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Refinado por: Nome da Publicação: Bioorganic &Amp; Medicinal Chemistry Letters remover
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Identification and synthesis of potent and selective pyridyl-isoxazole based agonists of sphingosine-1-phosphate 1 (S1P1)

Guo, Junqing ; Watterson, Scott H ; Spergel, Steven H ; Kempson, James ; Langevine, Charles M ; Shen, Ding Ren ; Yarde, Melissa ; Cvijic, Mary Ellen ; Banas, Dana ; Liu, Richard ; Suchard, Suzanne J ; Gillooly, Kathleen ; Taylor, Tracy ; Rex-Rabe, Sandra ; Shuster, David J ; Mcintyre, Kim W ; Cornelius, Georgia ; D'Arienzo, Celia ; Marino

Bioorganic & medicinal chemistry letters, 15 May 2016, Vol.26(10), pp.2470-2474 [Periódico revisado por pares]

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Imidazo[4,5-d]thiazolo[5,4-b]pyridine based inhibitors of IKK2: Synthesis, SAR, PK/PD and activity in a preclinical model of rheumatoid arthritis

Dyckman, Alaric J ; Langevine, Charles M ; Quesnelle, Claude ; Kempson, James ; Guo, Junqing ; Gill, Patrice ; Spergel, Steven H ; Watterson, Scott H ; Li, Tianle ; Nirschl, David S ; Gillooly, Kathleen M ; Pattoli, Mark A ; Mcintyre, Kim W ; Chen, Laishun ; Mckinnon, Murray ; Dodd, John H ; Barrish, Joel C ; Burke, James R ; Pitts, William J

Bioorganic & Medicinal Chemistry Letters, 01 January 2011, Vol.21(1), pp.383-386 [Periódico revisado por pares]

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Novel tricyclic inhibitors of IKK2: discovery and SAR leading to the identification of 2-methoxy-N-((6-(1-methyl-4-(methylamino)-1,6-dihydroimidazo4,5-dpyrrolo2,3-bpyridin-7-yl)pyridin-2-yl)methyl)acetamide (BMS-066)

Watterson, Scott H ; Langevine, Charles M ; Van Kirk, Katy ; Kempson, James ; Guo, Junquing ; Spergel, Steven H ; Das, Jagabandhu ; Moquin, Robert V ; Dyckman, Alaric J ; Nirschl, David ; Gregor, Kurt ; Pattoli, Mark A ; Yang, Xiaoxia ; Mcintyre, Kim W ; Yang, Guchen ; Galella, Michael A ; Booth-Lute, Hollie ; Chen, Laishun ; Yang, Zheng ; Wang-Iverson

Bioorganic & medicinal chemistry letters, 01 December 2011, Vol.21(23), pp.7006-12 [Periódico revisado por pares]

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Discovery of pyrrolo1,2-bpyridazine-3-carboxamides as Janus kinase (JAK) inhibitors

Duan, James J-W ; Lu, Zhonghui ; Jiang, Bin ; Yang, Bingwei V ; Doweyko, Lidia M ; Nirschl, David S ; Haque, Lauren E ; Lin, Shuqun ; Brown, Gregory ; Hynes, John ; Tokarski, John S ; Sack, John S ; Khan, Javed ; Lippy, Jonathan S ; Zhang, Rosemary F ; Pitt, Sidney ; Shen, Guoxiang ; Pitts, William J ; Carter, Percy H ; Barrish

Bioorganic & medicinal chemistry letters, 15 December 2014, Vol.24(24), pp.5721-5726 [Periódico revisado por pares]

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Identification of potent pyrimidine inhibitors of phosphodiesterase 7 (PDE7) and their ability to inhibit T cell proliferation

Guo, Junqing ; Watson, Andrew ; Kempson, James ; Carlsen, Marianne ; Barbosa, Joseph ; Stebbins, Karen ; Lee, Deborah ; Dodd, John ; Nadler, Steven G ; Mckinnon, Murray ; Barrish, Joel ; Pitts, William J

Bioorganic & Medicinal Chemistry Letters, 2009, Vol.19(7), pp.1935-1938 [Periódico revisado por pares]

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Synthesis, initial SAR and biological evaluation of 1,6-dihydroimidazo[4,5- d]pyrrolo[2,3- b]pyridin-4-amine derived inhibitors of IκB kinase

Kempson, James ; Guo, Junqing ; Das, Jagabandhu ; Moquin, Robert V ; Spergel, Steven H ; Watterson, Scott H ; Langevine, Charles M ; Dyckman, Alaric J ; Pattoli, Mark ; Burke, James R ; Yang, Xiaoxia ; Gillooly, Kathleen M ; Mcintyre, Kim W ; Chen, Laishun ; Dodd, John H ; Mckinnon, Murray ; Barrish, Joel C ; Pitts, William J

Bioorganic & Medicinal Chemistry Letters, 2009, Vol.19(10), pp.2646-2649 [Periódico revisado por pares]

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Deste Autor:

  1. Barrish, Joel
  2. Mckinnon, Murray
  3. Pitts, William J.
  4. Kempson, James
  5. Barrish, Joel C

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