshi Williams, J. Andrew ; Christ, David D ; Koup, Jeffrey R ; Lalonde, Richard

Predictive Approaches in Drug Discovery and Development, 2012, p.269-287

Hoboken, NJ, USA: John Wiley & Sons, Inc

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3
Cardiovascular Biomarkers as Examples of Success and Failure in Predicting Safety in Humans
Cardiovascular Biomarkers as Examples of Success and Failure in Predicting Safety in Humans
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Cardiovascular Biomarkers as Examples of Success and Failure in Predicting Safety in Humans

Authier, Simon ; Pugsley, Michael K ; Troncy, Eric ; Curtis, Michael J Williams, J. Andrew ; Christ, David D ; Koup, Jeffrey R ; Lalonde, Richard

Predictive Approaches in Drug Discovery and Development, 2012, p.163-188

Hoboken, NJ, USA: John Wiley & Sons, Inc

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4
In Vitro–In Vivo Correlations in Drug Discovery and Development: Concepts and Applications in Toxicology
In Vitro–In Vivo Correlations in Drug Discovery and Development: Concepts and Applications in Toxicology
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In Vitro–In Vivo Correlations in Drug Discovery and Development: Concepts and Applications in Toxicology

Denton, Rex ; Brannen, Kimberly ; Car, Bruce D Williams, J. Andrew ; Christ, David D ; Koup, Jeffrey R ; Lalonde, Richard

Predictive Approaches in Drug Discovery and Development, 2012, p.331-351

Hoboken, NJ, USA: John Wiley & Sons, Inc

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5
Biosensors for Clinical Biomarkers
Biosensors for Clinical Biomarkers
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Biosensors for Clinical Biomarkers

Tombelli, Sara ; Mascini, Marco Williams, J. Andrew ; Christ, David D ; Koup, Jeffrey R ; Lalonde, Richard

Predictive Approaches in Drug Discovery and Development, 2012, p.203-227

Hoboken, NJ, USA: John Wiley & Sons, Inc

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6
Validation of Biochemical Biomarker Assays used in Drug Discovery and Development: A Review of Challenges and Solutions
Validation of Biochemical Biomarker Assays used in Drug Discovery and Development: A Review of Challenges and Solutions
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Validation of Biochemical Biomarker Assays used in Drug Discovery and Development: A Review of Challenges and Solutions

Szekely‐Klepser, Gabriella ; Fountain, Scott Williams, J. Andrew ; Christ, David D ; Koup, Jeffrey R ; Lalonde, Richard

Predictive Approaches in Drug Discovery and Development, 2012, p.23-48

Hoboken, NJ, USA: John Wiley & Sons, Inc

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7
In Vitro–In Vivo Correlations of Hepatic Drug Clearance
In Vitro–In Vivo Correlations of Hepatic Drug Clearance
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In Vitro–In Vivo Correlations of Hepatic Drug Clearance

Obach, R. Scott Williams, J. Andrew ; Christ, David D ; Koup, Jeffrey R ; Lalonde, Richard

Predictive Approaches in Drug Discovery and Development, 2012, p.289-306

Hoboken, NJ, USA: John Wiley & Sons, Inc

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8
The Importance of Biomarkers in Translational Medicine
The Importance of Biomarkers in Translational Medicine
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The Importance of Biomarkers in Translational Medicine

Fleishaker, Joseph C Williams, J. Andrew ; Christ, David D ; Koup, Jeffrey R ; Lalonde, Richard

Predictive Approaches in Drug Discovery and Development, 2012, p.1-22

Hoboken, NJ, USA: John Wiley & Sons, Inc

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9
Overview of Metabolomics Basics
Overview of Metabolomics Basics
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Overview of Metabolomics Basics

Xu, Qiuwei ; Schaefer, William H Williams, J. Andrew ; Christ, David D ; Koup, Jeffrey R ; Lalonde, Richard

Predictive Approaches in Drug Discovery and Development, 2012, p.79-137

Hoboken, NJ, USA: John Wiley & Sons, Inc

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10
The Potential of In Silico and In Vitro Approaches to Predict In Vivo Drug–Drug Interactions and ADMET/TOX Properties
The Potential of In Silico and In Vitro Approaches to Predict In Vivo Drug–Drug Interactions and ADMET/TOX Properties
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The Potential of In Silico and In Vitro Approaches to Predict In Vivo Drug–Drug Interactions and ADMET/TOX Properties

Bachmann, Kenneth ; Ekins, Sean Williams, J. Andrew ; Christ, David D ; Koup, Jeffrey R ; Lalonde, Richard

Predictive Approaches in Drug Discovery and Development, 2012, p.307-329

Hoboken, NJ, USA: John Wiley & Sons, Inc

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