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Height, body mass index, and socioeconomic status: mendelian randomisation study in UK Biobank

Tyrrell, Jessica ; Jones, Samuel E ; Beaumont, Robin ; Astley, Christina M ; Lovell, Rebecca ; Yaghootkar, Hanieh ; Tuke, Marcus ; Ruth, Katherine S ; Freathy, Rachel M ; Hirschhorn, Joel N ; Wood, Andrew R ; Murray, Anna ; Weedon, Michael N ; Frayling, Timothy M

BMJ, 8 March 2016, Vol.352 [Periódico revisado por pares]

British Medical Journal Publishing Group

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Another explanation for apparent epistasis

Andrew R. Wood ; Marcus A. Tuke ; Mike A. Nalls ; Dena G. Hernandez ; Stefania Bandinelli ; Andrew B. Singleton ; David Melzer ; Luigi Ferrucci ; Timothy M. Frayling ; Michael N. Weedon

Nature, 2014, Vol.514(7520), p.E3 [Periódico revisado por pares]

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Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively

Wood, Andrew ; Tyrrell, Jessica ; Beaumont, Robin ; Jones, Samuel ; Tuke, Marcus ; Ruth, Katherine ; Yaghootkar, Hanieh ; Freathy, Rachel ; Murray, Anna ; Frayling, Timothy ; Weedon, Michael

Diabetologia, 2016, Vol.59(6), pp.1214-1221 [Periódico revisado por pares]

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4
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Genetic evidence that lower circulating FSH levels lengthen menstrual cycle, increase age at menopause and impact female reproductive health

Ruth, Katherine S ; Beaumont, Robin N ; Tyrrell, Jessica ; Jones, Samuel E ; Tuke, Marcus A ; Yaghootkar, Hanieh ; Wood, Andrew R ; Freathy, Rachel M ; Weedon, Michael N ; Frayling, Timothy M ; Murray, Anna

Human Reproduction, 2016, Vol. 31(2), pp.473-481 [Periódico revisado por pares]

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Defining the role of common variation in the genomic and biological architecture of adult human height

