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Refinado por: assunto: Anatomy & Physiology remover Nome da Publicação: Bioorganic & medicinal chemistry letters remover
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The design and synthesis of novel, potent and orally bioavailable N-aryl piperazine-1-carboxamide CCR2 antagonists with very high hERG selectivity

Cumming, John G ; Bower, Justin F ; Waterson, David ; Faull, Alan ; Poyser, Philip J ; Turner, Paul ; Mcdermott, Benjamin ; Campbell, Andrew D ; Hudson, Julian ; James, Michael ; Winter, Jon ; Wood, Christine

Bioorganic & Medicinal Chemistry Letters, 15 June 2012, Vol.22(12), pp.3895-3899 [Periódico revisado por pares]

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Selective non zinc binding inhibitors of MMP13

Savi, Chris De ; Morley, Andrew D ; Ting, Attilla ; Nash, Ian ; Karabelas, Kostas ; Wood, Christine M ; James, Michael ; Norris, Stephen J ; Karoutchi, Galith ; Rankine, Neil ; Hamlin, Gordon ; Macfaul, Philip A ; Ryan, David ; Baker, Sarah V ; Hargreaves, David ; Gerhardt, Stefan

Bioorganic & Medicinal Chemistry Letters, 2011, Vol.21(14), pp.4215-4219 [Periódico revisado por pares]

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SAR and biological evaluation of 3-azabicyclo[3.1.0]hexane derivatives as μ opioid ligands

Lunn, Graham ; Roberts, Lee R ; Content, Stephane ; Critcher, Douglas J ; Douglas, Sara ; Fenwick, Ashley E ; Gethin, David M ; Goodwin, Graham ; Greenway, David ; Greenwood, Sean ; Hall, Kim ; Thomas, Martin ; Thompson, Stephen ; Williams, David ; Wood, Gavin ; Wylie, Andrew

Bioorganic & Medicinal Chemistry Letters, 15 March 2012, Vol.22(6), pp.2200-2203 [Periódico revisado por pares]

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Identification, optimisation and in vivo evaluation of oxadiazole DGAT-1 inhibitors for the treatment of obesity and diabetes

Mccoull, William ; Addie, Matthew S ; Birch, Alan M ; Birtles, Susan ; Buckett, Linda K ; Butlin, Roger J ; Bowker, Suzanne S ; Boyd, Scott ; Chapman, Stephen ; Davies, Robert D.M ; Donald, Craig S ; Green, Clive P ; Jenner, Chloe ; Kemmitt, Paul D ; Leach, Andrew G ; Moody, Graeme C ; Morentin Gutierrez, Pablo ; Newcombe, Nicholas J ; Nowak, Thorsten ; Packer, Martin J ; Plowright, Alleyn T ; Revill, John ; Schofield, Paul ; Sheldon, Chris ; Stokes, Steve ; Turnbull, Andrew V ; Wang, Steven J.Y ; Whalley, David P ; Matthew Wood, J

Bioorganic & Medicinal Chemistry Letters, 15 June 2012, Vol.22(12), pp.3873-3878 [Periódico revisado por pares]

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Discovery, optimisation and in vivo evaluation of novel GPR119 agonists

Brocklehurst, Katy J ; Broo, Anders ; Butlin, Roger J ; Brown, Hayley S ; Clarke, David S ; Davidsson, Öjvind ; Goldberg, Kristin ; Groombridge, Sam D ; Kelly, Elizabeth E ; Leach, Andrew ; Mckerrecher, Darren ; O’donnell, Charles ; Poucher, Simon ; Schofield, Paul ; Scott, James S ; Teague, Joanne ; Westgate, Leanne ; Wood, Matt J.M

Bioorganic & Medicinal Chemistry Letters, 2011, Vol.21(24), pp.7310-7316 [Periódico revisado por pares]

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Discovery of AZD3514, a small-molecule androgen receptor downregulator for treatment of advanced prostate cancer

