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Glucocorticoids target suppressor of cytokine signaling 1 (SOCS1) and type 1 interferons to regulate Toll-like receptor-induced STAT1 activation
Glucocorticoids target suppressor of cytokine signaling 1 (SOCS1) and type 1 interferons to regulate Toll-like receptor-induced STAT1 activation
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Glucocorticoids target suppressor of cytokine signaling 1 (SOCS1) and type 1 interferons to regulate Toll-like receptor-induced STAT1 activation

Bhattacharyya, Sandip ; Zhao, Yuxing ; Kay, Thomas W.H ; Muglia, Louis J

Proceedings of the National Academy of Sciences - PNAS, 2011-06, Vol.108 (23), p.9554-9559 [Periódico revisado por pares]

United States: National Academy of Sciences

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2
Deficiency in Type I Interferon Signaling Prevents the Early Interferon-Induced Gene Signature in Pancreatic Islets but Not Type 1 Diabetes in NOD Mice
Deficiency in Type I Interferon Signaling Prevents the Early Interferon-Induced Gene Signature in Pancreatic Islets but Not Type 1 Diabetes in NOD Mice
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Deficiency in Type I Interferon Signaling Prevents the Early Interferon-Induced Gene Signature in Pancreatic Islets but Not Type 1 Diabetes in NOD Mice

HONG SHENG QUAH ; MIRANDA-HERNANDEZ, Socorro ; GRAHAM, Kate L ; KHOO, Aimee ; HARDING, Ashley ; FYNCH, Stacey ; ELKERBOUT, Lorraine ; BRODNICKI, Thomas C ; BAXTER, Alan G ; KAY, Thomas W. H ; THOMAS, Helen E

Diabetes (New York, N.Y.), 2014-03, Vol.63 (3), p.1032-1040 [Periódico revisado por pares]

Alexandria, VA: American Diabetes Association

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3
Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients
Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients
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Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients

Coppieters, Ken T ; Dotta, Francesco ; Amirian, Natalie ; Campbell, Peter D ; Kay, Thomas W H ; Atkinson, Mark A ; Roep, Bart O ; von Herrath, Matthias G

The Journal of experimental medicine, 2012-01, Vol.209 (1), p.51-60 [Periódico revisado por pares]

United States: The Rockefeller University Press

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4
BIM Deficiency Protects NOD Mice From Diabetes by Diverting Thymocytes to Regulatory T Cells
BIM Deficiency Protects NOD Mice From Diabetes by Diverting Thymocytes to Regulatory T Cells
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BIM Deficiency Protects NOD Mice From Diabetes by Diverting Thymocytes to Regulatory T Cells

Krishnamurthy, Balasubramanian ; Chee, Jonathan ; Jhala, Gaurang ; Trivedi, Prerak ; Catterall, Tara ; Selck, Claudia ; Gurzov, Esteban N ; Brodnicki, Thomas C ; Graham, Kate L ; Wali, Jibran A ; Zhan, Yifan ; Gray, Daniel ; Strasser, Andreas ; Allison, Janette ; Thomas, Helen E ; Kay, Thomas W H

Diabetes (New York, N.Y.), 2015-09, Vol.64 (9), p.3229-3238 [Periódico revisado por pares]

United States: American Diabetes Association

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5
Proinsulin-specific, HLA-DQ8, and HLA-DQ8-transdimer-restricted CD4+ T cells infiltrate islets in type 1 diabetes
Proinsulin-specific, HLA-DQ8, and HLA-DQ8-transdimer-restricted CD4+ T cells infiltrate islets in type 1 diabetes
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Proinsulin-specific, HLA-DQ8, and HLA-DQ8-transdimer-restricted CD4+ T cells infiltrate islets in type 1 diabetes

Pathiraja, Vimukthi ; Kuehlich, Janine P ; Campbell, Peter D ; Krishnamurthy, Balasubramanian ; Loudovaris, Thomas ; Coates, P Toby H ; Brodnicki, Thomas C ; O'Connell, Philip J ; Kedzierska, Katherine ; Rodda, Christine ; Bergman, Philip ; Hill, Erin ; Purcell, Anthony W ; Dudek, Nadine L ; Thomas, Helen E ; Kay, Thomas W H ; Mannering, Stuart I

Diabetes (New York, N.Y.), 2015-01, Vol.64 (1), p.172-182 [Periódico revisado por pares]

