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Inhibition of dengue viruses by N-methylcytisine thio derivatives through targeting viral envelope protein and NS2B-NS3 protease
Inhibition of dengue viruses by N-methylcytisine thio derivatives through targeting viral envelope protein and NS2B-NS3 protease
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Inhibition of dengue viruses by N-methylcytisine thio derivatives through targeting viral envelope protein and NS2B-NS3 protease

Lin, Chen-Sheng ; Lu, Chih-Hao ; Lin, Tsai-Hsiu ; Kiu, Yan-Tung ; Kan, Ju-Ying ; Chang, Yu-Jen ; Hung, Ping-Yi ; Koval'skaya, Alena V. ; Tsypyshev, Dmitry O. ; Tsypysheva, Inna P. ; Lin, Cheng-Wen

Bioorganic & medicinal chemistry letters, 2024-02, Vol.99, p.129623-129623, Article 129623 [Periódico revisado por pares]

England: Elsevier Ltd

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2
Exploring small molecules with pan-genotypic inhibitory activities against hepatitis C virus NS3/4A serine protease
Exploring small molecules with pan-genotypic inhibitory activities against hepatitis C virus NS3/4A serine protease
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Exploring small molecules with pan-genotypic inhibitory activities against hepatitis C virus NS3/4A serine protease

Ren, Jinhong ; Ojeda, Isabel ; Patel, Maulik ; Johnson, Michael E. ; Lee, Hyun

Bioorganic & medicinal chemistry letters, 2019-08, Vol.29 (16), p.2349-2353 [Periódico revisado por pares]

England: Elsevier Ltd

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3
Novel fullerene derivatives as dual inhibitors of Hepatitis C virus NS5B polymerase and NS3/4A protease
Novel fullerene derivatives as dual inhibitors of Hepatitis C virus NS5B polymerase and NS3/4A protease
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Novel fullerene derivatives as dual inhibitors of Hepatitis C virus NS5B polymerase and NS3/4A protease

Kataoka, Hiroki ; Ohe, Tomoyuki ; Takahashi, Kyoko ; Nakamura, Shigeo ; Mashino, Tadahiko

Bioorganic & medicinal chemistry letters, 2016-10, Vol.26 (19), p.4565-4567 [Periódico revisado por pares]

England: Elsevier Ltd

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4
Structure-based design of a novel series of azetidine inhibitors of the hepatitis C virus NS3/4A serine protease
Structure-based design of a novel series of azetidine inhibitors of the hepatitis C virus NS3/4A serine protease
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Structure-based design of a novel series of azetidine inhibitors of the hepatitis C virus NS3/4A serine protease

Parsy, Christophe ; Alexandre, François-René ; Brandt, Guillaume ; Caillet, Catherine ; Cappelle, Sylvie ; Chaves, Dominique ; Convard, Thierry ; Derock, Michel ; Gloux, Damien ; Griffon, Yann ; Lallos, Lisa ; Leroy, Frédéric ; Liuzzi, Michel ; Loi, Anna-Giulia ; Moulat, Laure ; Musiu, Chiara ; Rahali, Houcine ; Roques, Virginie ; Seifer, Maria ; Standring, David ; Surleraux, Dominique

Bioorganic & medicinal chemistry letters, 2014-09, Vol.24 (18), p.4444-4449 [Periódico revisado por pares]

England: Elsevier Ltd

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5
QSAR studies of the bioactivity of hepatitis C virus (HCV) NS3/4A protease inhibitors by multiple linear regression (MLR) and support vector machine (SVM)
QSAR studies of the bioactivity of hepatitis C virus (HCV) NS3/4A protease inhibitors by multiple linear regression (MLR) and support vector machine (SVM)
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QSAR studies of the bioactivity of hepatitis C virus (HCV) NS3/4A protease inhibitors by multiple linear regression (MLR) and support vector machine (SVM)

Qin, Zijian ; Wang, Maolin ; Yan, Aixia

Bioorganic & medicinal chemistry letters, 2017-07, Vol.27 (13), p.2931-2938 [Periódico revisado por pares]

England: Elsevier Ltd

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6
P3-P4 ureas and reverse carbamates as potent HCV NS3 protease inhibitors: Effective transposition of the P4 hydrogen bond donor
P3-P4 ureas and reverse carbamates as potent HCV NS3 protease inhibitors: Effective transposition of the P4 hydrogen bond donor
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P3-P4 ureas and reverse carbamates as potent HCV NS3 protease inhibitors: Effective transposition of the P4 hydrogen bond donor

Venables, Brian L. ; Sin, Ny ; Wang, Alan Xiangdong ; Sun, Li-Qiang ; Tu, Yong ; Hernandez, Dennis ; Sheaffer, Amy ; Lee, Min ; Dunaj, Cindy ; Zhai, Guangzhi ; Barry, Diana ; Friborg, Jacques ; Yu, Fei ; Knipe, Jay ; Sandquist, Jason ; Falk, Paul ; Parker, Dawn ; Good, Andrew C. ; Rajamani, Ramkumar ; McPhee, Fiona ; Meanwell, Nicholas A. ; Scola, Paul M.

