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The role of astrocytic glutamate transporters GLT-1 and GLAST in neurological disorders: Potential targets for neurotherapeutics
The role of astrocytic glutamate transporters GLT-1 and GLAST in neurological disorders: Potential targets for neurotherapeutics
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The role of astrocytic glutamate transporters GLT-1 and GLAST in neurological disorders: Potential targets for neurotherapeutics

Pajarillo, Edward ; Rizor, Asha ; Lee, Jayden ; Aschner, Michael ; Lee, Eunsook

Neuropharmacology, 2019-12, Vol.161, p.107559-107559, Article 107559 [Periódico revisado por pares]

England: Elsevier Ltd

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Valproic acid attenuates manganese-induced reduction in expression of GLT-1 and GLAST with concomitant changes in murine dopaminergic neurotoxicity
Valproic acid attenuates manganese-induced reduction in expression of GLT-1 and GLAST with concomitant changes in murine dopaminergic neurotoxicity
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Valproic acid attenuates manganese-induced reduction in expression of GLT-1 and GLAST with concomitant changes in murine dopaminergic neurotoxicity

Johnson, James ; Pajarillo, Edward ; Karki, Pratap ; Kim, Judong ; Son, Deok-Soo ; Aschner, Michael ; Lee, Eunsook

Neurotoxicology (Park Forest South), 2018-07, Vol.67, p.112-120 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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Astrocyte-specific deletion of the transcription factor Yin Yang 1 in murine substantia nigra mitigates manganese-induced dopaminergic neurotoxicity
Astrocyte-specific deletion of the transcription factor Yin Yang 1 in murine substantia nigra mitigates manganese-induced dopaminergic neurotoxicity
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Astrocyte-specific deletion of the transcription factor Yin Yang 1 in murine substantia nigra mitigates manganese-induced dopaminergic neurotoxicity

Pajarillo, Edward ; Johnson, James ; Rizor, Asha ; Nyarko-Danquah, Ivan ; Adinew, Getinet ; Bornhorst, Julia ; Stiboller, Michael ; Schwerdtle, Tania ; Son, Deok-Soo ; Aschner, Michael ; Lee, Eunsook

The Journal of biological chemistry, 2020-11, Vol.295 (46), p.15662-15676 [Periódico revisado por pares]

United States: Elsevier Inc

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4
Manganese-induced reactive oxygen species activate IκB kinase to upregulate YY1 and impair glutamate transporter EAAT2 function in human astrocytes in vitro
Manganese-induced reactive oxygen species activate IκB kinase to upregulate YY1 and impair glutamate transporter EAAT2 function in human astrocytes in vitro
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Manganese-induced reactive oxygen species activate IκB kinase to upregulate YY1 and impair glutamate transporter EAAT2 function in human astrocytes in vitro

Rizor, Asha ; Pajarillo, Edward ; Nyarko-Danquah, Ivan ; Digman, Alexis ; Mooneyham, Leyah ; Son, Deok-Soo ; Aschner, Michael ; Lee, Eunsook

Neurotoxicology (Park Forest South), 2021-09, Vol.86, p.94-103 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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5
Arundic Acid Increases Expression and Function of Astrocytic Glutamate Transporter EAAT1 Via the ERK, Akt, and NF-κB Pathways
Arundic Acid Increases Expression and Function of Astrocytic Glutamate Transporter EAAT1 Via the ERK, Akt, and NF-κB Pathways
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Arundic Acid Increases Expression and Function of Astrocytic Glutamate Transporter EAAT1 Via the ERK, Akt, and NF-κB Pathways

Karki, Pratap ; Hong, Peter ; Johnson, James ; Pajarillo, Edward ; Son, Deok-Soo ; Aschner, Michael ; Lee, Eunsook Y.

