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Refinado por: Nome da Publicação: PLoS One remover
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1
Alpha-synuclein induces lysosomal rupture and cathepsin dependent reactive oxygen species following endocytosis
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Alpha-synuclein induces lysosomal rupture and cathepsin dependent reactive oxygen species following endocytosis

Freeman, David ; Cedillos, Rudy ; Choyke, Samantha ; Lukic, Zana ; McGuire, Kathleen ; Marvin, Shauna ; Burrage, Andrew M ; Sudholt, Stacey ; Rana, Ajay ; O'Connor, Christopher ; Wiethoff, Christopher M ; Campbell, Edward M Kahle, Philipp J.

PloS one, 2013-04, Vol.8 (4), p.e62143-e62143 [Periódico revisado por pares]

United States: Public Library of Science

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2
SNCA triplication Parkinson's patient's iPSC-derived DA neurons accumulate α-synuclein and are susceptible to oxidative stress
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SNCA triplication Parkinson's patient's iPSC-derived DA neurons accumulate α-synuclein and are susceptible to oxidative stress

Byers, Blake ; Cord, Branden ; Nguyen, Ha Nam ; Schüle, Birgitt ; Fenno, Lief ; Lee, Patrick C ; Deisseroth, Karl ; Langston, J William ; Pera, Renee Reijo ; Palmer, Theo D Chin, Wei-Chun

PloS one, 2011-11, Vol.6 (11), p.e26159-e26159 [Periódico revisado por pares]

United States: Public Library of Science

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3
Abberant alpha-synuclein confers toxicity to neurons in part through inhibition of chaperone-mediated autophagy
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Abberant alpha-synuclein confers toxicity to neurons in part through inhibition of chaperone-mediated autophagy

Xilouri, Maria ; Vogiatzi, Tereza ; Vekrellis, Kostas ; Park, David ; Stefanis, Leonidas Gendelman, Howard E.

PloS one, 2009-05, Vol.4 (5), p.e5515 [Periódico revisado por pares]

United States: Public Library of Science

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4
Preclinical development of a vaccine against oligomeric alpha-synuclein based on virus-like particles
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Preclinical development of a vaccine against oligomeric alpha-synuclein based on virus-like particles

Doucet, Marika ; El-Turabi, Aadil ; Zabel, Franziska ; Hunn, Benjamin H M ; Bengoa-Vergniory, Nora ; Cioroch, Milena ; Ramm, Mauricio ; Smith, Amy M ; Gomes, Ariane Cruz ; Cabral de Miranda, Gustavo ; Wade-Martins, Richard ; Bachmann, Martin F Kahle, Philipp J.

PloS one, 2017-08, Vol.12 (8), p.e0181844 [Periódico revisado por pares]

United States: Public Library of Science

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5
Formation of toxic oligomeric alpha-synuclein species in living cells
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Formation of toxic oligomeric alpha-synuclein species in living cells

Outeiro, Tiago Fleming ; Putcha, Preeti ; Tetzlaff, Julie E ; Spoelgen, Robert ; Koker, Mirjam ; Carvalho, Filipe ; Hyman, Bradley T ; McLean, Pamela J Koutsopoulos, Sotirios

PloS one, 2008-04, Vol.3 (4), p.e1867 [Periódico revisado por pares]

United States: Public Library of Science

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6
Aggregated Alpha-Synuclein Transfer Efficiently between Cultured Human Neuron-Like Cells and Localize to Lysosomes
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Aggregated Alpha-Synuclein Transfer Efficiently between Cultured Human Neuron-Like Cells and Localize to Lysosomes

Domert, Jakob ; Sackmann, Christopher ; Severinsson, Emelie ; Agholme, Lotta ; Bergström, Joakim ; Ingelsson, Martin ; Hallbeck, Martin Witt, Stephan N.

PloS one, 2016-12, Vol.11 (12), p.e0168700-e0168700 [Periódico revisado por pares]

United States: Public Library of Science

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7
Alpha-Synuclein Proteins Promote Pro-Inflammatory Cascades in Microglia: Stronger Effects of the A53T Mutant
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Alpha-Synuclein Proteins Promote Pro-Inflammatory Cascades in Microglia: Stronger Effects of the A53T Mutant

Hoenen, Claire ; Gustin, Audrey ; Birck, Cindy ; Kirchmeyer, Mélanie ; Beaume, Nicolas ; Felten, Paul ; Grandbarbe, Luc ; Heuschling, Paul ; Heurtaux, Tony Nataf, Serge

PloS one, 2016-09, Vol.11 (9), p.e0162717-e0162717 [Periódico revisado por pares]

United States: Public Library of Science

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8
Tau enhances α-synuclein aggregation and toxicity in cellular models of synucleinopathy
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Tau enhances α-synuclein aggregation and toxicity in cellular models of synucleinopathy

Badiola, Nahuai ; de Oliveira, Rita Machado ; Herrera, Federico ; Guardia-Laguarta, Cristina ; Gonçalves, Susana A ; Pera, Marta ; Suárez-Calvet, Marc ; Clarimon, Jordi ; Outeiro, Tiago Fleming ; Lleó, Alberto Iijima, Koichi M.

PloS one, 2011-10, Vol.6 (10), p.e26609 [Periódico revisado por pares]

United States: Public Library of Science

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9
CpG demethylation enhances alpha-synuclein expression and affects the pathogenesis of Parkinson's disease
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CpG demethylation enhances alpha-synuclein expression and affects the pathogenesis of Parkinson's disease

Matsumoto, Lumine ; Takuma, Hiroshi ; Tamaoka, Akira ; Kurisaki, Hiroshi ; Date, Hidetoshi ; Tsuji, Shoji ; Iwata, Atsushi Feany, Mel B.

PloS one, 2010-11, Vol.5 (11), p.e15522 [Periódico revisado por pares]

United States: Public Library of Science

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10
Bacterial Chaperones CsgE and CsgC Differentially Modulate Human α-Synuclein Amyloid Formation via Transient Contacts
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Bacterial Chaperones CsgE and CsgC Differentially Modulate Human α-Synuclein Amyloid Formation via Transient Contacts

Chorell, Erik ; Andersson, Emma ; Evans, Margery L ; Jain, Neha ; Götheson, Anna ; Åden, Jörgen ; Chapman, Matthew R ; Almqvist, Fredrik ; Wittung-Stafshede, Pernilla Baskakov, Ilia V

PloS one, 2015, Vol.10 (10), p.e0140194-e0140194 [Periódico revisado por pares]

United States: Public Library of Science

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