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Shapiro, Robin
| Result Number | Material Type | Add to My Shelf Action | Record Details and Options |
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| 1 |
![Identification of 2-(4-Benzyloxyphenyl)-N- [1-(2-pyrrolidin-1-yl-ethyl)-1H-indazol-6-yl]acetamide, an Orally Efficacious Melanin-Concentrating Hormone Receptor 1 Antagonist for the Treatment of Obesity](../images/pixel.png){kind=tracking}
Material Type: Artigo
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Identification of 2-(4-Benzyloxyphenyl)-N- [1-(2-pyrrolidin-1-yl-ethyl)-1H-indazol-6-yl]acetamide, an Orally Efficacious Melanin-Concentrating Hormone Receptor 1 Antagonist for the Treatment of ObesitySouers, Andrew J ; Gao, Ju ; Brune, Michael ; Bush, Eugene ; Wodka, Dariusz ; Vasudevan, Anil ; Judd, Andrew S ; Mulhern, Mathew ; Brodjian, Sevan ; Dayton, Brian ; Shapiro, Robin ; Hernandez, Lisa E ; Marsh, Kennan C ; Sham, Hing L ; Collins, Christine A ; Kym, Philip RJournal of medicinal chemistry, 2005-03, Vol.48 (5), p.1318-1321 [Periódico revisado por pares]Washington, DC: American Chemical SocietyTexto completo disponível |
| 2 |
Material Type: Artigo
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2,4-Diaminopyrimidine Derivatives as Potent Growth Hormone Secretagogue Receptor AntagonistsSerby, Michael D. ; Zhao, Hongyu ; Szczepankiewicz, Bruce G. ; Kosogof, Christi ; Xin, Zhili ; Liu, Bo ; Liu, Mei ; Nelson, Lissa T. J. ; Kaszubska, Wiweka ; Falls, H. Douglas ; Schaefer, Verlyn ; Bush, Eugene N. ; Shapiro, Robin ; Droz, Brian A. ; Knourek-Segel, Victoria E. ; Fey, Thomas A. ; Brune, Michael E. ; Beno, David W. A. ; Turner, Theresa M. ; Collins, Christine A. ; Jacobson, Peer B. ; Sham, Hing L. ; Liu, GangJournal of medicinal chemistry, 2006-04, Vol.49 (8), p.2568-2578 [Periódico revisado por pares]Washington, DC: American Chemical SocietyTexto completo disponível |
| 3 |
Material Type: Artigo
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Synthesis and evaluation of urea-based indazoles as melanin-concentrating hormone receptor 1 antagonists for the treatment of obesitySouers, Andrew J. ; Gao, Ju ; Wodka, Dariusz ; Judd, Andrew S. ; Mulhern, Mathew M. ; Napier, James J. ; Brune, Michael E. ; Bush, Eugene N. ; Brodjian, Sevan J. ; Dayton, Brian D. ; Shapiro, Robin ; Hernandez, Lisa E. ; Marsh, Kennan C. ; Sham, Hing L. ; Collins, Christine A. ; Kym, Philip R.Bioorganic & medicinal chemistry letters, 2005-06, Vol.15 (11), p.2752-2757 [Periódico revisado por pares]Oxford: Elsevier LtdTexto completo disponível |
| 4 |
Material Type: Artigo
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Optimization of Chromone-2-carboxamide Melanin Concentrating Hormone Receptor 1 Antagonists: Assessment of Potency, Efficacy, and Cardiovascular SafetyLynch, John K ; Freeman, Jennifer C ; Judd, Andrew S ; Iyengar, Rajesh ; Mulhern, Mathew ; Zhao, Gang ; Napier, James J ; Wodka, Dariusz ; Brodjian, Sevan ; Dayton, Brian D ; Falls, Doug ; Ogiela, Christopher ; Reilly, Regina M ; Campbell, Thomas J ; Polakowski, James S ; Hernandez, Lisa ; Marsh, Kennan C ; Shapiro, Robin ; Knourek-Segel, Victoria ; Droz, Brian ; Bush, Eugene ; Brune, Michael ; Preusser, Lee C ; Fryer, Ryan M ; Reinhart, Glenn A ; Houseman, Kathryn ; Diaz, Gilbert ; Mikhail, Ann ; Limberis, James T ; Sham, Hing L ; Collins, Christine A ; Kym, Philip RJournal of medicinal chemistry, 2006-11, Vol.49 (22), p.6569-6584 [Periódico revisado por pares]Washington, DC: American Chemical SocietyTexto completo disponível |
| 5 |
Material Type: Artigo
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Aminopiperidine indazoles as orally efficacious melanin concentrating hormone receptor-1 antagonistsVasudevan, Anil ; Souers, Andrew J. ; Freeman, Jennifer C. ; Verzal, Mary K. ; Gao, Ju ; Mulhern, Mathew M. ; Wodka, Derek ; Lynch, John K. ; Engstrom, Kenneth M. ; Wagaw, Seble H. ; Brodjian, Sevan ; Dayton, Brian ; Falls, Doug H. ; Bush, Eugene ; Brune, Michael ; Shapiro, Robin D. ; Marsh, Kennan C. ; Hernandez, Lisa E. ; Collins, Christine A. ; Kym, Philip R.Bioorganic & medicinal chemistry letters, 2005-12, Vol.15 (23), p.5293-5297 [Periódico revisado por pares]Oxford: Elsevier LtdTexto completo disponível |
