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Racemases and epimerases operating through a 1,1-proton transfer mechanism: reactivity, mechanism and inhibition
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Racemases and epimerases operating through a 1,1-proton transfer mechanism: reactivity, mechanism and inhibition

Lloyd, Matthew D ; Yevglevskis, Maksims ; Nathubhai, Amit ; James, Tony D ; Threadgill, Michael D ; Woodman, Timothy J

Chemical Society reviews, 2021-05, Vol.5 (1), p.5952-5984 [Periódico revisado por pares]

London: Royal Society of Chemistry

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2
A novel colorimetric assay for α-methylacyl-CoA racemase 1A (AMACR; P504S) utilizing the elimination of 2,4-dinitrophenolate
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A novel colorimetric assay for α-methylacyl-CoA racemase 1A (AMACR; P504S) utilizing the elimination of 2,4-dinitrophenolate

Yevglevskis, Maksims ; Lee, Guat L ; Nathubhai, Amit ; Petrova, Yoana D ; James, Tony D ; Threadgill, Michael D ; Woodman, Timothy J ; Lloyd, Matthew D

Chemical communications (Cambridge, England), 2017-05, Vol.53 (37), p.5087-5090 [Periódico revisado por pares]

England

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3
A novel colorimetric assay for α-methylacyl-CoA racemase 1A (AMACR; P504S) utilizing the elimination of 2,4-dinitrophenolateElectronic supplementary information (ESI) available: Experimental details including synthesis of compounds, kinetic plots, inhibitor testing. See DOI: 10.1039/c7cc00476a
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Artigo
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A novel colorimetric assay for α-methylacyl-CoA racemase 1A (AMACR; P504S) utilizing the elimination of 2,4-dinitrophenolateElectronic supplementary information (ESI) available: Experimental details including synthesis of compounds, kinetic plots, inhibitor testing. See DOI: 10.1039/c7cc00476a

Yevglevskis, Maksims ; Lee, Guat L ; Nathubhai, Amit ; Petrova, Yoana D ; James, Tony D ; Threadgill, Michael D ; Woodman, Timothy J ; Lloyd, Matthew D

2017-05

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4
Identification of novel small-molecule inhibitors of α-methylacyl-CoA racemase (AMACR; P504S) and structure-activity relationships
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Identification of novel small-molecule inhibitors of α-methylacyl-CoA racemase (AMACR; P504S) and structure-activity relationships

Petrova, Yoana D. ; Wadda, Katty ; Nathubhai, Amit ; Yevglevskis, Maksims ; Mitchell, Paul J. ; James, Tony D. ; Threadgill, Michael D. ; Woodman, Timothy J. ; Lloyd, Matthew D.

Bioorganic chemistry, 2019-11, Vol.92, p.103264, Article 103264 [Periódico revisado por pares]

United States: Elsevier Inc

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5
Novel 2-arylthiopropanoyl-CoA inhibitors of α-methylacyl-CoA racemase 1A (AMACR; P504S) as potential anti-prostate cancer agents
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Novel 2-arylthiopropanoyl-CoA inhibitors of α-methylacyl-CoA racemase 1A (AMACR; P504S) as potential anti-prostate cancer agents

Yevglevskis, Maksims ; Nathubhai, Amit ; Wadda, Katty ; Lee, Guat L. ; Al-Rawi, Suzanne ; Jiao, Tingying ; Mitchell, Paul J. ; James, Tony D. ; Threadgill, Michael D. ; Woodman, Timothy J. ; Lloyd, Matthew D.

Bioorganic chemistry, 2019-11, Vol.92, p.103263, Article 103263 [Periódico revisado por pares]

United States: Elsevier Inc

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6
Structure-activity relationships of rationally designed AMACR 1A inhibitors
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Structure-activity relationships of rationally designed AMACR 1A inhibitors

Yevglevskis, Maksims ; Lee, Guat L. ; Nathubhai, Amit ; Petrova, Yoana D. ; James, Tony D. ; Threadgill, Michael D. ; Woodman, Timothy J. ; Lloyd, Matthew D.

Bioorganic chemistry, 2018-09, Vol.79, p.145-154 [Periódico revisado por pares]

United States: Elsevier Inc

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