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Refinado por: assunto: Anatomy & Physiology remover Nome da Publicação: Bioorganic and Medicinal Chemistry remover
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1
Identification of dual PPARα/γ agonists and their effects on lipid metabolism
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Identification of dual PPARα/γ agonists and their effects on lipid metabolism

Gao, Quanqing ; Hanh, Jacky ; Váradi, Linda ; Cairns, Rose ; Sjöström, Helena ; Liao, Vivian W.Y. ; Wood, Peta ; Balaban, Seher ; Ong, Jennifer Ai ; Lin, Hsuan-Yu Jennifer ; Lai, Felcia ; Hoy, Andrew J. ; Grewal, Thomas ; Groundwater, Paul W. ; Hibbs, David E.

Bioorganic & Medicinal Chemistry, 12/2015, Vol.23(24), pp.7676-7684 [Periódico revisado por pares]

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Exploration of the nicotinamide-binding site of the tankyrases, identifying 3-arylisoquinolin-1-ones as potent and selective inhibitors in vitro
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Exploration of the nicotinamide-binding site of the tankyrases, identifying 3-arylisoquinolin-1-ones as potent and selective inhibitors in vitro

Paine, Helen A. ; Nathubhai, Amit ; Woon, Esther C.Y. ; Sunderland, Peter T. ; Wood, Pauline J. ; Mahon, Mary F. ; Lloyd, Matthew D. ; Thompson, Andrew S. ; Haikarainen, Teemu ; Narwal, Mohit ; Lehtiö, Lari ; Threadgill, Michael D.

Bioorganic & Medicinal Chemistry, 09/2015, Vol.23(17), pp.5891-5908 [Periódico revisado por pares]

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3
Initial development of a cytotoxic amino- seco -CBI warhead for delivery by prodrug systems
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Initial development of a cytotoxic amino- seco -CBI warhead for delivery by prodrug systems

Twum, Elvis A. ; Nathubhai, Amit ; Wood, Pauline J. ; Lloyd, Matthew D. ; Thompson, Andrew S. ; Threadgill, Michael D.

Bioorganic & Medicinal Chemistry, 07/2015, Vol.23(13), pp.3481-3489 [Periódico revisado por pares]

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4
Structure-based design, synthesis and evaluation in vitro of arylnaphthyridinones, arylpyridopyrimidinones and their tetrahydro derivatives as inhibitors of the tankyrases
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Structure-based design, synthesis and evaluation in vitro of arylnaphthyridinones, arylpyridopyrimidinones and their tetrahydro derivatives as inhibitors of the tankyrases

Kumpan, Katerina ; Nathubhai, Amit ; Zhang, Chenlu ; Wood, Pauline J. ; Lloyd, Matthew D. ; Thompson, Andrew S. ; Haikarainen, Teemu ; Lehtiö, Lari ; Threadgill, Michael D.

Bioorganic & Medicinal Chemistry, 07/2015, Vol.23(13), pp.3013-3032 [Periódico revisado por pares]

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Targeting conserved water molecules: Design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization

Davies , Nicholas G.M. ; Browne , Helen ; Davis , Ben ; Drysdale , Martin J. ; Foloppe , Nicolas ; Geoffrey , Stephanie ; Gibbons , Ben ; Hart , Terance ; Hubbard , Roderick ; Jensen , Michael Rugaard ; Mansell , Howard ; Massey , Andrew ; Matassova , Natalia ; Moore , Jonathan D. ; Murray , James ; Pratt , Robert ; Ray , Stuart ; Robertson , Alan ; Roughley , Stephen D. ; Schoepfer , Joseph ; Scriven , Kirsten ; Simmonite , Heather ; Stokes , Stephen ; Surgenor , Allan ; Webb , Paul ; Wood , Mike ; Wright , Lisa ; Brough , Paul

Bioorganic & medicinal chemistry, 2012, Vol.20(22), pp.6770-6789 [Periódico revisado por pares]

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6
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3,4-Dihydropyrimido(1,2- a)indol-10(2 H)-ones as potent non-peptidic inhibitors of caspase-3

Havran, Lisa M ; Chong, Dan C ; Childers, Wayne E ; Dollings, Paul J ; Dietrich, Arlene ; Harrison, Boyd L ; Marathias, Vasilios ; Tawa, Gregory ; Aulabaugh, Ann ; Cowling, Rebecca ; Kapoor, Bhupesh ; Xu, Weixin ; Mosyak, Lidia ; Moy, Franklin ; Hum, Wah-Tung ; Wood, Andrew ; Robichaud, Albert J

Bioorganic & Medicinal Chemistry, 2009, Vol.17(22), pp.7755-7768 [Periódico revisado por pares]

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7
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Synthesis, biological evaluation and molecular modelling of N-heterocyclic dipeptide aldehydes as selective calpain inhibitors

Jones, Matthew A ; Morton, James D ; Coxon, James M ; Mcnabb, Stephen B ; Lee, Hannah Y-Y ; Aitken, Steven G ; Mehrtens, Janna M ; Robertson, Lucinda J G ; Neffe, Axel T ; Miyamoto, Shigeru ; Bickerstaffe, Roy ; Gately, Karl ; Wood, Jacqueline M ; Abell, Andrew D

Bioorganic & medicinal chemistry, 15 July 2008, Vol.16(14), pp.6911-23 [Periódico revisado por pares]

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Deste Autor:

  1. Nathubhai, Amit
  2. Wood, Pauline J
  3. Lloyd, Matthew D
  4. Threadgill, Michael D
  5. Thompson, Andrew S

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