Bradbury, Robert H ; Acton, David G ; Broadbent, Nicola L ; Brooks, A. Nigel ; Carr, Gregory R ; Hatter, Glenn ; Hayter, Barry R ; Hill, Kathryn J ; Howe, Nicholas J ; Jones, Rhys D.O ; Jude, David ; Lamont, Scott G ; Loddick, Sarah A ; Mcfarland, Heather L ; Parveen, Zaieda ; Rabow, Alfred A ; Sharma-Singh, Gorkhn ; Stratton, Natalie C ; Thomason, Andrew G ; Trueman, Dawn ; Walker, Graeme E ; Wells, Stuart L ; Wilson, Joanne ; Wood, J. Matthew

Bioorganic & Medicinal Chemistry Letters, 01 April 2013, Vol.23(7), pp.1945-1948 [Periódico revisado por pares]

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Development of a novel class of potent and selective FIXa inhibitors

Zhang, Ting ; Andre, Patrick ; Bateman, Thomas J ; Chen, Yi-Heng ; Desai, Kunal ; Ellsworth, Kenneth ; Geissler, Wayne M ; Guo, Liangqin ; Hruza, Alan ; Jian, Tianying ; Meng, Dongfang ; Parker, Dann L ; Qian, Xiaoxia ; Reichert, Paul ; Sherer, Edward C ; Shu, Min ; Smith, Cameron J ; Sonatore, Lisa M ; Tschirret-Guth, Richard ; Nolting, Andrew F ; Orr, Robert ; Campeau, Louis-Charles ; Araki, Kazuto ; Nishimura, Teruyuki ; Sakurada, Isao ; Wood, Harold B

Bioorganic & Medicinal Chemistry Letters, 01 November 2015, Vol.25(21), pp.4945-4949 [Periódico revisado por pares]

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The identification of a selective dopamine D 2 partial agonist, D 3 antagonist displaying high levels of brain exposure

Holmes, Ian P ; Blunt, Richard J ; Lorthioir, Olivier E ; Blowers, Stephen M ; Gribble, Andy ; Payne, Andrew H ; Stansfield, Ian G ; Wood, Martyn ; Woollard, Patrick M ; Reavill, Charlie ; Howes, Claire M ; Micheli, Fabrizio ; Fabio, Romano Di ; Donati, Daniele ; Terreni, Silvia ; Hamprecht, Dieter ; Arista, Luca ; Worby, Angela ; Watson, Steve P

Bioorganic & Medicinal Chemistry Letters, 2010, Vol.20(6), pp.2013-2016 [Periódico revisado por pares]

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9
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Novel mechanism of inhibiting beta-lactamases by sulfonylation using beta-sultams

Page, Michael I ; Hinchliffe, Paul S ; Wood, J Matthew ; Harding, Lindsay P ; Laws, Andrew P

Bioorganic & medicinal chemistry letters, 15 December 2003, Vol.13(24), pp.4489-92 [Periódico revisado por pares]

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10
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Dipeptidyl nitrile inhibitors of Cathepsin L

Asaad, Nabil ; Bethel, Paul A ; Coulson, Michelle D ; Dawson, Jack E ; Ford, Susannah J ; Gerhardt, Stefan ; Grist, Matthew ; Hamlin, Gordon A ; James, Michael J ; Jones, Emma V ; Karoutchi, Galith I ; Kenny, Peter W ; Morley, Andrew D ; Oldham, Keith ; Rankine, Neil ; Ryan, David ; Wells, Stuart L ; Wood, Linda ; Augustin, Martin ; Krapp, Stephan ; Simader, Hannes ; Steinbacher, Stefan

Bioorganic & Medicinal Chemistry Letters, 01 August 2009, Vol.19(15), pp.4280-4283 [Periódico revisado por pares]

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Deste Autor:

  1. James, Michael
  2. Luscombe, Vincent B
  3. Bubser, Michael
  4. Wood, Michael W
  5. Bollinger, Katrina A

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