Andrew R Wood ; Tonu Esko ; Jian Yang ; Sailaja Vedantam ; Tune H Pers ; Stefan Gustafsson ; Audrey Y Chu ; Karol Estrada ; Jian'An Luan ; Zoltán Kutalik ; Najaf Amin ; Martin L Buchkovich ; Damien C Croteau-Chonka ; Felix R Day ; Yanan Duan ; Tove Fall ; Rudolf Fehrmann ; Teresa Ferreira ; Anne U Jackson ; Juha Karjalainen ; Ken Sin Lo ; Adam E Locke ; Reedik Mägi ; Evelin Mihailov ; Eleonora Porcu ; Joshua C Randall ; André Scherag ; Anna A E Vinkhuyzen ; Harm-Jan Westra ; Thomas W Winkler ; Tsegaselassie Workalemahu ; Jing Hua Zhao ; Devin Absher ; Eva Albrecht ; Denise Anderson ; Jeffrey Baron ; Marian Beekman ; Ayse Demirkan ; Georg B Ehret ; Bjarke Feenstra ; Mary F Feitosa ; Krista Fischer ; Ross M Fraser ; Anuj Goel ; Jian Gong ; Anne E Justice ; Stavroula Kanoni ; Marcus E Kleber ; Kati Kristiansson ; Unhee Lim ; Vaneet Lotay ; Julian C Lui ; Massimo Mangino ; Irene Mateo Leach ; Carolina Medina-Gomez ; Michael A Nalls ; Dale R Nyholt ; Cameron D Palmer ; Dorota Pasko ; Sonali Pechlivanis ; Inga Prokopenko ; Janina S Ried ; Stephan Ripke ; Dmitry Shungin ; Alena Stancáková ; Rona J Strawbridge ; Yun Ju Sung ; Toshiko Tanaka ; Alexander Teumer ; Stella Trompet ; Sander W Van Der Laan ; Jessica Van Setten ; Jana V Van Vliet-Ostaptchouk ; Zhaoming Wang ; Loïc Yengo ; Weihua Zhang ; Uzma Afzal ; Johan Ärnlöv ; Gillian M Arscott ; Stefania Bandinelli ; Amy Barrett ; Claire Bellis ; Amanda J Bennett ; Christian Berne ; Matthias Blüher ; Jennifer L Bolton ; Yvonne Böttcher ; Heather A Boyd ; Marcel Bruinenberg ; Brendan M Buckley ; Steven Buyske ; Ida H Caspersen ; Peter S Chines ; Robert Clarke ; Simone Claudi-Boehm ; Matthew Cooper ; E Warwick Daw ; Pim A De Jong ; Joris Deelen ; Graciela Delgado ; Josh C Denny ; Rosalie Dhonukshe-Rutten ; Maria Dimitriou ; Alex S F Doney ; Marcus Dörr ; Niina Eklund ; Elodie Eury ; Lasse Folkersen ; Melissa E Garcia ; Frank Geller ; Vilmantas Giedraitis ; Alan S Go ; Harald Grallert ; Tanja B Grammer ; Jürgen Gräßler ; Henrik Grönberg ; Lisette C P G M De Groot ; Christopher J Groves ; Jeffrey Haessler ; Per Hall ; Toomas Haller ; Goran Hallmans ; Anke Hannemann ; Catharina A Hartman ; Maija Hassinen ; Caroline Hayward ; Nancy L Heard-Costa ; Quinta Helmer ; Gibran Hemani ; Anjali K Henders ; Hans L Hillege ; Mark A Hlatky ; Wolfgang Hoffmann ; Per Hoffmann ; Oddgeir Holmen ; Jeanine J Houwing-Duistermaat ; Thomas Illig ; Aaron Isaacs ; Alan L James ; Janina Jeff ; Berit Johansen ; Åsa Johansson ; Jennifer Jolley ; Thorhildur Juliusdottir ; Juhani Junttila ; Abel N Kho ; Leena Kinnunen ; Norman Klopp ; Thomas Kocher ; Wolfgang Kratzer ; Peter Lichtner ; Lars Lind ; Jaana Lindström ; Stéphane Lobbens ; Mattias Lorentzon ; Yingchang Lu ; Valeriya Lyssenko ; Patrik K E Magnusson ; Anubha Mahajan ; Marc Maillard ; Wendy L Mcardle ; Colin A Mckenzie ; Stela Mclachlan ; Paul J Mclaren ; Cristina Menni ; Sigrun Merger ; Lili Milani ; Alireza Moayyeri ; Keri L Monda ; Mario A Morken ; Gabriele Müller ; Martina Müller-Nurasyid ; Arthur W Musk ; Narisu Narisu ; Matthias Nauck ; Ilja M Nolte ; Markus M Nöthen ; Laticia Oozageer ; Stefan Pilz ; Nigel W Rayner ; Frida Renstrom ; Neil R Robertson ; Lynda M Rose ; Ronan Roussel ; Serena Sanna ; Hubert Scharnagl ; Salome Scholtens ; Fredrick R Schumacher ; Heribert Schunkert ; Robert A Scott ; Joban Sehmi ; Thomas Seufferlein ; Jianxin Shi ; Karri Silventoinen ; Johannes H Smit ; Albert Vernon Smith ; Joanna Smolonska ; Alice V Stanton ; Kathleen Stirrups ; David J Stott ; Heather M Stringham ; Johan Sundström ; Morris A Swertz ; Ann-Christine Syvänen ; Bamidele O Tayo ; Gudmar Thorleifsson ; Jonathan P Tyrer ; Suzanne Van Dijk ; Natasja M Van Schoor ; Nathalie Van Der Velde ; Diana Van Heemst ; Floor V A Van Oort ; Sita H Vermeulen ; Niek Verweij ; Judith M Vonk ; Lindsay L Waite ; Melanie Waldenberger ; Roman Wennauer ; Lynne R Wilkens ; Christina Willenborg ; Tom Wilsgaard ; Mary K Wojczynski ; Andrew Wong ; Alan F Wright ; Qunyuan Zhang ; Dominique Arveiler ; Stephan J L Bakker ; John Beilby ; Richard N Bergman ; Sven Bergmann ; Reiner Biffar ; John Blangero ; Dorret I Boomsma ; Stefan R Bornstein ; Pascal Bovet ; Paolo Brambilla ; Morris J Brown ; Harry Campbell ; Mark J Caulfield ; Aravinda Chakravarti ; Rory Collins ; Francis S Collins ; Dana C Crawford ; L Adrienne Cupples ; John Danesh ; Ulf De Faire ; Hester M Den Ruijter ; Raimund Erbel ; Jeanette Erdmann ; Johan G Eriksson ; Martin Farrall ; Ele Ferrannini ; Jean Ferrières ; Ian Ford ; Nita G Forouhi ; Terrence Forrester ; Ron T Gansevoort ; Pablo V Gejman ; Christian Gieger ; Alain Golay ; Omri Gottesman ; Vilmundur Gudnason ; Ulf Gyllensten ; David W Haas ; Alistair S Hall ; Tamara B Harris ; Andrew T Hattersley ; Andrew C Heath ; Christian Hengstenberg ; Andrew A Hicks ; Lucia A Hindorff ; Aroon D Hingorani ; Albert Hofman ; G Kees Hovingh ; Steve E Humphries ; Steven C Hunt ; Elina Hypponen ; Kevin B Jacobs ; Marjo-Riitta Jarvelin ; Pekka Jousilahti ; Antti M Jula ; Jaakko Kaprio ; John J P Kastelein ; Manfred Kayser ; Frank Kee ; Sirkka M Keinanen-Kiukaanniemi ; Lambertus A Kiemeney ; Jaspal S Kooner ; Charles Kooperberg ; Seppo Koskinen ; Peter Kovacs ; Aldi T Kraja ; Meena Kumari ; Johanna Kuusisto ; Timo A Lakka ; Claudia Langenberg ; Loic Le Marchand ; Terho Lehtimäki ; Sara Lupoli ; Pamela A F Madden ; Satu Männistö ; Paolo Manunta ; André Marette ; Tara C Matise ; Barbara Mcknight ; Thomas Meitinger ; Frans L Moll ; Grant W Montgomery ; Andrew D Morris ; Andrew P Morris ; Jeffrey C Murray ; Mari Nelis ; Claes Ohlsson ; Albertine J Oldehinkel ; Ken K Ong ; Willem H Ouwehand ; Gerard Pasterkamp ; Annette Peters ; Peter P Pramstaller ; Jackie F Price ; Lu Qi ; Olli T Raitakari ; Tuomo Rankinen ; D C Rao ; Treva K Rice ; Marylyn Ritchie ; Igor Rudan ; Veikko Salomaa ; Nilesh J Samani ; Jouko Saramies ; Mark A Sarzynski ; Peter E H Schwarz ; Sylvain Sebert ; Peter Sever ; Alan R Shuldiner ; Juha Sinisalo ; Valgerdur Steinthorsdottir ; Ronald P Stolk ; Jean-Claude Tardif ; Anke Tönjes ; Angelo Tremblay ; Elena Tremoli ; Jarmo Virtamo ; Marie-Claude Vohl ; Philippe Amouyel ; Folkert W Asselbergs ; Themistocles L Assimes ; Murielle Bochud ; Bernhard O Boehm ; Eric Boerwinkle ; Erwin P Bottinger ; Claude Bouchard ; Stéphane Cauchi ; John C Chambers ; Stephen J Chanock ; Richard S Cooper ; Paul I W De Bakker ; George Dedoussis ; Luigi Ferrucci ; Paul W Franks ; Philippe Froguel ; Leif C Groop ; Christopher A Haiman ; Anders Hamsten ; M Geoffrey Hayes ; Jennie Hui ; David J Hunter ; Kristian Hveem ; J Wouter Jukema ; Robert C Kaplan ; Mika Kivimaki ; Diana Kuh ; Markku Laakso ; Yongmei Liu ; Nicholas G Martin ; Winfried März ; Mads Melbye ; Susanne Moebus ; Patricia B Munroe ; Inger Njølstad ; Ben A Oostra ; Colin N A Palmer ; Nancy L Pedersen ; Markus Perola ; Louis Pérusse ; Ulrike Peters ; Joseph E Powell ; Chris Power ; Thomas Quertermous ; Rainer Rauramaa ; Eva Reinmaa ; Paul M Ridker ; Fernando Rivadeneira ; Jerome I Rotter ; Timo E Saaristo ; Danish Saleheen ; David Schlessinger ; P Eline Slagboom ; Harold Snieder ; Tim D Spector ; Konstantin Strauch ; Michael Stumvoll ; Jaakko Tuomilehto ; Matti Uusitupa ; Pim Van Der Harst ; Henry Völzke ; Mark Walker ; Nicholas J Wareham ; Hugh Watkins ; H-Erich Wichmann ; James F Wilson ; Pieter Zanen ; Panos Deloukas ; Iris M Heid ; Cecilia M Lindgren ; Karen L Mohlke ; Elizabeth K Speliotes ; Unnur Thorsteinsdottir ; Inês Barroso ; Caroline S Fox ; Kari E North ; David P Strachan ; Jacques S Beckmann ; Sonja I Berndt ; Michael Boehnke ; Ingrid B Borecki ; Mark I Mccarthy ; Andres Metspalu ; Kari Stefansson ; André G Uitterlinden ; Cornelia M Van Duijn ; Lude Franke ; Cristen J Willer ; Alkes L Price ; Guillaume Lettre ; Ruth J F Loos ; Michael N Weedon ; Erik Ingelsson ; Jeffrey R O'Connell ; Goncalo R Abecasis ; Daniel I Chasman ; Michael E Goddard ; Peter M Visscher ; Joel N Hirschhorn ; Timothy M Frayling