Molecular neurobiology, 2018-06, Vol.55 (6), p.5031-5046 [Periódico revisado por pares]

New York: Springer US

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6
Astrocytic transcription factor REST upregulates glutamate transporter EAAT2, protecting dopaminergic neurons from manganese-induced excitotoxicity
Astrocytic transcription factor REST upregulates glutamate transporter EAAT2, protecting dopaminergic neurons from manganese-induced excitotoxicity
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Astrocytic transcription factor REST upregulates glutamate transporter EAAT2, protecting dopaminergic neurons from manganese-induced excitotoxicity

Pajarillo, Edward ; Digman, Alexis ; Nyarko-Danquah, Ivan ; Son, Deok-Soo ; Soliman, Karam F.A. ; Aschner, Michael ; Lee, Eunsook

The Journal of biological chemistry, 2021-12, Vol.297 (6), p.101372-101372, Article 101372 [Periódico revisado por pares]

United States: Elsevier Inc

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7
Manganese phosphorylates Yin Yang 1 at serine residues to repress EAAT2 in human H4 astrocytes
Manganese phosphorylates Yin Yang 1 at serine residues to repress EAAT2 in human H4 astrocytes
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Manganese phosphorylates Yin Yang 1 at serine residues to repress EAAT2 in human H4 astrocytes

Rizor, Asha ; Pajarillo, Edward ; Son, Deok-Soo ; Aschner, Michael ; Lee, Eunsook

Toxicology letters, 2022-02, Vol.355, p.41-46 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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8
Yin Yang 1 Is a Repressor of Glutamate Transporter EAAT2, and It Mediates Manganese-Induced Decrease of EAAT2 Expression in Astrocytes
Yin Yang 1 Is a Repressor of Glutamate Transporter EAAT2, and It Mediates Manganese-Induced Decrease of EAAT2 Expression in Astrocytes
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Yin Yang 1 Is a Repressor of Glutamate Transporter EAAT2, and It Mediates Manganese-Induced Decrease of EAAT2 Expression in Astrocytes

Karki, Pratap ; Webb, Anton ; Smith, Keisha ; Johnson, James ; Lee, Kyuwon ; Son, Deok-Soo ; Aschner, Michael ; Lee, Eunsook

Molecular and cellular biology, 2014-04, Vol.34 (7), p.1280-1289 [Periódico revisado por pares]

United States: Taylor & Francis

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9
cAMP Response Element-binding Protein (CREB) and Nuclear Factor κB Mediate the Tamoxifen-induced Up-regulation of Glutamate Transporter 1 (GLT-1) in Rat Astrocytes
cAMP Response Element-binding Protein (CREB) and Nuclear Factor κB Mediate the Tamoxifen-induced Up-regulation of Glutamate Transporter 1 (GLT-1) in Rat Astrocytes
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cAMP Response Element-binding Protein (CREB) and Nuclear Factor κB Mediate the Tamoxifen-induced Up-regulation of Glutamate Transporter 1 (GLT-1) in Rat Astrocytes

Karki, Pratap ; Webb, Anton ; Smith, Keisha ; Lee, Kyuwon ; Son, Deok-Soo ; Aschner, Michael ; Lee, Eunsook

The Journal of biological chemistry, 2013-10, Vol.288 (40), p.28975-28986 [Periódico revisado por pares]

United States: Elsevier Inc

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10
Transforming growth factor-α mediates estrogen-induced upregulation of glutamate transporter GLT-1 in rat primary astrocytes
Transforming growth factor-α mediates estrogen-induced upregulation of glutamate transporter GLT-1 in rat primary astrocytes
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Transforming growth factor-α mediates estrogen-induced upregulation of glutamate transporter GLT-1 in rat primary astrocytes

Lee, Eunsook ; Sidoryk-Wegrzynowicz, Marta ; Yin, Zhaobao ; Webb, Anton ; Son, Deok-Soo ; Aschner, Michael

Glia, 2012-07, Vol.60 (7), p.1024-1036 [Periódico revisado por pares]

Hoboken: Wiley Subscription Services, Inc., A Wiley Company

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