| 6 |
Material Type: Artigo
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Identification of ortho-amino benzamides and nicotinamides as MCHr1 antagonistsVasudevan, Anil ; LaMarche, Matthew J. ; Blackburn, Christopher ; Che, Jennifer Lee ; Luchaco-Cullis, Courtney A. ; Lai, Sujen ; Marsilje, Thomas H. ; Patane, Michael A. ; Souers, Andrew J. ; Wodka, Derek ; Geddes, Bradley ; Chen, Sumiao ; Brodjian, Seven ; Falls, Doug H. ; Dayton, Brian D. ; Bush, Eugene ; Brune, Michael ; Shapiro, Robin D. ; Marsh, Kennan C. ; Hernandez, Lisa E. ; Sham, Hing L. ; Collins, Christine A. ; Kym, Philip R.Bioorganic & medicinal chemistry letters, 2005-10, Vol.15 (19), p.4174-4179 [Periódico revisado por pares]Oxford: Elsevier LtdTexto completo disponível |
| 7 |
Material Type: Artigo
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Discovery and Pharmacological Evaluation of Growth Hormone Secretagogue Receptor AntagonistsXin, Zhili ; Serby, Michael D ; Zhao, Hongyu ; Kosogof, Christi ; Szczepankiewicz, Bruce G ; Liu, Mei ; Hutchins, Charles W ; Sarris, Kathy A ; Hoff, Ethan D ; Falls, H. Douglas ; Lin, Chun W ; Ogiela, Christopher A ; Collins, Christine A ; Brune, Michael E ; Bush, Eugene N ; Droz, Brian A ; Fey, Thomas A ; Knourek-Segel, Victoria E ; Shapiro, Robin ; Jacobson, Peer B ; Beno, David W. A ; Turner, Teresa M ; Sham, Hing L ; Liu, GangJournal of medicinal chemistry, 2006-07, Vol.49 (15), p.4459-4469 [Periódico revisado por pares]Washington, DC: American Chemical SocietyTexto completo disponível |
| 8 |
Material Type: Artigo
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Constrained 7-fluorocarboxychromone-4-aminopiperidine based Melanin-concentrating hormone receptor 1 antagonists: The effects of chirality on substituted indan-1-ylaminesSouers, Andrew J. ; Iyengar, Rajesh R. ; Judd, Andrew S. ; Beno, David W.A. ; Gao, Ju ; Zhao, Gang ; Brune, Michael E. ; Napier, James J. ; Mulhern, Mathew M. ; Lynch, John K. ; Freeman, Jennifer C. ; Wodka, Dariusz ; Chen, Chong J. ; Falls, H. Doug ; Brodjian, Sevan ; Dayton, Brian D. ; Diaz, Gilbert J. ; Bush, Eugene N. ; Shapiro, Robin ; Droz, Brian A. ; Knourek-Segel, Victoria ; Hernandez, Lisa E. ; Marsh, Kennan C. ; Reilly, Regina M. ; Sham, Hing L. ; Collins, Christine A. ; Kym, Philip R.Bioorganic & medicinal chemistry letters, 2007-02, Vol.17 (4), p.884-889 [Periódico revisado por pares]Oxford: Elsevier LtdTexto completo disponível |
| 9 |
Material Type: Artigo
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Identification of diamino chromone-2-carboxamides as MCHr1 antagonists with minimal hERG channel activityJudd, Andrew S. ; Souers, Andrew J. ; Wodka, Dariusz ; Zhao, Gang ; Mulhern, Mathew M. ; Iyengar, Rajesh R. ; Gao, Ju ; Lynch, John K. ; Freeman, Jennifer C. ; Falls, H. Douglas ; Brodjian, Sevan ; Dayton, Brian D. ; Reilly, Regina M. ; Gintant, Gary ; Limberis, James T. ; Mikhail, Ann ; Leitza, Sandra T. ; Houseman, Kathryn A. ; Diaz, Gilbert ; Bush, Eugene N. ; Shapiro, Robin ; Knourek-Segel, Victoria ; Hernandez, Lisa E. ; Marsh, Kennan C. ; Sham, Hing L. ; Collins, Christine A. ; Kym, Philip R.Bioorganic & medicinal chemistry letters, 2007-04, Vol.17 (8), p.2365-2371 [Periódico revisado por pares]Oxford: Elsevier LtdTexto completo disponível |
| 10 |
Material Type: Artigo
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Chronic treatment with either dexfenfluramine or sibutramine in diet-switched diet-induced obese miceBush, Eugene N ; Shapiro, Robin ; Brune, Michael E ; Knourek-Segel, Victoria E ; Droz, Brian A ; Fey, Thomas ; Lin, Emily ; Jacobson, Peer BEndocrine, 2006-04, Vol.29 (2), p.375-382 [Periódico revisado por pares]United StatesTexto completo disponível |
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