Nature Genetics, 2014 [Periódico revisado por pares]

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Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based imputation

Andrew R Wood ; John R B Perry ; Toshiko Tanaka ; Dena G Hernandez ; Hou-Feng Zheng ; David Melzer ; J Raphael Gibbs ; Michael A Nalls ; Michael N Weedon ; Tim D Spector ; J Brent Richards ; Stefania Bandinelli ; Luigi Ferrucci ; Andrew B Singleton ; Timothy M Frayling

PLoS ONE, 01 January 2013, Vol.8(5), p.e64343 [Periódico revisado por pares]

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7
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Gene–obesogenic environment interactions in the UK Biobank study

Tyrrell, Jessica ; Wood, Andrew R ; Ames, Ryan M ; Yaghootkar, Hanieh ; Beaumont, Robin N ; Jones, Samuel E ; Tuke, Marcus A ; Ruth, Katherine S ; Freathy, Rachel M ; Davey Smith, George ; Joost, Stéphane ; Guessous, Idris ; Murray, Anna ; Strachan, David P ; Kutalik, Zoltán ; Weedon, Michael N ; Frayling, Timothy M

International Journal of Epidemiology, 2017, Vol. 46(2), pp.559-575 [Periódico revisado por pares]

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8
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Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers

Luke C Pilling ; Janice L Atkins ; Michael O Duff ; Robin N Beaumont ; Samuel E Jones ; Jessica Tyrrell ; Chia-Ling Kuo ; Katherine S Ruth ; Marcus A Tuke ; Hanieh Yaghootkar ; Andrew R Wood ; Anna Murray ; Michael N Weedon ; Lorna W Harries ; George A Kuchel ; Luigi Ferrucci ; Timothy M Frayling ; David Melzer

PLoS ONE, 01 January 2017, Vol.12(9), p.e0185083 [Periódico revisado por pares]

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9
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Association analysis of 29,956 individuals confirms that a low-frequency variant at CCND2 halves the risk of type 2 diabetes by enhancing insulin secretion

Yaghootkar, Hanieh ; Stancáková, Alena ; Freathy, Rachel M ; Vangipurapu, Jagadish ; Weedon, Michael N ; Xie, Weijia ; Wood, Andrew R ; Ferrannini, Ele ; Mari, Andrea ; Ring, Susan M ; Lawlor, Debbie A ; Davey Smith, George ; Jørgensen, Torben ; Hansen, Torben ; Pedersen, Oluf ; Steinthorsdottir, Valgerdur ; Guðbjartsson, Daniel F ; Thorleifsson, Gudmar ; Thorsteinsdottir, Unnur ; Stefansson, Kari ; Hattersley, Andrew T ; Walker, Mark ; Morris, Andrew D ; Mccarthy, Mark I ; Palmer, Colin N A ; Laakso, Markku ; Frayling, Timothy M

Diabetes, June 2015, Vol.64(6), pp.2279-85 [Periódico revisado por pares]

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10
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Genetic evidence for a link between favorable adiposity and lower risk of type 2 diabetes, hypertension and heart disease.

Yaghootkar, Hanieh ; Lotta, Luca Andrea ; Tyrrell, Jessica ; Smit, Roelof AJ ; Jones, Sam E ; Donnelly, Louise ; Beaumont, Robin ; Campbell, Archie ; Tuke, Marcus A ; Hayward, Caroline ; Ruth, Katherine S ; Padmanabhan, Sandosh ; Jukema, J Wouter ; Palmer, Colin C ; Hattersley, Andrew ; Freathy, Rachel M ; Langenberg, Claudia ; Wareham, Nicholas John ; Wood, Andrew R ; Murray, Anna ; Weedon, Michael N ; Sattar, Naveed ; Pearson, Ewan ; Scott, Robert ; Frayling, Timothy M Apollo - University of Cambridge Repository; Apollo - University of Cambridge Repository

Apollo - University of Cambridge Repository 2016

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Deste Autor:

  1. Frayling, Timothy M.
  2. Wood, Andrew R.
  3. Wood, Ar
  4. Weedon, Michael N
  5. Tyrrell, Jessica

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