Bioorganic & medicinal chemistry letters, 2018-06, Vol.28 (10), p.1853-1859 [Periódico revisado por pares]

England: Elsevier Ltd

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7
Inhibitory activity of cyclohexenyl chalcone derivatives and flavonoids of fingerroot, Boesenbergia rotunda (L.), towards dengue-2 virus NS3 protease
Inhibitory activity of cyclohexenyl chalcone derivatives and flavonoids of fingerroot, Boesenbergia rotunda (L.), towards dengue-2 virus NS3 protease
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Inhibitory activity of cyclohexenyl chalcone derivatives and flavonoids of fingerroot, Boesenbergia rotunda (L.), towards dengue-2 virus NS3 protease

Kiat, Tan Siew ; Pippen, Richard ; Yusof, Rohana ; Ibrahim, Halijah ; Khalid, Norzulaani ; Rahman, Noorsaadah Abd

Bioorganic & medicinal chemistry letters, 2006-06, Vol.16 (12), p.3337-3340 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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8
Structure–activity relationship study on a novel series of cyclopentane-containing macrocyclic inhibitors of the hepatitis C virus NS3/4A protease leading to the discovery of TMC435350
Structure–activity relationship study on a novel series of cyclopentane-containing macrocyclic inhibitors of the hepatitis C virus NS3/4A protease leading to the discovery of TMC435350
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Structure–activity relationship study on a novel series of cyclopentane-containing macrocyclic inhibitors of the hepatitis C virus NS3/4A protease leading to the discovery of TMC435350

Raboisson, Pierre ; de Kock, Herman ; Rosenquist, Åsa ; Nilsson, Magnus ; Salvador-Oden, Lourdes ; Lin, Tse-I ; Roue, Natalie ; Ivanov, Vladimir ; Wähling, Horst ; Wickström, Kristina ; Hamelink, Elizabeth ; Edlund, Michael ; Vrang, Lotta ; Vendeville, Sandrine ; Van de Vreken, Wim ; McGowan, David ; Tahri, Abdellah ; Hu, Lili ; Boutton, Carlo ; Lenz, Oliver ; Delouvroy, Frederic ; Pille, Geert ; Surleraux, Dominique ; Wigerinck, Piet ; Samuelsson, Bertil ; Simmen, Kenneth

Bioorganic & medicinal chemistry, 2008-09, Vol.18 (17), p.4853-4858 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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9
Discovery and structural diversity of the hepatitis C virus NS3/4A serine protease inhibitor series leading to clinical candidate IDX320
Discovery and structural diversity of the hepatitis C virus NS3/4A serine protease inhibitor series leading to clinical candidate IDX320
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Discovery and structural diversity of the hepatitis C virus NS3/4A serine protease inhibitor series leading to clinical candidate IDX320

Parsy, Christophe C. ; Alexandre, François-René ; Bidau, Valérie ; Bonnaterre, Florence ; Brandt, Guillaume ; Caillet, Catherine ; Cappelle, Sylvie ; Chaves, Dominique ; Convard, Thierry ; Derock, Michel ; Gloux, Damien ; Griffon, Yann ; Lallos, Lisa B. ; Leroy, Frederic ; Liuzzi, Michel ; Loi, Anna-Giulia ; Moulat, Laure ; Chiara, Musiu ; Rahali, Houcine ; Roques, Virginie ; Rosinovsky, Elodie ; Savin, Simon ; Seifer, Maria ; Standring, David ; Surleraux, Dominique

Bioorganic & medicinal chemistry letters, 2015-11, Vol.25 (22), p.5427-5436 [Periódico revisado por pares]

England: Elsevier Ltd

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10
The discovery and optimization of naphthalene-linked P2-P4 Macrocycles as inhibitors of HCV NS3 protease
The discovery and optimization of naphthalene-linked P2-P4 Macrocycles as inhibitors of HCV NS3 protease
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The discovery and optimization of naphthalene-linked P2-P4 Macrocycles as inhibitors of HCV NS3 protease

Bowsher, Michael ; Hiebert, Sheldon ; Li, Rongti ; Wang, Alan X. ; Friborg, Jacques ; Yu, Fei ; Hernandez, Dennis ; Wang, Ying-Kai ; Klei, Herbert ; Rajamani, Ramkumar ; Mosure, Kathy ; Knipe, Jay O. ; Meanwell, Nicholas A. ; McPhee, Fiona ; Scola, Paul M.

Bioorganic & medicinal chemistry letters, 2018-01, Vol.28 (1), p.43-48 [Periódico revisado por pares]

England: Elsevier Ltd

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