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Attenuation of the Aggregation and Neurotoxicity of Amyloid-β Peptides by Catalytic Photooxygenation
Attenuation of the Aggregation and Neurotoxicity of Amyloid-β Peptides by Catalytic Photooxygenation
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Attenuation of the Aggregation and Neurotoxicity of Amyloid-β Peptides by Catalytic Photooxygenation

Taniguchi, Atsuhiko ; Sasaki, Daisuke ; Shiohara, Azusa ; Iwatsubo, Takeshi ; Tomita, Taisuke ; Sohma, Youhei ; Kanai, Motomu

Angewandte Chemie (International ed.), 2014-01, Vol.53 (5), p.1382-1385 [Periódico revisado por pares]

Weinheim: WILEY-VCH Verlag

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2
Covalent modifier-type aggregation inhibitor of amyloid-β based on a cyclo-KLVFF motif
Covalent modifier-type aggregation inhibitor of amyloid-β based on a cyclo-KLVFF motif
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Covalent modifier-type aggregation inhibitor of amyloid-β based on a cyclo-KLVFF motif

Kino, Ryuto ; Araya, Takushi ; Arai, Tadamasa ; Sohma, Youhei ; Kanai, Motomu

Bioorganic & medicinal chemistry letters, 2015-08, Vol.25 (15), p.2972-2975 [Periódico revisado por pares]

England: Elsevier Ltd

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3
A Cyclic KLVFF-Derived Peptide Aggregation Inhibitor Induces the Formation of Less-Toxic Off-Pathway Amyloid-β Oligomers
A Cyclic KLVFF-Derived Peptide Aggregation Inhibitor Induces the Formation of Less-Toxic Off-Pathway Amyloid-β Oligomers
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A Cyclic KLVFF-Derived Peptide Aggregation Inhibitor Induces the Formation of Less-Toxic Off-Pathway Amyloid-β Oligomers

Arai, Tadamasa ; Sasaki, Daisuke ; Araya, Takushi ; Sato, Takeshi ; Sohma, Youhei ; Kanai, Motomu

Chembiochem : a European journal of chemical biology, 2014-11, Vol.15 (17), p.2577-2583 [Periódico revisado por pares]

Weinheim: WILEY-VCH Verlag

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4
O-Acyl isopeptide method: development of an O-acyl isodipeptide unit for Boc SPPS and its application to the synthesis of A[beta]1-42 isopeptide
O-Acyl isopeptide method: development of an O-acyl isodipeptide unit for Boc SPPS and its application to the synthesis of A[beta]1-42 isopeptide
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O-Acyl isopeptide method: development of an O-acyl isodipeptide unit for Boc SPPS and its application to the synthesis of A[beta]1-42 isopeptide

Yoshiya, Taku ; Uemura, Tsuyoshi ; Maruno, Takahiro ; Kubo, Shigeru ; Kiso, Yoshiaki ; Sohma, Youhei ; Kobayashi, Yuji ; Yoshizawa-Kumagaye, Kumiko ; Nishiuchi, Yuji

Journal of peptide science, 2014-09, Vol.20 (9), p.669-674 [Periódico revisado por pares]

Bognor Regis: Wiley Subscription Services, Inc

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5
Synthesis of chemically-tethered amyloid-β segment trimer possessing amyloidogenic properties
Synthesis of chemically-tethered amyloid-β segment trimer possessing amyloidogenic properties
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Synthesis of chemically-tethered amyloid-β segment trimer possessing amyloidogenic properties

Shinoda, Kiyomichi ; Sohma, Youhei ; Kanai, Motomu

Bioorganic & medicinal chemistry letters, 2015-08, Vol.25 (15), p.2976-2979 [Periódico revisado por pares]

