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1
Prospective, randomized, double-blind, Phase 2 dose-ranging study comparing efficacy and safety of imipenem/cilastatin plus relebactam with imipenem/cilastatin alone in patients with complicated urinary tract infections
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Prospective, randomized, double-blind, Phase 2 dose-ranging study comparing efficacy and safety of imipenem/cilastatin plus relebactam with imipenem/cilastatin alone in patients with complicated urinary tract infections

Sims, Matthew ; Mariyanovski, Valeri ; McLeroth, Patrick ; Akers, Wayne ; Lee, Yu-Chieh ; Brown, Michelle L ; Du, Jiejun ; Pedley, Alison ; Kartsonis, Nicholas A ; Paschke, Amanda

Journal of antimicrobial chemotherapy, 2017-09, Vol.72 (9), p.2616-2626 [Periódico revisado por pares]

England: Oxford University Press (OUP)

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2
Comparison of Treatment Outcomes between Analysis Populations in the RESTORE-IMI 1 Phase 3 Trial of Imipenem-Cilastatin-Relebactam versus Colistin plus Imipenem-Cilastatin in Patients with Imipenem-Nonsusceptible Bacterial Infections
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Comparison of Treatment Outcomes between Analysis Populations in the RESTORE-IMI 1 Phase 3 Trial of Imipenem-Cilastatin-Relebactam versus Colistin plus Imipenem-Cilastatin in Patients with Imipenem-Nonsusceptible Bacterial Infections

Kaye, Keith S ; Boucher, Helen W ; Brown, Michelle L ; Aggrey, Angela ; Khan, Ireen ; Joeng, Hee-Koung ; Tipping, Robert W ; Du, Jiejun ; Young, Katherine ; Butterton, Joan R ; Paschke, Amanda

Antimicrobial agents and chemotherapy, 2020-04, Vol.64 (5) [Periódico revisado por pares]

United States: American Society for Microbiology

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3
1951. Nephrotoxicity Associated With Imipenem/Cilastatin/Relebactam (IMI/REL) vs. Imipenem/Cilastatin Plus Colistin (IMI+CST) in Patients With Imipenem-Nonsusceptible (NS) Bacterial Infections
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1951. Nephrotoxicity Associated With Imipenem/Cilastatin/Relebactam (IMI/REL) vs. Imipenem/Cilastatin Plus Colistin (IMI+CST) in Patients With Imipenem-Nonsusceptible (NS) Bacterial Infections

Brown, Michelle ; Motsch, Johann ; Kaye, Keith ; File, Thomas ; Boucher, Helen W ; Vendetti, Neika ; Aggrey, Angela ; Joeng, Hee-Koung ; Tipping, Robert ; Du, Jiejun ; Depestel, Daryl D ; Butterton, Joan ; Kartsonis, Nicholas A ; Paschke, Amanda

Open forum infectious diseases, 2018-11, Vol.5 (suppl_1), p.S563-S563 [Periódico revisado por pares]

US: Oxford University Press (OUP)

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4
1339. Results for the Supplemental Microbiological Modified Intent-to-Treat (SmMITT) Population of the RESTORE-IMI 1 Trial of Imipenem/Cilastatin/Relebactam (IMI/REL) vs. Imipenem/Cilastatin Plus Colistin (IMI+CST) in Patients with Imipenem-Nonsusceptible (NS) Bacterial Infections
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1339. Results for the Supplemental Microbiological Modified Intent-to-Treat (SmMITT) Population of the RESTORE-IMI 1 Trial of Imipenem/Cilastatin/Relebactam (IMI/REL) vs. Imipenem/Cilastatin Plus Colistin (IMI+CST) in Patients with Imipenem-Nonsusceptible (NS) Bacterial Infections

Kaye, Keith ; File, Thomas ; Boucher, Helen W ; Brown, Michelle ; Aggrey, Angela ; Khan, Ireen ; Joeng, Hee-Koung ; Tipping, Robert ; Du, Jiejun ; Young, Katherine ; Butterton, Joan ; Kartsonis, Nicholas A ; Paschke, Amanda

Open forum infectious diseases, 2018-11, Vol.5 (suppl_1), p.S409-S409 [Periódico revisado por pares]

US: Oxford University Press (OUP)

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5
Evaluation of Renal Safety Between Imipenem/Relebactam and Colistin Plus Imipenem in Patients With Imipenem-Nonsusceptible Bacterial Infections in the Randomized, Phase 3 RESTORE-IMI 1 Study
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Evaluation of Renal Safety Between Imipenem/Relebactam and Colistin Plus Imipenem in Patients With Imipenem-Nonsusceptible Bacterial Infections in the Randomized, Phase 3 RESTORE-IMI 1 Study

Brown, Michelle L ; Motsch, Johann ; Kaye, Keith S ; File, Thomas M ; Boucher, Helen W ; Vendetti, Neika ; Aggrey, Angela ; Joeng, Hee-Koung ; Tipping, Robert W ; Du, Jiejun ; DePestel, Daryl D ; Butterton, Joan R ; Paschke, Amanda

Open forum infectious diseases, 2020-03, Vol.7 (3), p.ofaa054 [Periódico revisado por pares]

US: Oxford University Press

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6
Phase 2, Dose-Ranging Study of Relebactam with Imipenem-Cilastatin in Subjects with Complicated Intra-abdominal Infection
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Phase 2, Dose-Ranging Study of Relebactam with Imipenem-Cilastatin in Subjects with Complicated Intra-abdominal Infection

Lucasti, Christopher ; Vasile, Liviu ; Sandesc, Dorel ; Venskutonis, Donatas ; McLeroth, Patrick ; Lala, Mallika ; Rizk, Matthew L ; Brown, Michelle L ; Losada, Maria C ; Pedley, Alison ; Kartsonis, Nicholas A ; Paschke, Amanda

Antimicrobial agents and chemotherapy, 2016-10, Vol.60 (10), p.6234-6243 [Periódico revisado por pares]

United States: American Society for Microbiology

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7
Participant- and Disease-Related Factors as Independent Predictors of Treatment Outcomes in the RESTORE-IMI 2 Clinical Trial: A Multivariable Regression Analysis
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Participant- and Disease-Related Factors as Independent Predictors of Treatment Outcomes in the RESTORE-IMI 2 Clinical Trial: A Multivariable Regression Analysis

Martin-Loeches, Ignacio ; Shorr, Andrew F ; Kollef, Marin H ; Du, Jiejun ; Losada, Maria C ; Paschke, Amanda ; DeRyke, C Andrew ; Wong, Michael ; Jensen, Erin H ; Chen, Luke F

Open forum infectious diseases, 2023-06, Vol.10 (6), p.ofad225-ofad225 [Periódico revisado por pares]

US: Oxford University Press

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8
Simplification of Imipenem Dosing by Removal of Weight‐Based Adjustments
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Simplification of Imipenem Dosing by Removal of Weight‐Based Adjustments

Lala, Mallika ; Brown, Michelle ; Kantesaria, Bhavna ; Walker, Brittany ; Paschke, Amanda ; Rizk, Matthew L.

Journal of clinical pharmacology, 2019-05, Vol.59 (5), p.646-653 [Periódico revisado por pares]

England: American College of Clinical Pharmacology

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