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SAR inspired by aldehyde oxidase (AO) metabolism: Discovery of novel, CNS penetrant tricyclic M4 PAMs
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SAR inspired by aldehyde oxidase (AO) metabolism: Discovery of novel, CNS penetrant tricyclic M4 PAMs

Chopko, Trevor C. ; Han, Changho ; Gregro, Alison R. ; Engers, Darren W. ; Felts, Andrew S. ; Poslusney, Mike S. ; Bollinger, Katrina A. ; Morrison, Ryan D. ; Bubser, Michael ; Lamsal, Atin ; Luscombe, Vincent B. ; Cho, Hyekyung P. ; Schnetz-Boutaud, Nathalie C. ; Rodriguez, Alice L. ; Chang, Sichen ; Daniels, J. Scott ; Stec, Donald F. ; Niswender, Colleen M. ; Jones, Carrie K. ; Wood

Bioorganic & Medicinal Chemistry Letters, 08/2019, Vol.29(16), pp.2224-2228 [Periódico revisado por pares]

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VU6005806/AZN-00016130, an advanced M positive allosteric modulator (PAM) profiled as a potential preclinical development candidate

Engers, Darren W ; Melancon, Bruce J ; Gregro, Allison R ; Bertron, Jeanette L ; Bollinger, Sean R ; Felts, Andrew S ; Konkol, Leah C ; Wood, Michael R ; Bollinger, Katrina A ; Luscombe, Vincent B ; Rodriguez, Alice L ; Jones, Carrie K ; Bubser, Michael ; Yohn, Samantha E ; Wood, Michael W ; Brandon, Nicholas J ; Dugan, Mark E ; Niswender, Colleen M ; Jeffrey Conn, P ; Bridges

Bioorganic & medicinal chemistry letters, 16 May 2019 [Periódico revisado por pares]

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3
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Neural activity and emotional processing following military deployment: Effects of mild traumatic brain injury and posttraumatic stress disorder

Zuj, Daniel V ; Felmingham, Kim L ; Palmer, Matthew A ; Lawrence-Wood, Ellie ; Van Hooff, Miranda ; Lawrence, Andrew J ; Bryant, Richard A ; Mcfarlane, Alexander C

Brain and cognition, November 2017, Vol.118, pp.19-26 [Periódico revisado por pares]

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4
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Establishing the role of rare coding variants in known Parkinson's disease risk loci

Jansen, Iris E ; Gibbs, J. Raphael ; Nalls, Mike A ; Price, T. Ryan ; Lubbe, Steven ; van Rooij, Jeroen ; Uitterlinden, André G ; Kraaij, Robert ; Williams, Nigel M ; Brice, Alexis ; Hardy, John ; Wood, Nicholas W ; Morris, Huw R ; Gasser, Thomas ; Singleton, Andrew B ; Heutink, Peter ; Sharma, Manu International Parkinson'S Disease Genomics Consortium (Corporate Author)

Neurobiology of Aging, November 2017, Vol.59, pp.220.e11-220.e18 [Periódico revisado por pares]

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5
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NeuroChip, an updated version of the NeuroX genotyping platform to rapidly screen for variants associated with neurological diseases

Blauwendraat, Cornelis ; Faghri, Faraz ; Pihlstrom, Lasse ; Geiger, Joshua T ; Elbaz, Alexis ; Lesage, Suzanne ; Corvol, Jean-Christophe ; May, Patrick ; Nicolas, Aude ; Abramzon, Yevgeniya ; Murphy, Natalie A ; Gibbs, J Raphael ; Ryten, Mina ; Ferrari, Raffaele ; Bras, Jose ; Guerreiro, Rita ; Williams, Julie ; Sims, Rebecca ; Lubbe, Steven ; Hernandez

Neurobiology of aging, September 2017, Vol.57, pp.247.e9-247.e13 [Periódico revisado por pares]

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6
Influence of product placement in children's movies on children's snack choices
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Influence of product placement in children's movies on children's snack choices

Brown, Callie L. ; Matherne, Camden E. ; Bulik, Cynthia M. ; Howard, Janna B. ; Ravanbakht, Sophie N. ; Skinner, Asheley C. ; Wood, Charles T. ; Bardone-Cone, Anna M. ; Brown, Jane D. ; Perrin, Andrew J. ; Levine, Cary ; Steiner, Michael J. ; Perrin, Eliana M.

Appetite, 07/2017, Vol.114, C, pp.118-124 [Periódico revisado por pares]

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7
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Enhancer deletion generates cellular phenotypic diversity due to bimodal gene expression

De Gobbi, Marco ; Brazel, Ailbhe J ; Sharpe, Jacqueline A ; Sloane-Stanley, Jacqueline A ; Smith, Andrew J ; Wood, William G ; Vernimmen, Douglas

Blood Cells, Molecules and Diseases, May 2017, Vol.64, pp.10-12 [Periódico revisado por pares]

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8
Identification of dual PPARα/γ agonists and their effects on lipid metabolism
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Identification of dual PPARα/γ agonists and their effects on lipid metabolism

Gao, Quanqing ; Hanh, Jacky ; Váradi, Linda ; Cairns, Rose ; Sjöström, Helena ; Liao, Vivian W.Y. ; Wood, Peta ; Balaban, Seher ; Ong, Jennifer Ai ; Lin, Hsuan-Yu Jennifer ; Lai, Felcia ; Hoy, Andrew J. ; Grewal, Thomas ; Groundwater, Paul W. ; Hibbs, David E.

Bioorganic & Medicinal Chemistry, 12/2015, Vol.23(24), pp.7676-7684 [Periódico revisado por pares]

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9
Development of a novel class of potent and selective FIXa inhibitors
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Development of a novel class of potent and selective FIXa inhibitors

Zhang, Ting ; Andre, Patrick ; Bateman, Thomas J. ; Chen, Yi-Heng ; Desai, Kunal ; Ellsworth, Kenneth ; Geissler, Wayne M. ; Guo, Liangqin ; Hruza, Alan ; Jian, Tianying ; Meng, Dongfang ; Parker, Dann L. ; Qian, Xiaoxia ; Reichert, Paul ; Sherer, Edward C. ; Shu, Min ; Smith, Cameron J. ; Sonatore, Lisa M. ; Tschirret-Guth, Richard ; Nolting, Andrew F. ; Orr, Robert ; Campeau, Louis-Charles ; Araki, Kazuto ; Nishimura, Teruyuki ; Sakurada, Isao ; Wood, Harold B.

Bioorganic & Medicinal Chemistry Letters, 11/2015, Vol.25(21), pp.4945-4949 [Periódico revisado por pares]

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Exploration of the nicotinamide-binding site of the tankyrases, identifying 3-arylisoquinolin-1-ones as potent and selective inhibitors in vitro
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Exploration of the nicotinamide-binding site of the tankyrases, identifying 3-arylisoquinolin-1-ones as potent and selective inhibitors in vitro

Paine, Helen A. ; Nathubhai, Amit ; Woon, Esther C.Y. ; Sunderland, Peter T. ; Wood, Pauline J. ; Mahon, Mary F. ; Lloyd, Matthew D. ; Thompson, Andrew S. ; Haikarainen, Teemu ; Narwal, Mohit ; Lehtiö, Lari ; Threadgill, Michael D.

Bioorganic & Medicinal Chemistry, 09/2015, Vol.23(17), pp.5891-5908 [Periódico revisado por pares]

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Deste Autor:

  1. Wood, Nicholas W.
  2. Hardy, John
  3. Gasser, Thomas
  4. Nathubhai, Amit
  5. Brice, Alexis

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