England: Elsevier Ltd

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6
“Click Peptides”--Chemical Biology-Oriented Synthesis of Alzheimer's Disease-Related Amyloid β Peptide (Aβ) Analogues Based on the “O-Acyl Isopeptide Method”
“Click Peptides”--Chemical Biology-Oriented Synthesis of Alzheimer's Disease-Related Amyloid β Peptide (Aβ) Analogues Based on the “O-Acyl Isopeptide Method”
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“Click Peptides”--Chemical Biology-Oriented Synthesis of Alzheimer's Disease-Related Amyloid β Peptide (Aβ) Analogues Based on the “O-Acyl Isopeptide Method”

Sohma, Youhei ; Kiso, Yoshiaki

Chembiochem : a European journal of chemical biology, 2006-10, Vol.7 (10), p.1549-1557 [Periódico revisado por pares]

Weinheim: Wiley-VCH Verlag

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7
A new class of aggregation inhibitor of amyloid-β peptide based on an O-acyl isopeptide
A new class of aggregation inhibitor of amyloid-β peptide based on an O-acyl isopeptide
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A new class of aggregation inhibitor of amyloid-β peptide based on an O-acyl isopeptide

Kawashima, Hiroyuki ; Sohma, Youhei ; Nakanishi, Tomoya ; Kitamura, Hitomi ; Mukai, Hidehito ; Yamashita, Masayuki ; Akaji, Kenichi ; Kiso, Yoshiaki

Bioorganic & medicinal chemistry, 2013-11, Vol.21 (21), p.6323-6327 [Periódico revisado por pares]

England: Elsevier Ltd

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8
Rational Design and Identification of a Non-Peptidic Aggregation Inhibitor of Amyloid-β Based on a Pharmacophore Motif Obtained from cyclo[-Lys-Leu-Val-Phe-Phe-]
Rational Design and Identification of a Non-Peptidic Aggregation Inhibitor of Amyloid-β Based on a Pharmacophore Motif Obtained from cyclo[-Lys-Leu-Val-Phe-Phe-]
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Rational Design and Identification of a Non-Peptidic Aggregation Inhibitor of Amyloid-β Based on a Pharmacophore Motif Obtained from cyclo[-Lys-Leu-Val-Phe-Phe-]

Arai, Tadamasa ; Araya, Takushi ; Sasaki, Daisuke ; Taniguchi, Atsuhiko ; Sato, Takeshi ; Sohma, Youhei ; Kanai, Motomu

Angewandte Chemie (International ed.), 2014-07, Vol.53 (31), p.8236-8239 [Periódico revisado por pares]

Weinheim: WILEY-VCH Verlag

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9
Development of O-acyl isopeptide method
Development of O-acyl isopeptide method
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Development of O-acyl isopeptide method

Sohma, Youhei ; Yoshiya, Taku ; Taniguchi, Atsuhiko ; Kimura, Tooru ; Hayashi, Yoshio ; Kiso, Yoshiaki

Biopolymers, 2007, Vol.88 (2), p.253-262 [Periódico revisado por pares]

Hoboken: Wiley Subscription Services, Inc., A Wiley Company

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10
Controlled Production of Amyloid β Peptide from a Photo‐Triggered, Water‐Soluble Precursor “Click Peptide
Controlled Production of Amyloid β Peptide from a Photo‐Triggered, Water‐Soluble Precursor “Click Peptide
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Controlled Production of Amyloid β Peptide from a Photo‐Triggered, Water‐Soluble Precursor “Click Peptide

Taniguchi, Atsuhiko ; Skwarczynski, Mariusz ; Sohma, Youhei ; Okada, Takuma ; Ikeda, Keisuke ; Prakash, Halan ; Mukai, Hidehito ; Hayashi , Yoshio ; Kimura, Tooru ; Hirota, Shun ; Matsuzaki, Katsumi ; Kiso, Yoshiaki

Chembiochem : a European journal of chemical biology, 2008-12, Vol.9 (18), p.3055-3065 [Periódico revisado por pares]

Weinheim: WILEY‐VCH Verlag

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