United States: American Diabetes Association

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6
Interleukin-1β Produced in Response to Islet Autoantigen Presentation Differentiates T-Helper 17 Cells at the Expense of Regulatory T-Cells: Implications for the Timing of Tolerizing Immunotherapy
Interleukin-1β Produced in Response to Islet Autoantigen Presentation Differentiates T-Helper 17 Cells at the Expense of Regulatory T-Cells: Implications for the Timing of Tolerizing Immunotherapy
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Interleukin-1β Produced in Response to Islet Autoantigen Presentation Differentiates T-Helper 17 Cells at the Expense of Regulatory T-Cells: Implications for the Timing of Tolerizing Immunotherapy

BERTIN-MAGHIT, Sebastien ; DIMENG PANG ; THOMAS, Ranjeny ; O'SULLIVAN, Brendan ; BEST, Shannon ; DUGGAN, Emily ; PAUL, Sanjoy ; THOMAS, Helen ; KAY, Thomas W. H ; HARRISON, Leonard C ; STEPTOE, Raymond

Diabetes (New York, N.Y.), 2011-01, Vol.60 (1), p.248-257 [Periódico revisado por pares]

Alexandria, VA: American Diabetes Association

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7
T-Cell-Specific PTPN2 Deficiency in NOD Mice Accelerates the Development of Type 1 Diabetes and Autoimmune Comorbidities
T-Cell-Specific PTPN2 Deficiency in NOD Mice Accelerates the Development of Type 1 Diabetes and Autoimmune Comorbidities
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T-Cell-Specific PTPN2 Deficiency in NOD Mice Accelerates the Development of Type 1 Diabetes and Autoimmune Comorbidities

Wiede, Florian ; Brodnicki, Thomas C ; Goh, Pei Kee ; Leong, Yew A ; Jones, Gareth W ; Yu, Di ; Baxter, Alan G ; Jones, Simon A ; Kay, Thomas W H ; Tiganis, Tony

Diabetes (New York, N.Y.), 2019-06, Vol.68 (6), p.1251-1266 [Periódico revisado por pares]

United States: American Diabetes Association

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8
Baricitinib and β-Cell Function in Patients with New-Onset Type 1 Diabetes
Baricitinib and β-Cell Function in Patients with New-Onset Type 1 Diabetes
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Baricitinib and β-Cell Function in Patients with New-Onset Type 1 Diabetes

Waibel, Michaela ; Wentworth, John M ; So, Michelle ; Couper, Jennifer J ; Cameron, Fergus J ; MacIsaac, Richard J ; Atlas, Gabby ; Gorelik, Alexandra ; Litwak, Sara ; Sanz-Villanueva, Laura ; Trivedi, Prerak ; Ahmed, Simi ; Martin, Francis J ; Doyle, Madeleine E ; Harbison, Jessica E ; Hall, Candice ; Krishnamurthy, Balasubramanian ; Colman, Peter G ; Harrison, Leonard C ; Thomas, Helen E ; Kay, Thomas W H

The New England journal of medicine, 2023-12, Vol.389 (23), p.2140-2150 [Periódico revisado por pares]

United States: Massachusetts Medical Society

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9
Prevention of Humanized Diabetogenic CD8 T-Cell Responses in HLA-Transgenic NOD Mice by a Multipeptide Coupled-Cell Approach
Prevention of Humanized Diabetogenic CD8 T-Cell Responses in HLA-Transgenic NOD Mice by a Multipeptide Coupled-Cell Approach
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Prevention of Humanized Diabetogenic CD8 T-Cell Responses in HLA-Transgenic NOD Mice by a Multipeptide Coupled-Cell Approach

NIENS, Marijke ; GRIER, Alexandra E ; MARRON, Michele ; KAY, Thomas W. H ; GREINER, Dale L ; SERREZE, David V

Diabetes (New York, N.Y.), 2011-04, Vol.60 (4), p.1229-1236 [Periódico revisado por pares]

Alexandria, VA: American Diabetes Association

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10
Glucose Induces Pancreatic Islet Cell Apoptosis That Requires the BH3-Only Proteins Bim and Puma and Multi-BH Domain Protein Bax
Glucose Induces Pancreatic Islet Cell Apoptosis That Requires the BH3-Only Proteins Bim and Puma and Multi-BH Domain Protein Bax
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Glucose Induces Pancreatic Islet Cell Apoptosis That Requires the BH3-Only Proteins Bim and Puma and Multi-BH Domain Protein Bax

MCKENZIE, Mark D ; JAMIESON, Emma ; JANSEN, Elisa S ; SCOTT, Clare L ; HUANG, David C. S ; BOUILLET, Philippe ; ALLISON, Janette ; KAY, Thomas W. H ; STRASSER, Andreas ; THOMAS, Helen E

Diabetes (New York, N.Y.), 2010-03, Vol.59 (3), p.644-652 [Periódico revisado por pares]

Alexandria, VA: American Diabetes Association

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