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The family-wide structure and function of human dual-specificity protein phosphatases
The family-wide structure and function of human dual-specificity protein phosphatases
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The family-wide structure and function of human dual-specificity protein phosphatases

Jeong, Dae Gwin ; Wei, Chun Hua ; Ku, Bonsu ; Jeon, Tae Jin ; Chien, Pham Ngoc ; Kim, Jae Kwan ; Park, So Ya ; Hwang, Hyun Sook ; Ryu, Sun Young ; Park, Hwangseo ; Kim, Deok-Soo ; Kim, Seung Jun ; Ryu, Seong Eon

Acta crystallographica. Section D, Biological crystallography., 2014-02, Vol.70 (2), p.421-435 [Periódico revisado por pares]

5 Abbey Square, Chester, Cheshire CH1 2HU, England: International Union of Crystallography

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2
Discovery of Novel DUSP16 Phosphatase Inhibitors through Virtual Screening with Homology Modeled Protein Structure
Discovery of Novel DUSP16 Phosphatase Inhibitors through Virtual Screening with Homology Modeled Protein Structure
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Discovery of Novel DUSP16 Phosphatase Inhibitors through Virtual Screening with Homology Modeled Protein Structure

Park, Hwangseo ; Park, So Ya ; Nam, Sang-Won ; Ryu, Seong Eon

Journal of biomolecular screening, 2014-12, Vol.19 (10), p.1383-1390 [Periódico revisado por pares]

Los Angeles, CA: SAGE Publications

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3
Exploring binding sites other than the catalytic core in the crystal structure of the catalytic domain of MKP-4
Exploring binding sites other than the catalytic core in the crystal structure of the catalytic domain of MKP-4
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Exploring binding sites other than the catalytic core in the crystal structure of the catalytic domain of MKP-4

Jeong, Dae Gwin ; Yoon, Tae Sung ; Jung, Suk-Kyeong ; Park, Byoung Cheol ; Park, Hwangseo ; Ryu, Seong Eon ; Kim, Seung Jun

Acta crystallographica. Section D, Biological crystallography., 2011-01, Vol.67 (1), p.25-31 [Periódico revisado por pares]

5 Abbey Square, Chester, Cheshire CH1 2HU, England: International Union of Crystallography

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4
Structural basis for the dephosphorylating activity of PTPRQ towards phosphatidylinositide substrates
Structural basis for the dephosphorylating activity of PTPRQ towards phosphatidylinositide substrates
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Structural basis for the dephosphorylating activity of PTPRQ towards phosphatidylinositide substrates

Yu, Keum Ran ; Kim, Young Jun ; Jung, Suk-Kyeong ; Ku, Bonsu ; Park, Hwangseo ; Cho, Sa Yeon ; Jung, Hyeyun ; Chung, Sang J. ; Bae, Kwang Hee ; Lee, Sang Chul ; Kim, Bo Yeon ; Erikson, Raymond L. ; Ryu, Seong Eon ; Kim, Seung Jun

Acta crystallographica. Section D, Biological crystallography., 2013-08, Vol.69 (8), p.1522-1529 [Periódico revisado por pares]

5 Abbey Square, Chester, Cheshire CH1 2HU, England: International Union of Crystallography

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5
Identification of novel protein tyrosine phosphatase sigma inhibitors promoting neurite extension
Identification of novel protein tyrosine phosphatase sigma inhibitors promoting neurite extension
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Identification of novel protein tyrosine phosphatase sigma inhibitors promoting neurite extension

Lee, Hye Seon ; Ku, Bonsu ; Park, Tae Hyun ; Park, Hwangseo ; Choi, Joong-Kwon ; Chang, Kyu-Tae ; Kim, Cheol-Hee ; Ryu, Seong Eon ; Kim, Seung Jun

Bioorganic & medicinal chemistry letters, 2016-01, Vol.26 (1), p.87-93 [Periódico revisado por pares]

England: Elsevier Ltd

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6
Critical assessment of the automated AutoDock as a new docking tool for virtual screening
Critical assessment of the automated AutoDock as a new docking tool for virtual screening
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Critical assessment of the automated AutoDock as a new docking tool for virtual screening

Park, Hwangseo ; Lee, Jinuk ; Lee, Sangyoub

Proteins, structure, function, and bioinformatics, 2006-11, Vol.65 (3), p.549-554 [Periódico revisado por pares]

Hoboken: Wiley Subscription Services, Inc., A Wiley Company

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7
Structure-based virtual screening approach to identify novel classes of PTP1B inhibitors
Structure-based virtual screening approach to identify novel classes of PTP1B inhibitors
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Structure-based virtual screening approach to identify novel classes of PTP1B inhibitors

Park, Hwangseo ; Bhattarai, Bharat Raj ; Ham, Seung Wook ; Cho, Hyeongjin

European journal of medicinal chemistry, 2009-08, Vol.44 (8), p.3280-3284 [Periódico revisado por pares]

Kidlington: Elsevier Masson SAS

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8
Identification of novel PTPRQ phosphatase inhibitors based on the virtual screening with docking simulations
Identification of novel PTPRQ phosphatase inhibitors based on the virtual screening with docking simulations
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Identification of novel PTPRQ phosphatase inhibitors based on the virtual screening with docking simulations

Park, Hwangseo ; Yu, Keum Ran ; Ku, Bonsu ; Kim, Bo Yeon ; Kim, Seung Jun

Theoretical biology and medical modelling, 2013-08, Vol.10 (1), p.49-49, Article 49 [Periódico revisado por pares]

England: BioMed Central Ltd

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9
Novel thiazolidinedione derivatives with anti-obesity effects: Dual action as PTP1B inhibitors and PPAR-γ activators
Novel thiazolidinedione derivatives with anti-obesity effects: Dual action as PTP1B inhibitors and PPAR-γ activators
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Novel thiazolidinedione derivatives with anti-obesity effects: Dual action as PTP1B inhibitors and PPAR-γ activators

Bhattarai, Bharat Raj ; Kafle, Bhooshan ; Hwang, Ji-Sun ; Ham, Seung Wook ; Lee, Keun-Hyeung ; Park, Hwangseo ; Han, Inn-Oc ; Cho, Hyeongjin

Bioorganic & medicinal chemistry letters, 2010-11, Vol.20 (22), p.6758-6763 [Periódico revisado por pares]

Amsterdam: Elsevier Ltd

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10
Discovery of potent inhibitors of receptor protein tyrosine phosphatase sigma through the structure-based virtual screening
Discovery of potent inhibitors of receptor protein tyrosine phosphatase sigma through the structure-based virtual screening
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Discovery of potent inhibitors of receptor protein tyrosine phosphatase sigma through the structure-based virtual screening

Park, Hwangseo ; Chien, Pham Ngoc ; Ryu, Seong Eon

Bioorganic & medicinal chemistry letters, 2012-10, Vol.22 (20), p.6333-6337 [Periódico revisado por pares]

Amsterdam: Elsevier Ltd

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